441 Results for "

Cell adhesion molecule

" in MedChemExpress (MCE) Product Catalog:
Products (441)

441 Results for "Cell adhesion molecule" in MCE Product Catalog:

Cat. No.: HY-P10580
CAS No.: 1359657-45-6
Vasculotide is a blood-brain barrier (BBB)-penetrant Tie2 agonist. Vasculotide binds to a unique domain of Tie2, induces receptor clustering to drive phosphorylation, activates downstream PI3K/Akt and eNOS pathways, enhances inter-endothelial cell junctions (such as VE-cadherin and claudin-5), and inhibits inflammatory adhesion molecules, ultimately stabilizing the vascular endothelial barrier and reducing its permeability . Vasculotide alleviates pulmonary microvascular leakage and microcirculatory dysfunction caused by cardiopulmonary bypass, acts as an adjuvant radioprotective agent to reduce acute radiation dermatitis, and promotes BBB recovery after focused ultrasound (FUS). Combination of Vasculotide with antibiotics reduces lung injury .
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Cat. No.: HY-P10580A
Vasculotide TFA is a blood-brain barrier (BBB)-penetrant Tie2 agonist. Vasculotide TFA binds to a unique domain of Tie2, induces receptor clustering to drive phosphorylation, activates downstream PI3K/Akt and eNOS pathways, enhances inter-endothelial cell junctions (such as VE-cadherin and claudin-5), and inhibits inflammatory adhesion molecules, ultimately stabilizing the vascular endothelial barrier and reducing its permeability . Vasculotide TFA alleviates pulmonary microvascular leakage and microcirculatory dysfunction caused by cardiopulmonary bypass, acts as an adjuvant radioprotective agent to reduce acute radiation dermatitis, and promotes BBB recovery after focused ultrasound (FUS). Combination of Vasculotide TFA with antibiotics reduces lung injury .
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Cat. No.: HY-P990275

Research Areas:  

