2419 Results for "

decrease

" in MedChemExpress (MCE) Product Catalog:
Products (2419)

2419 Results for "decrease" in MCE Product Catalog:

Cat. No.: HY-P4786
CAS No.: 1815618-01-9
Target:  

Androgen Receptor

Acetyl-ACTH (7-24) (human, bovine, rat) causes a marked decrease of ACTH-evoked corticosterone and aldosterone release .
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Cat. No.: HY-P4253A
Synonyms: H-Arg-Gln-OH TFA
Target:  

VEGFR

Research Areas:  

Cardiovascular Disease

Arginyl-Glutamine TFA is a dipeptide that can decrease VEGF levels and inhibit retinal neovascularization in a mouse model of oxygen-induced retinopathy .
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Cat. No.: HY-B1348
CAS No.: 695-53-4
Target:  

Drug Metabolite

Research Areas:  

Neurological Disease

Dimethadione is the primary metabolite of trimethadione. Dimethadione causes depression of neuromuscular transmission. Dimethadione primarily decreases transmitter release from the nerve terminal .
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Cat. No.: HY-148158
CAS No.: 306-19-4
Synonyms: Pivhydrazine
Pivalylbenzhydrazine (Pivhydrazine) is a potent monoamine oxidase (MAO) inhibitor. Pivalylbenzhydrazine decreases cartilage growth in normal rats. Pivalylbenzhydrazine can be used in research of depression .
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Cat. No.: HY-143401
CAS No.: 2785377-42-4
Target:  

IDE

Research Areas:  

Metabolic Disease

Hit 1 is an activator of ansulin degrading enzyme (IDE), with an EC50 of 5.5 μM. Hit 1 can decrease glucose-stimulating insulin secretion .
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Cat. No.: HY-112070
CAS No.: 15687-41-9
Target:  

Adrenergic Receptor

Research Areas:  

Cardiovascular Disease

Oxyfedrine, a vasodilator, is an orally active β-adrenoreceptor agonist. Oxyfedrine decreases the tonicity of coronary vessels. Oxyfedrine can be used in the research of cardiovascular disease .
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Cat. No.: HY-N3486
CAS No.: 139726-30-0
Isodunnianol is a autophagy inducer. Isodunnianol induces autophagy and increases he expression of pAMPK172, pULK1555,decreases teh expression of pULK1757, SQSTM2. Isodunnianol decreases Doxorubicin (HY-15142A)-induced cardiotoxicity .
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Cat. No.: HY-N0582
CAS No.: 106758-54-7
Otophylloside B, a C-21 steroidal glycoside isolated from Qingyangshen. Otophylloside B protects against Aβ toxicity, which decreases Aβ deposition by decreasing the expression of Aβ at the mRNA level. Otophylloside B has antiepileptic activity .
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Cat. No.: HY-139576C
CAS No.: 2655654-16-1
Synonyms: DUR-928 ammonium
Research Areas:  

Metabolic Disease

Larsucosterol (DUR-928) ammonium, a cholesterol metabolite, is a potent liver X receptor (LXR) antagonist. Larsucosterol ammonium as a potent endogenous regulator decreases lipogenesis. Larsucosterol ammonium inhibits the cholesterol biosynthesis via decreasing mRNA levels and inhibiting the activation of SREBP-1 .
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Cat. No.: HY-113821
CAS No.: 100929-85-9
Target:  

Phosphatase

Research Areas:  

Others

1-Naphthyl phosphate potassium salt is a non-specific phosphatase inhibitor. 1-Naphthyl phosphate potassium salt decreases the splice-correcting effect .
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Cat. No.: HY-125088
CAS No.: 180003-17-2
Target:  

Apoptosis

Research Areas:  

Metabolic Disease

Oleoylestrone, an adipose tissue-derived hormonal signal, is a slimming agent that decreases food intake and maintains energy expenditure .
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Cat. No.: HY-168483
CAS No.: 687600-25-5
FTO-IN-13 (compound 8t) is a potent FTO inhibitor. FTO-IN-13 shows antiproliferative activity. FTO-IN-13 induces apoptosis. FTO-IN-13 decreases the protein expression of Bcl-2 and Caspase 3 active. FTO-IN-13 decreases MYC and CEBPA gene expression. FTO-IN-13 shows anticancer activity .
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Cat. No.: HY-106767
CAS No.: 61887-16-9
Research Areas:  

Metabolic Disease

Dulofibrate is a hypolipidaemic agent that induces microsomal drug-metabolizing enzymes. Dulofibrate is selective for a reduction in triglycerides. Dulofibrate decreases nopol conjugation .
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Cat. No.: HY-101595
CAS No.: 96558-24-6
Target:  

Drug Derivative

Research Areas:  

Others

RPH-2823, a basic triamterene derivative, induces a dose-dependent decrease in short-circuit current (SCC) and increase in transepithelial electrical resistance .
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Cat. No.: HY-105795
CAS No.: 5800-19-1
Target:  

Drug Derivative

Research Areas:  

Neurological Disease

Metiapine is a new antipsychotic agent and Dibenzothiazepine derivative. Metiapine produces a decrease in food consumption. Metiapine can be used in the research of schizophrenia .
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Cat. No.: HY-N0261R
CAS No.: 67979-25-3
Aurantio-obtusin (Standard) is the analytical standard of Aurantio-obtusin. This product is intended for research and analytical applications. Aurantio-obtusin is a anthraquinone compound that can be extracted from cassia seed. Aurantio-obtusin has the effects of decreasing blood pressure, decreasing blood lipids and anti-inflammatory.Aurantio-obtusin is an orally active vasodilator. Aurantio-obtusin ameliorates hepatic steatosis through AMPK/ autophagy-and AMPK/TFEB mediated inhibition of lipid accumulation .
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Cat. No.: HY-16403
CAS No.: 346-18-9
Target:  

Sodium Channel

Research Areas:  

Cardiovascular Disease

Polythiazide is a potent and orally active thiazide diuretic agent that has antihypertensive effect. Polythiazide can decrease edema and decrease blood pressure. Polythiazide also has phototoxicity .
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Cat. No.: HY-129694
CAS No.: 51257-84-2
Synonyms: Ro 21-6150; Antibiotic A-130-A
Lenoremycin (Ro 21-6150) is a microbial metabolite. Lenoremycin decreases β-catenin and cyclin D1 proteins levels. Lenoremycin decreases cancer stem cells (CSCs) populations via inducing reactive oxygen species production .
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Cat. No.: HY-139576A
CAS No.: 1174047-40-5
Synonyms: DUR-928 sodium
Larsucosterol (DUR-928) sodium, a cholesterol metabolite, is a potent liver X receptor (LXR) antagonist. Larsucosterol sodium as a potent endogenous regulator decreases lipogenesis. Larsucosterol sodium inhibits the cholesterol biosynthesis via decreasing mRNA levels and inhibiting the activation of SREBP-1 .
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Cat. No.: HY-118656
CAS No.: 31508-71-1
Target:  

Cannabinoid Receptor

Research Areas:  

Neurological Disease

Cannabicitran is a cannabinoid. Cannabicitran can decrease intraocular pressure in rabbits .
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