2419 Results for "

decrease

" in MedChemExpress (MCE) Product Catalog:
Products (2419)

2419 Results for "decrease" in MCE Product Catalog:

Cat. No.: HY-104056
CAS No.: 149732-62-7
Fura Red is a Ca 2+-sensitive fluorescent dye, which decreases in fluorescence with rising [Ca 2+] .
loading...
    loading...
Cat. No.: HY-N0229R
CAS No.: 56-41-7
Synonyms: L-2-Aminopropionic acid (Standard)
L-Alanine (Standard) is the analytical standard of L-Alanine. This product is intended for research and analytical applications. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system. In Vitro: The viability of both hiPSCs, 201B7 cells and ehiPSCs decrease with an increase in L-Alanine concentration, and reach 7.5±1.3% and 3.7±0.7% respectively at 1.2 M of L-Alanine. On the other hand, no decrease in the viability of hFBs and hSkMCs are observed. Although the viability of iCMs slightly decreases along with the increase of the L-Alanine concentration, viability of iCMs at 1.2 M concentration of L-Alanine, 49.4±6.9%, is significantly higher than that of undifferentiated iPSCs, 201B7 cells and ehiPSCs (p< 0.01). The viability of hiPSCs, 201B7 cells and ehiPSCs, drastically decrease even after 2 or 4 h treatment. In contrast, the viability of hFBs fails to decrease at 1, 2, and 4 h and shows a small decrease at 24 h treatment. The viability of 201B7 cells in suspension culture decreases to 11.8±6.0% following treatment with 1.2 M L-Alanine for 2 h, whereas that of hFBs is 72.9±14.2% .
loading...
    loading...
Cat. No.: HY-P4253
CAS No.: 2483-17-2
Synonyms: H-Arg-Gln-OH
Target:  

VEGFR

Research Areas:  

Cardiovascular Disease

Arginyl-Glutamine is a dipeptide that can decrease VEGF levels and inhibit retinal neovascularization in a mouse model of oxygen-induced retinopathy .
loading...
    loading...
Cat. No.: HY-125062
CAS No.: 60129-60-4
Purity:  99.87%
Synonyms: Glucosilsteviol
Target:  

GLUT

Research Areas:  

Metabolic Disease

Steviolmonoside (Glucosilsteviol) is a structural analogue of steviol. Steviolmonoside decreases glucose production and inhibits oxygen uptake in rat renal cortical tubules .
loading...
    loading...
Cat. No.: HY-121650A
CAS No.: 13575-86-5
Purity:  98.0%
ADTN hydrobromide is a long-acting dopamine agonist. ADTN hydrobromide significantly decreases the behavioral visual threshold of DA-IPC-depleted zebrafish .
loading...
    loading...
Cat. No.: HY-W023493
CAS No.: 7685-44-1
Synonyms: 2-Aminopent-4-enoic acid
Research Areas:  

Neurological Disease

DL-Allylglycine (2-Aminopent-4-enoic acid) is a glutamate decarboxylase (GAD) inhibitor. DL-Allylglycine significantly increases mouse brain ornithine decarboxylase (ODC) activity and decreases S-adenosyl-L-methionine decarboxylase (SAM-DC) activity. DL-Allylglycine causes a marked decrease in brain GABA concentration. DL-Allylglycine has convulsant activity that can be used in studies to induce epileptic seizures .
loading...
    loading...
Cat. No.: HY-P5069A
Research Areas:  

Inflammation/Immunology

Glutathione diethyl ester (TFA) is a delivery agent for glutathione monoester, and thus for glutathione, in human cells and therefore could serve to decrease oxidative stress and toxicity .
loading...
    loading...
Cat. No.: HY-168608
CAS No.: 1909225-07-5
Research Areas:  

Cancer

TRPM7-IN-1 (compound SUD), a benzoylurea derivative, is an effective TRPM7 inhibitor. TRPM7-IN-1 induces cell cycle arrest and apoptosis, decreases the migration of MCF-7 and BGC-823 cells. TRPM7-IN-1 decreases vimentin expression and increases E-cadherin expression. TRPM7-IN-1 potentially reduces the TRPM7-like current and decreases TRPM7 expression through the PI3K/Akt signaling pathway. TRPM7-IN-1 is a potential agent to suppress the metastasis of breast and gastric cancer by inhibiting TRPM7 expression and function .
loading...
    loading...
Cat. No.: HY-108300
CAS No.: 16777-42-7
Purity:  99.92%
Target:  

Adrenergic Receptor

Research Areas:  

