637 Results for "

interferon-

" in MedChemExpress (MCE) Product Catalog:
Products (637)

637 Results for "interferon-" in MCE Product Catalog:

Cat. No.: HY-P82797
Synonyms: CXCL10; INP10; SCYB10; C-X-C motif chemokine 10; 10 kDa interferon gamma-induced protein; Gamma-IP10; IP-10; Small-inducible cytokine B10

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human

loading...
    loading...
Cat. No.: HY-P86956
Synonyms: CARD adapter inducing interferon beta antibody; CARD adaptor inducing IFN beta antibody; Cardif antibody; DKFZp666M015 antibody; FLJ27482 antibody; FLJ41962 antibody; IFN B promoter stimulator 1 antibody; interferon beta promoter stimulator protein 1 antibody; Ips 1 antibody; IPS-1 antibody; CARD adapter inducing interferon beta antibody; CARD adaptor inducing IFN beta antibody; Cardif antibody; DKFZp666M015 antibody; FLJ27482 antibody; FLJ41962 antibody; IFN B promoter stimulator 1 antibody; interferon beta promoter stimulator protein 1 antibody; Ips 1 antibody; IPS-1 antibody; Ips1 antibody; KIAA1271 antibody; MAVS antibody; MAVS_HUMAN antibody; Mitochondrial anti viral signaling protein antibody; Mitochondrial Antiviral Signaling antibody; Mitochondrial antiviral signaling protein antibody; Mitochondrial antiviral-signaling protein antibody; Putative NF kappa B activating protein 031N antibody; Putative NF-kappa-B-activating protein 031N antibody; Virus induced signaling adapter antibody; virus induced signaling adaptor antibody; Virus-induced-signaling adapter antibody; VISA antibody;

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IF-Tissue

Reactivity:  

Human

loading...
    loading...
Cat. No.: HY-P703082
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: MAVS; Mitochondrial Antiviral-Signaling Protein; Mitochondrial Antiviral Signaling Protein; CARD Adapter Inducing interferon Beta; Cardif; Virus-Induced Signaling Adaptor; IPS-1; Virus-Induced-Signaling Adapter; VISA; CARD Adaptor Inducing IFN-Beta; KIAA1
Species:  
Human
Source:  
E. coli
loading...
    loading...
Cat. No.: HY-P85459
Synonyms: PRMT1; HMT2; HRMT1L2; IR1B4; Protein arginine N-methyltransferase 1; Histone-arginine N-methyltransferase PRMT1; interferon receptor 1-bound protein 4

Host:  

Mouse

Application:  

WB

Reactivity:  

Human, Mouse, Rat, Dog, Rabbit

loading...
    loading...
Cat. No.: HY-P990233

Target:  