Cancer

Anti-Mouse CD326/EpCAM Antibody (G8.8) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse CD326/EpCAM. Anti-Mouse CD326/EpCAM Antibody (G8.8) reacts with CD326 also known as EpCAM (Epithelial Cell Adhesion Molecule). Anti-Mouse CD326/EpCAM Antibody (G8.8) can be used for cancer research, such as lung carcinoma and colorectal carcinoma. Anti-Mouse CD326/EpCAM Antibody (G8.8) can be used for detections of western blot, immunohistochemistry, immunofluorescence and flow cytometry .
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Cat. No.: HY-W010697S
Cholesteryl linoleate-d11 is the d11-labeled Cholesteryl linoleate (HY-W010697). Cholesteryl linoleate is a cholesteryl ester with antibacterial activity that is present in low-density lipoprotein (LDL) particles, human nasal fluid, and respiratory epithelial secretions. Cholesteryl linoleate is oxidized by 12/15-lipoxygenase in macrophages and participates in selective uptake and efflux via LDL receptor-related protein. Cholesteryl linoleate does not induce endothelial adhesion molecule expression, nor does it induce monocyte binding to endothelial cells. Cholesteryl linoleate liposomal formulations inhibit the growth of multiple bacteria at physiological nasal fluid concentrations and act synergistically with antimicrobial peptides. Cholesteryl linoleate is useful for research related to atherosclerosis and bacterial infections .
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Cat. No.: HY-W509797
CAS No.: 21618-92-8
5-(3',4'-Dihydroxyphenyl)-γ-valerolactone is an intestinal microbiota metabolite of (-)-Epicatechin (HY-N0001). 5-(3',4'-Dihydroxyphenyl)-γ-valerolactone downregulates TNF-α-stimulated phosphorylation of IKK and IκBα, inhibits the transcriptional activation of NF-κB, and suppresses the expression of adhesion molecules and chemokines. 5-(3',4'-Dihydroxyphenyl)-γ-valerolactone promotes autophagy, alleviates oxidative stress, maintains osteoblast differentiation, induces G1 phase arrest, inhibits adipogenesis, and scavenges ABTS free radicals. 5-(3',4'-Dihydroxyphenyl)-γ-valerolactone inhibits the adhesion of uropathogenic Escherichia coli to bladder epithelial cells; when used in combination with Curcumin (HY-N0005), it downregulates the NLRP3 and NOX2/Nrf2 signaling pathways, thereby reducing microglial activation. 5-(3',4'-Dihydroxyphenyl)-γ-valerolactone can be used in research related to diabetes, atherosclerosis, osteoporosis, obesity, neurodegenerative diseases involving microglial activation, and urinary tract infections .
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Cat. No.: HY-P70083
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CADM3; FLJ10698; Prev. IGSF4B; Nectin-Like Protein 1; SynCAM3; TSLC1-Like Protein 1; TSLL1; Nectin-Like 1; NECL1; TSLC1-Like 1; Necl-1; SYNCAM3; BIgR; CMT2FF; Immunoglobulin Superfamily Member 4B; NECL-1; Synaptic Cell adhesion molecule 3; IgSF4B; Brain I
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P76187
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CADM4; TSLC1-Like Protein 2; Prev. IGSF4C; NECL4; TSLL2; Immunoglobulin Superfamily, Member 4C; SynCAM4; TSLC1-Like 2; Necl-4; NECL-4; Immunoglobulin Superfamily Member 4C; IgSF4C; Nectin-Like Protein 4; Cell adhesion molecule 4; Nectin-Like 4
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P76188
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CADM4; TSLC1-Like Protein 2; Prev. IGSF4C; NECL4; TSLL2; Immunoglobulin Superfamily, Member 4C; SynCAM4; TSLC1-Like 2; Necl-4; NECL-4; Immunoglobulin Superfamily Member 4C; IgSF4C; Nectin-Like Protein 4; Cell adhesion molecule 4; Nectin-Like 4
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P76189
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CADM4; TSLC1-Like Protein 2; Prev. IGSF4C; NECL4; TSLL2; Immunoglobulin Superfamily, Member 4C; SynCAM4; TSLC1-Like 2; Necl-4; NECL-4; Immunoglobulin Superfamily Member 4C; IgSF4C; Nectin-Like Protein 4; Cell adhesion molecule 4; Nectin-Like 4
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P76756
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CADM3; FLJ10698; Prev. IGSF4B; Nectin-Like Protein 1; SynCAM3; TSLC1-Like Protein 1; TSLL1; Nectin-Like 1; NECL1; TSLC1-Like 1; Necl-1; SYNCAM3; BIgR; CMT2FF; Immunoglobulin Superfamily Member 4B; NECL-1; Synaptic Cell adhesion molecule 3; IgSF4B; Brain I
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P76757
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: CADM3; FLJ10698; Prev. IGSF4B; Nectin-Like Protein 1; SynCAM3; TSLC1-Like Protein 1; TSLL1; Nectin-Like 1; NECL1; TSLC1-Like 1; Necl-1; SYNCAM3; BIgR; CMT2FF; Immunoglobulin Superfamily Member 4B; NECL-1; Synaptic Cell adhesion molecule 3; IgSF4B; Brain I
Species:  
Rat
Source:  
HEK293
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Cat. No.: HY-P76758
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CADM3; FLJ10698; Prev. IGSF4B; Nectin-Like Protein 1; SynCAM3; TSLC1-Like Protein 1; TSLL1; Nectin-Like 1; NECL1; TSLC1-Like 1; Necl-1; SYNCAM3; BIgR; CMT2FF; Immunoglobulin Superfamily Member 4B; NECL-1; Synaptic Cell adhesion molecule 3; IgSF4B; Brain I
Species:  
Rat
Source:  
HEK293
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Cat. No.: HY-P700962
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CADM3; FLJ10698; Prev. IGSF4B; Nectin-Like Protein 1; SynCAM3; TSLC1-Like Protein 1; TSLL1; Nectin-Like 1; NECL1; TSLC1-Like 1; Necl-1; SYNCAM3; BIgR; CMT2FF; Immunoglobulin Superfamily Member 4B; NECL-1; Synaptic Cell adhesion molecule 3; IgSF4B; Brain I
Species:  
Cynomolgus
Source:  
HEK293
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Cat. No.: HY-177434
