2419 Results for "

decrease

" in MedChemExpress (MCE) Product Catalog:
Products (2419)

2419 Results for "decrease" in MCE Product Catalog:

Cat. No.: HY-101606
CAS No.: 62992-61-4
Synonyms: Eterylate; Etherylate
Etersalate inhibits platelet function and decreases thromboxane A2 (TXA2) levels.
loading...
    loading...
Cat. No.: HY-104037A
CAS No.: 2055538-47-9
Synonyms: LYC-55716 sodium
Target:  

ROR

Research Areas:  

Cancer

Cintirorgon sodium is a first-in-class, selective and orally bioavailable RORγ agonist. Cintirorgon sodium (LYC-55716) modulates gene expression of RORγ expressing T lymphocyte immune cells, resulting in enhanced effector function, as well as decreased immunosuppression, resulting in decreased tumor growth, and improved survival .
loading...
    loading...
Cat. No.: HY-159518
CAS No.: 2959444-40-5
ROS inducer 4 (compound TE3) is a mitochondrial inhibitor. ROS inducer 4 causes a series of mitochondria-related physiological changes in tumors, such as mitochondrial fragmentation, explosive generation and accumulation of ROS, decreased mitochondrial membrane potential, decreased ATP content, and activation of ROS-mediated apoptotic signaling in mitochondria .
loading...
    loading...
Cat. No.: HY-107992
CAS No.: 79770-24-4
Iotrolan is a non-ionic contrast agent. Iotrolan induces Apoptosis. Iotrolan decreases glomerular filtration rate and renal perfusate flow, increases urine flow, and does not significantly decrease fractional sodium reabsorption. Iotrolan can be used in studies of COVID-19 and contrast-induced nephrotoxicity .
loading...
    loading...
Cat. No.: HY-158333
CAS No.: 88579-39-9
Target:  

Mucin

Research Areas:  

Others

Tasuldine is a mucolytic agent, which decreases the sialomucin content of mucus, improves mucociliary and cough clearance .
loading...
    loading...
Cat. No.: HY-110216
CAS No.: 827001-82-1
Purity:  95%
Target:  

CRAC Channel

Research Areas:  

Inflammation/Immunology

5J-4 is a potent CRAC inhibitor. 5J-4 decreases the numbers of infiltrated mononuclear cell into the CNS, and significantly decreases the population of infiltrated CD4+ population. 5J-4 reduces the symptoms and delayed the onset of EAE (experimental autoimmune encephalomyelitis) in mouse model of inflammation .
loading...
    loading...
Cat. No.: HY-120067
CAS No.: 183012-13-7
Target:  

Cytochrome P450

Research Areas:  

Endocrinology

YM116 is an orally active and competitive CYP17A1 (17,20-lyase) inhibitor (Ki: 0.38 nM). YM116 reduces the synthesis of adrenal androgens by preferentially inhibiting C17-20 lyase activity. YM116 decreases the serum testosterone concentration, reduces dehydroepiandrosterone sulfate levels and decreases prostatic weights .
loading...
    loading...
Cat. No.: HY-122007
CAS No.: 1202764-63-3
Target:  

NF-κB

Research Areas:  

Cancer

AM-0561 is a NIK inhibitor (Ki: 0.3 nM). AM-0561 decreases p52 levels .
loading...
    loading...
Cat. No.: HY-114929
CAS No.: 104741-27-7
Target:  

Glutaminase

Research Areas:  

Neurological Disease

THDP17 is an orally active glutaminase inhibitor. THDP17 decreases ammonia production through glutaminase inhibition .
loading...
    loading...
Cat. No.: HY-168884
CAS No.: 2713387-11-0
Target:  

mTOR

Research Areas:  

Metabolic Disease

AV457 is a potent and selective mTOR inhibitor with an IC50 value of 0.54 µM. AV457 inhibits cyst growth in polycystic kidney disease (PKD) organoids. AV457 decreases the protein expression of P-s6, P-p70s6 and don’t decreases the protein expression of P-AKT .
loading...
    loading...
Cat. No.: HY-130434
CAS No.: 51350-61-9
Target:  

Endogenous Metabolite

Research Areas:  

Cancer

12-SAHSA is a fatty acid ester of hydroxy fatty acids (FAHFAs). 12-SAHSA decreases in the human serum of breast cancer .
loading...
    loading...
Cat. No.: HY-124560
CAS No.: 96609-16-4
Target:  

LDLR

Research Areas:  

Metabolic Disease

Lifibrol is a potent and oral activity hypolipidemic agent. Lifibrol decreases the plasma total cholesterol. Lifibrol has the potential for the research of hypercholesterolemia .
loading...
    loading...
Cat. No.: HY-114189A
CAS No.: 179246-08-3
Synonyms: UNC10225170 hydrochloride
Target:  

MEK

Research Areas:  

Cancer

GW284543 (UNC10225170) hydrochloride is a selective MEK5 inhibitor. GW284543 reduces pERK5, and decreases endogenous MYC protein .
loading...
    loading...
Cat. No.: HY-160436
CAS No.: 364039-58-7
Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

TNF-α-IN-15 is a TNF-α inhibitor. TNF-α-IN-15 can decrease the TNF-α blood levels .
loading...
    loading...
Cat. No.: HY-P5069
CAS No.: 97451-40-6
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Glutathione diethyl ester is a delivery agent for glutathione monoester, and thus for glutathione, in human cells and therefore could serve to decrease oxidative stress and toxicity .
loading...
    loading...
Cat. No.: HY-126482
CAS No.: 1610878-54-0
Purity:  99.79%
Target:  

Telomerase

Research Areas:  

Cancer

Telomerase-IN-2 is a telomerase inhibitor, and inhibits telomerase activity by decreasing expression of dyskerin, with an IC50 of 0.89 µM. Anti-cancer activity .
loading...
    loading...
Cat. No.: HY-17556B
CAS No.: 1097832-14-8
Synonyms: Leucovorin calcium hydrate
Folinic acid (Leucovorin) calcium hydrate is a biological folic acid and is generally administered along with Methotrexate (HY-14519) as a rescue agent to decrease Methotrexate-induced toxicity .
loading...
    loading...
Cat. No.: HY-N1616
CAS No.: 120211-98-5
1β-Hydroxyeuscaphic acid has significant hepatoprotective activity by lowering the leakage of intracellular enzymes, reducing the oxidation of proteins and decreasing the incidence of apoptosis .
loading...
    loading...
Cat. No.: HY-105259
CAS No.: 114037-60-4
Target:  

Renin

Research Areas:  

Cardiovascular Disease

SR 43845 is a renin inhibitor. SR 43845 decreases blood pressure and inhibits plasma renin activity. SR 43845 can be used for hypertension research .
loading...
    loading...
Cat. No.: HY-113797
CAS No.: 62435-92-1
Target:  

Adrenergic Receptor

Research Areas:  

Others

RS-52367 is a potent syntex β-adrenergic antagonist. RS-52367 decreases intraocular pressure with a mild systemic effect in dogs .
loading...
    loading...