387 Results for "

Chelating

" in MedChemExpress (MCE) Product Catalog:
Products (387)

387 Results for "Chelating" in MCE Product Catalog:

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1 Cited Publications
Cat. No.: HY-I0301
CAS No.: 90-80-2
Synonyms: Gluconic acid lactone
D-(+)-Glucono-1,5-lactone is a polyhydroxy (PHA) that is capable of metal chelating, moisturizing and antioxidant activity.
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1 Cited Publications
Cat. No.: HY-W030778
CAS No.: 139-13-9
Synonyms: Triglycollamic acid
Research Areas:  

Others

Nitrilotriacetic acid is an orally active chelating agent for metal ions. Nitrilotriacetic acid is an aminotricarboxylic acid that can sequester metal ions as water soluble complexes. Nitrilotriacetic acid reacts with strong oxidizing agents such as hypochlorite, chlorine, ozone, or oxygen in the presence of palladium/carbon catalyst. Nitrilotriacetic acid interacts with solid phases such as cell membranes and bone matrices in the mammalian system. Nitrilotriacetic acid is classified as an epigenetic rodent carcinogen .
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1 Cited Publications
Cat. No.: HY-W012037
CAS No.: 134-31-6
Synonyms: 8-Quinolinol hemisulfate
Research Areas:  

Infection

8-Hydroxyquinoline hemisulfate (8-Quinolinol hemisulfate) is a monoprotic bidentate chelating agent, exhibits antiseptic, disinfectant, and pesticide properties, functioning as a transcription inhibitor.
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1 Cited Publications
Cat. No.: HY-156780
CAS No.: 907958-80-9
Purity:  96.31%
Target:  

Cuproptosis

Research Areas:  

Cancer

NSC 689534 can form copper chelate with Cu 2+. NSC 689534/Cu 2+ complex is a potent oxidative stress inducer, and has antitumor activity .
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1 Cited Publications
Cat. No.: HY-125166
CAS No.: 544678-85-5
Purity:  99.33%
Target:  

MMP

Research Areas:  

Neurological Disease Cancer

DB04760 (compound 4) is a potent, highly selective, non-zinc-chelating MMP-13 inhibitor with an IC50 of 8 nM . DB04760 significantly reduces paclitaxel neurotoxicity and has anticancer activity .
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1 Cited Publications
Cat. No.: HY-134797
CAS No.: 1222468-90-7
Purity:  ≥98.0%
Research Areas:  

Cancer

P-SCN-Bn-deferoxamine is a bifunctional chelating agent that can link radioactive metal nuclides (such as Zr-89) and biological targeting molecules (such as antibodies). P-SCN-Bn-deferoxamine can be used for the research of immune PET imaging .
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1 Cited Publications
Cat. No.: HY-W127847
CAS No.: 5064-31-3
Synonyms: Triglycollamic acid trisodium salt
Nitrilotriacetic acid (Triglycollamic acid) trisodium salt is a chelating agent commonly used in various industrial processes, especially in the production of detergents, cleaners and metal plating solutions. Nitrilotriacetic acid trisodium salt has unique chemical properties that bind to metal ions, preventing them from reacting or precipitating out of solution.
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1 Cited Publications
Cat. No.: HY-B0302
CAS No.: 2809-21-4
Synonyms: Etidronate; HEDPA; HEDP
Etidronic acid (Etidronate) is an orally and intravenously active bisphosphonate. Etidronic acid inhibits resorption of bone, reduces arterial calcification and can be used for osteoporosis research. Etidronic acid has anticancer activity. Etidronic acid is a chelating agent and can be used to remove heavy metal in water .
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1 Cited Publications
Cat. No.: HY-B0302A
CAS No.: 7414-83-7
Synonyms: Etidronate disodium; HEDPA disodium; HEDP disodium
Target:  

Apoptosis

Research Areas:  