Cardiovascular Disease

Oxyfedrine hydrochloride, a vasodilator, is an orally active β-adrenoreceptor agonist. Oxyfedrine decreases the tonicity of coronary vessels. Oxyfedrine hydrochloride can be used in the research of cardiovascular disease .
loading...
    loading...
Cat. No.: HY-112649
CAS No.: 2332841-83-3
Purity:  99.37%
Target:  

STAT Apoptosis

Research Areas:  

Cancer

Pomstafib-2 is a potent and selective STAT5b inhibitor. Pomstafib-2 decreases the expression of pSTAT5b and induces Apoptosis .
loading...
    loading...
Cat. No.: HY-139576
CAS No.: 884905-07-1
Synonyms: DUR-928
Larsucosterol (DUR-928), a cholesterol metabolite, is a potent liver X receptor (LXR) antagonist. Larsucosterol as a potent endogenous regulator decreases lipogenesis. Larsucosterol inhibits the cholesterol biosynthesis via decreasing mRNA levels and inhibiting the activation of SREBP-1 .
loading...
    loading...
Cat. No.: HY-N16535
CAS No.: 289499-72-5
Stigmalactam is an aristolactam-type alkaloid extracted from Orophea enterocarpa with anticancer effects. Stigmalactam induces apoptosis via the mitochondrial pathway, with the activation of caspase-3/9, and a decrease in mitochondrial membrane potential (MTP). Stigmalactam exhibits antioxidant activity by decreasing ROS production. Stigmalactam can be used for liver and breast cancer research .
loading...
    loading...
Cat. No.: HY-W105699
CAS No.: 13235-36-4
Synonyms: Ethylenediaminetetraacetic acid tetrasodium tetrahydrate
EDTA tetrasodium tetrahydrate is a metal chelator (binds to metal divalent and trivalent cations including calcium), which shows activities of anticoagulant and anti-hypercalcemic. EDTA tetrasodium tetrahydrate decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. EDTA tetrasodium tetrahydrate can also decrease the formation of disulfide bonds .
loading...
    loading...
Cat. No.: HY-135066
CAS No.: 1471-17-6
Synonyms: Pentaerythritol triallyl ether
Research Areas:  

Others

Triallyl pentaerythritol (PEATA), a crosslinker, decreases the protein rejection compared to membranes functionalized with MBAA or without any crosslinker .
loading...
    loading...
Cat. No.: HY-Y0682S1
CAS No.: 203805-96-3
Synonyms: EDTA-d16
Ethylenediaminetetraacetic acid-d16 is the deuterium labeled Ethylenediaminetetraacetic acid . Ethylenediaminetetraacetic acid (EDTA) is a metal chelators (binds to metal divalent and trivalent cations including calcium), which shows activities of anticoagulant and anti-hypercalcemic. Ethylenediaminetetraacetic acid decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid can also decrease the formation of disulfide bonds .
loading...
    loading...
Cat. No.: HY-155335
CAS No.: 2829263-19-4
Purity:  99.39%
Research Areas:  

Inflammation/Immunology

FPR2 agonist 3 (compound CMC23) can limit the lactate dehydrogenase release in LPS (HY-D1056) -stimulated cultures and decrease the levels of pro-inflammatory IL-1β and IL-6. FPR2 agonist 3 decrease the level of phosphor-STAT3 via the STAT3/SOCS3 signaling pathway .
loading...
    loading...
Cat. No.: HY-118961
CAS No.: 311814-78-5
Target:  

Kinesin

Research Areas:  

Cancer

SR31527 chloride is a potent KIFC1 inhibitor with an IC50 value of 6.6 µM. SR31527 chloride decreases cell viability and colony formation .
loading...
    loading...
Cat. No.: HY-100485
CAS No.: 149556-49-0
Target:  

Drug Derivative

Research Areas:  

Inflammation/Immunology

Susalimod is an immunomodulating agent and Sulfasalazine (HY-14655) analogue. Susalimod decreases LPS-induced TNF-alpha mouse serum levels .
loading...
    loading...
Cat. No.: HY-N3480
CAS No.: 53319-52-1
Synonyms: (+)-Isogospherol; Isogospherol
Isogosferol ((+)-Isogospherol; Isogospherol) is a potent anti-inflammatory agent. Isogosferol decreases LPS (HY-D1056)-stimulated NO and IL-1β expression. Isogosferol decreases the LPS (HY-D1056)-stimulated expression of iNOS, COX-2, NF-κB, and pERK1/2 .
loading...
    loading...
Cat. No.: HY-N7800
CAS No.: 6879-74-9
Synonyms: (+)-Himbacine
Himbacine ((+)-Himbacine) is a potent antihypertensive agent. Himbacine decreases in both mean blood pressure and heart rate .
loading...
    loading...