IFNAR

Anti-Mouse IFNγR/CD119 Antibody (GR-20) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse IFNγR/CD119.Anti-Mouse IFNγR/CD119 Antibody (GR-20) reacts with the mouse IFNγR (interferon gamma receptor) α chain also known as CD119 and IFNγ receptor 1. Anti-Mouse IFNγR/CD119 Antibody (GR-20) blocks the binding of IFNγ to CD119 therefore inhibiting IFNγ signaling. Anti-Mouse IFNγR/CD119 Antibody (GR-20) can be used for the researches of cancer, infection, inflammation and immunology, such as melanoma and C. trachomatis infected genital tract inflammation .
loading...
    loading...
Cat. No.: HY-P701994
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PYHIN1; interferon-Inducible Protein X; Pyrin And HIN Domain Family Member 1; MGC23885; IFIX; Pyrin And HIN Domain Family, Member 1; Pyrin And HIN Domain-Containing Protein 1
Species:  
Human
Source:  
E. coli
loading...
    loading...
Cat. No.: HY-P7488
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: AIF1; interferon Gamma Responsive Transcript; Allograft Inflammatory Factor 1; Em:AF129756.17; AIF-1; Protein G1; IBA1; IRT1; Ionized Calcium-Binding Adapter Molecule 1; G1; IRT-1
Species:  
Human
Source:  
E. coli
loading...
    loading...
Cat. No.: HY-P71134
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: WARS1; Tryptophanyl-TRNA Synthetase 1; IFI53; WARS; IFP53; Tryptophan--TRNA Ligase, Cytoplasmic; Tryptophanyl-TRNA Synthetase; Tryptophan TRNA Ligase 1, Cytoplasmic; interferon-Induced Protein 53; TrpRS; HWRS; Epididymis Secretory Sperm Binding Protein; T
Species:  
Human
Source:  
E. coli
loading...
    loading...
Cat. No.: HY-P72075
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: AIF1; interferon Gamma Responsive Transcript; Allograft Inflammatory Factor 1; Em:AF129756.17; AIF-1; Protein G1; IBA1; IRT1; Ionized Calcium-Binding Adapter Molecule 1; G1; IRT-1
Species:  
Mouse
Source:  
E. coli
loading...
    loading...
Cat. No.: HY-P7488A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: AIF1; interferon Gamma Responsive Transcript; Allograft Inflammatory Factor 1; Em:AF129756.17; AIF-1; Protein G1; IBA1; IRT1; Ionized Calcium-Binding Adapter Molecule 1; G1; IRT-1
Species:  
Human
Source:  
E. coli
loading...
    loading...
Cat. No.: HY-105067A
CAS No.: 922174-60-5
Synonyms: GV-1001 hydrochloride
Tertomotide hydrochloride (GV-1001 hydrochloride) is a 16-amino acid peptide derived from hTERT, with both cell-penetrating and immunostimulatory activities, and it can cross the blood-brain barrier. Tertomotide hydrochloride binds to STING, HO-1, eHSP70, eHSP90, bradykinin receptor 1, VEGFR-2, NF-κB, p38 MAPK and Smad2. Tertomotide hydrochloride induces type I interferon production, mitochondrial DNA stress and T-cell responses; inhibits HBV replication, angiogenesis, TGF-β signaling pathway, NF-κB activation, endothelial-mesenchymal transition (EndMT) and fibrosis; regulates microglia; and exerts neuroprotective, anti-inflammatory, antioxidant, anti-apoptotic and anti-tumor effects. Tertomotide hydrochloride can be used in research related to hepatitis B virus infection, Alzheimer's disease, non-small cell lung cancer, atherosclerosis and depression .
loading...
    loading...
Cat. No.: HY-113308AS1
CAS No.: 1265476-97-8
Taurolithocholic Acid-d5 (sodium) is the deuterium labeled Taurolithocholic acid sodium salt. Taurolithocholic Acid sodium salt is an orally active bile acid and antiviral agent. Taurolithocholic Acid sodium salt upregulates FADS2 by activating the TGR5-PI3K/AKT-SREBP2 signaling axis, inhibits SFTSV-induced ferroptosis, viral replication and viral entry of HBV/HDV, while reducing the release of IL-1β, lipid ROS and LDH. While exerting antiviral protective effects, Taurolithocholic Acid sodium salt also stimulates the recycling of hepatocellular membrane transporters, impairs canalicular bile acid secretion function, and induces hepatocyte cholestasis, apoptosis and acute hepatocellular injury. Taurolithocholic Acid sodium salt serves as an experimental model compound for hepatocellular cholestasis. At concentrations ≤200 μM, Taurolithocholic Acid sodium salt shows no cytotoxicity and does not activate the interferon pathway. Taurolithocholic Acid sodium salt not only protects mice from lethal SFTSV infection but also is suitable for studies related to severe fever with thrombocytopenia syndrome and cholestasis .
loading...
    loading...
Cat. No.: HY-113308AS2
Taurolithocholic acid-d4-1 (sodium) is the deuterium labeled Taurolithocholic acid. Taurolithocholic acid sodium is an orally active bile acid and antiviral agent. Taurolithocholic acid sodium upregulates FADS2 by activating the TGR5-PI3K/AKT-SREBP2 signaling axis, inhibits SFTSV-induced ferroptosis, viral replication and viral entry of HBV/HDV, while reducing the release of IL-1β, lipid ROS and LDH. While exerting antiviral protective effects, Taurolithocholic acid sodium also stimulates the recycling of hepatocellular membrane transporters, impairs canalicular bile acid secretion function, and induces hepatocyte cholestasis, apoptosis and acute hepatocellular injury. Taurolithocholic acid sodium serves as an experimental model compound for hepatocellular cholestasis. At concentrations ≤200 μM, Taurolithocholic acid sodium shows no cytotoxicity and does not activate the interferon pathway. Taurolithocholic acid sodium not only protects mice from lethal SFTSV infection but also is suitable for studies related to severe fever with thrombocytopenia syndrome and cholestasis .
loading...
    loading...
Cat. No.: HY-113308S
CAS No.: 1265681-64-8
Taurolithocholic acid-d5 is deuterium labeled Taurolithocholic acid. Taurolithocholic acid is an orally active bile acid and antiviral agent. Taurolithocholic acid upregulates FADS2 by activating the TGR5-PI3K/AKT-SREBP2 signaling axis, inhibits SFTSV-induced ferroptosis, viral replication and viral entry of HBV/HDV, while reducing the release of IL-1β, lipid ROS and LDH. While exerting antiviral protective effects, Taurolithocholic acid also stimulates the recycling of hepatocellular membrane transporters, impairs canalicular bile acid secretion function, and induces hepatocyte cholestasis, apoptosis and acute hepatocellular injury. Taurolithocholic acid serves as an experimental model compound for hepatocellular cholestasis. At concentrations ≤200 μM, Taurolithocholic acid shows no cytotoxicity and does not activate the interferon pathway. Taurolithocholic acid not only protects mice from lethal SFTSV infection but also is suitable for studies related to severe fever with thrombocytopenia syndrome and cholestasis .
loading...
    loading...
Cat. No.: HY-P2114
CAS No.: 173959-12-1
Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