CAS No.: 2873366-83-5
Synonyms: Precem-TcT; M 9140
Precemtabart tocentecan (Precem-TcT; M 9140) is an anti-CEACAM5 (carcinoembryonic antigen-related cell adhesion molecule 5) antibody-drug conjugate (ADC). Precemtabart tocentecan consists of a tumor-specific anti-CEACAM5 monoclonal antibody Precemtabart (HY-P990940), a highly hydrophilic and stable cleavable β-glucuronide linker, and a topoisomerase 1 inhibitor payload Exatecan (HY-13631), and the drug-linker conjugate for ADC is Mal-Gly-PAB-Exatecan-D-glucuronic acid (HY-153179). Precemtabart tocentecan inhibits the growth of CEACAM5-positive cancer cells. Precemtabart tocentecan exhibits significant antitumor activity in CEACAM5-expressing xenograft models. Precemtabart tocentecan can be used for the study of CEACAM5-expressing advanced solid tumors, especially mCRC .
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Cat. No.: HY-P70054
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CNTN2; Contactin 2 (Axonal); Prev. AXT; Contactin 2 (Transiently Expressed); Prev. TAX; Axonin-1 Cell adhesion molecule; TAX1; Alternative Protein CNTN2; Transient Axonal Glycoprotein 1; EPEO5; Axonal Glycoprotein TAG-1; FAME5; Contactin-2; TAX-1; TAG-1;
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P74223
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CNTN2; Contactin 2 (Axonal); Prev. AXT; Contactin 2 (Transiently Expressed); Prev. TAX; Axonin-1 Cell adhesion molecule; TAX1; Alternative Protein CNTN2; Transient Axonal Glycoprotein 1; EPEO5; Axonal Glycoprotein TAG-1; FAME5; Contactin-2; TAX-1; TAG-1;
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-79602S
CAS No.: 1219795-34-2
Synonyms: p-Tosylamide-d4
4-Tolyl-d4-sulfonamide (p-Tosylamide-d4) is the d4-labeled p-Toluenesulfonamide (HY-79602). p-Toluenesulfonamide is a small-molecule anticancer agent and plasticizer. p-Toluenesulfonamide exerts antitumor activity by inducing lysosomal membrane permeabilization, cathepsin B release and lysosome-mediated cell death. p-Toluenesulfonamide modulates cholesterol distribution in lipid rafts of tumor cell membranes and the Akt/mTOR/p70S6K pathway. p-Toluenesulfonamide shows activity against various cancers including hepatocellular carcinoma, non-small cell lung cancer and tongue squamous cell carcinoma; intrapleural injection effectively reduces malignant pleural effusion without causing pleural adhesion. p-Toluenesulfonamide is also the main degradation product of the disinfectant Chloramine-T (HY-B0959) in water. p-Toluenesulfonamide facilitates the localization of fluorescent probes to the endoplasmic reticulum. p-Toluenesulfonamide can be used in cancer-related research .
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Cat. No.: HY-N1353R
CAS No.: 569-92-6
Rhamnocitrin (Standard) is the analytical standard of Rhamnocitrin. This product is intended for research and analytical applications. Rhamnocitrin is an anti-inflammatory and antioxidant agent that targets STIM-1, NFATc3 and MAPK pathways and can scavenge DPPH (IC50=28.38 mM). Rhamnocitrin selectively inhibits oxidative stress and inflammatory responses in vascular endothelial cells and neurons. Rhamnocitrin up-regulates miR-185 to inhibit STIM-1-mediated store-operated calcium entry (SOCE), thereby blocking NFATc3 nuclear translocation and downstream inflammatory factor expression, while inducing heme oxygenase HO-1 expression and regulating the ERK/p38 MAPK pathway, inhibiting antioxidant and pro-inflammatory cytokines (such as IL-6, IL-8) and adhesion molecules (such as ICAM-1, VCAM-1). Rhamnocitrin can be used in the study of endothelial-related inflammatory diseases (such as sepsis, acute lung injury, atherosclerosis) and neuroprotection (such as oxidative damage of PC12 cells) .
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Cat. No.: HY-P78883
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: EPCAM; HEA125; Prev. TACSTD1; CO-17A; Prev. MIC18; EGP314; Prev. M4S1; EGP34; Tumor-Associated Calcium Signal Transducer 1; CD326; TROP1; MOC31; KSA; 17-1A; GA733-2; Ly74; Ber-Ep4; MH99; Ep-CAM; Membrane Component, Chromosome 4, Surface Marker (35kD Glycoprotein); MOC-31; Antigen Identified By Monoclonal Antibody AUA1; BerEp4; Human Epithelial Glycoprotein-2; EGP40; Epithelial Cell Surface Antigen; EGP-2; Epithelial Glycoprotein; KS1/4; KS 1/4 Antigen; MK-1; CD326 Antigen; ESA; HEGP314; Major Gastrointestinal Tumor-Associated Protein GA733-2; HNPCC8; Trophoblast Cell Surface Antigen 1; LYNCH8; Adenocarcinoma-Associated Antigen; DIAR5; Cell Surface Glycoprotein Trop-1; M1S2; Epithelial Glycoprotein 314; EGP; TACST-1; Epithelial Cell adhesion molecule; 323/A3
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P704581
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: EPCAM; HEA125; Prev. TACSTD1; CO-17A; Prev. MIC18; EGP314; Prev. M4S1; EGP34; Tumor-Associated Calcium Signal Transducer 1; CD326; TROP1; MOC31; KSA; 17-1A; GA733-2; Ly74; Ber-Ep4; MH99; Ep-CAM; Membrane Component, Chromosome 4, Surface Marker (35kD Glycoprotein); MOC-31; Antigen Identified By Monoclonal Antibody AUA1; BerEp4; Human Epithelial Glycoprotein-2; EGP40; Epithelial Cell Surface Antigen; EGP-2; Epithelial Glycoprotein; KS1/4; KS 1/4 Antigen; MK-1; CD326 Antigen; ESA; HEGP314; Major Gastrointestinal Tumor-Associated Protein GA733-2; HNPCC8; Trophoblast Cell Surface Antigen 1; LYNCH8; Adenocarcinoma-Associated Antigen; DIAR5; Cell Surface Glycoprotein Trop-1; M1S2; Epithelial Glycoprotein 314; EGP; TACST-1; Epithelial Cell adhesion molecule; 323/A3
Species:  
Human
Source:  
HEK293
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