IT9302 is a synthetic IL-10 agonist with the activity of inducing tolerogenic dendritic cells. IT9302 is able to mimic multiple effects of IL-10, including downregulating the antigen presentation machinery and increasing the sensitivity of tumor cells to natural killer cell-mediated lysis. IT9302 can also hinder the response of human monocytes to differentiation factors and reduce the antigen presentation and co-stimulatory capacity of dendritic cells. Dendritic cells treated with IT9302 showed a weakened ability to stimulate T cell proliferation and interferon-γ production. IT9302 exerts its effects through mechanisms that are partially different from IL-10, involving STAT3 inactivation and regulation of the NF-κB intracellular pathway. IT9302-treated dendritic cells showed enhanced expression of membrane-bound TGF-β, associated with the effective induction of foxp3+ regulatory T cells .
loading...
    loading...
Cat. No.: HY-L088
3,660 compounds

Angiogenesis is the physiological process through which new blood vessels are formed from pre-existing vessels. It occurs in various physiological processes e.g. embryonic development, menstrual cycle, exercise and wound healing etc. Angiogenesis is regulated by both endogenous activators and inhibitors. Some key activators of angiogenesis include vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), angiogenin, TGF-β, etc. whereas angiogenesis inhibitors are angiostatin, endostatin, interferon, platelet factor 4, etc. The loss of balance between these opposing signals leads to life threatening diseases like cancer, cardiovascular and ischemic diseases etc. which are thus controlled by exogenous angiogenesis activators (for cardiovascular/ischemic disorders) and inhibitors (for cancer).

MCE offers a unique collection of 3,660 compounds with validated angiogenesis targets modulating properties. MCE angiogenesis-related compound library is an effective tool for angiogenesis research and discovery of angiogenesis-related drugs.

Cat. No.: HY-P73540
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: WARS1; Tryptophanyl-TRNA Synthetase 1; IFI53; WARS; IFP53; Tryptophan--TRNA Ligase, Cytoplasmic; Tryptophanyl-TRNA Synthetase; Tryptophan TRNA Ligase 1, Cytoplasmic; interferon-Induced Protein 53; TrpRS; HWRS; Epididymis Secretory Sperm Binding Protein; T
Species:  
Human
Source:  
Sf9 insect cells
loading...
    loading...
Cat. No.: HY-P700529
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: AIF1; interferon Gamma Responsive Transcript; Allograft Inflammatory Factor 1; Em:AF129756.17; AIF-1; Protein G1; IBA1; IRT1; Ionized Calcium-Binding Adapter Molecule 1; G1; IRT-1
Species:  
Bovine
Source:  
E. coli
loading...
    loading...
Cat. No.: HY-P701995
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PYHIN1; interferon-Inducible Protein X; Pyrin And HIN Domain Family Member 1; MGC23885; IFIX; Pyrin And HIN Domain Family, Member 1; Pyrin And HIN Domain-Containing Protein 1
Species:  
Human
Source:  
E. coli
loading...
    loading...
Cat. No.: HY-P702986
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: STAT2; Signal Transducer And Activator Of Transcription 2, 113kD; Signal Transducer And Activator Of Transcription 2; interferon Alpha Induced Transcriptional Activator; STAT113; Signal Transducer And Activator Of Transcription; Signal Transducer And Acti
Species:  
Human
Source:  
Sf9 insect cells
loading...
    loading...