Metabolic Disease Cancer

Etidronic acid (Etidronate) disodium is an orally and intravenously active bisphosphonate. Etidronic acid disodium inhibits resorption of bone, reduces arterial calcification and can be used for osteoporosis research. Etidronic acid disodium has anticancer activity. Etidronic acid disodium is a chelating agent and can be used to remove heavy metal in water .
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1 Cited Publications
Cat. No.: HY-N0814A
CAS No.: 123408-98-0
Synonyms: Inositol hexaphosphate dodecasodium hydrate; SNF472 dodecasodium hydrate
Phytic acid (Inositol hexaphosphate) dodecasodium hydrate is a phosphorus storage compound of seeds and cereal grains. Phytic acid dodecasodium hydrate is known as a food inhibitor, which has a strong ability to chelate multivalent metal ions, specially zinc, calcium, iron and as with protein residue. Phytic acid dodecasodium hydrate inhibits the enzymatic superoxide source xanthine oxidase (XO), and has antioxidative, neuroprotective, anti-inflammatory effects .
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1 Cited Publications
Cat. No.: HY-W020215
CAS No.: 99-14-9
Tricarballylic acid is an orally active compound that can be produced by rumen microorganisms and has the activity of chelating magnesium. Tricarballylic acid is also a competitive inhibitor of aconitate hydratase, with a Ki value of 0.52 mM. Tricarballylic acid can inhibit the oxidation of acetate in the citric acid cycle and can be used in the research of ruminant tissue metabolism and grass tetany syndrome. In addition, Tricarballylic acid can be used to synthesize specific complexes and produce plasticizers .
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1 Cited Publications
Cat. No.: HY-108309
CAS No.: 1984-15-2
Purity:  ≥98.0%
Synonyms: Methylenediphosphonic acid
Research Areas:  

Others

Medronic acid (Methylenediphosphonic acid) is a methylene-substituted bisphosphonate. Medronic acid has an affinity for the surface of hydroxyapatite crystals in the bone matrix and adheres to them. Medronic acid can be used in complex with radioisotopes in bone imaging. Due to its strong metal chelating ability, medronic acid is also used as a water treatment chemical. In addition, medronic acid is used as a solvent additive to improve peak shape and signal of metal-sensitive metabolites in LC/MS analysis .
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1 Cited Publications
Cat. No.: HY-W006064
CAS No.: 23235-01-0
Synonyms: (S)-2-Aminopent-4-ynoic acid
Research Areas:  

Others

(S)-2-Aminopent-4-ynoic acid is a synthetic amino acid. (S)-2-Aminopent-4-ynoic acid can be used in synthesis of folate-conjugates and corresponding metal-chelate complexes . (S)-2-Aminopent-4-ynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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1 Cited Publications
Cat. No.: HY-W087028
CAS No.: 1338231-09-6
NOTA-NHS ester is a chelating agent. NOTA-NHS ester can be coupled with T140 (HY-P4810) to produce NOTA-T140. NOTA-T140 can be radiolabeled with Al[ 18F]. The uptake of Al[ 18F]NOTA-T140 in tumors is correlated with the expression level of CXCR4. Al[ 18F]NOTA-T140 can be used in tumor PET imaging studies. NOTA-NHS ester can be used for fluorescent labeling .
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1 Cited Publications
Cat. No.: HY-128890
CAS No.: 170908-81-3
Purity:  ≥95.0%
Research Areas:  

Cancer

DOTA-NHS-ester is a bifunctional reagent containing a DOTA chelating group and an NHS ester. DOTA-NHS-ester can be conjugated to proteins/antibodies/HSA via primary amino groups for radiolabeling with radiometals, and when combined with 16-amino-1-hexadecanethiol hydrochloride, it enables the construction of self-assembled monolayers on gold surfaces for lectin microarrays. DOTA-NHS-ester can be used to prepare DOTA-HSA-Z (HER2:342) imaging probes, as well as to construct Trop2-targeted radiotherapeutic and diagnostic probes for pancreatic cancer .
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1 Cited Publications
Cat. No.: HY-P10761
CAS No.: 2941391-49-5
DPI-4452 is a CAIX-targeting cyclic peptide with a DOTA cage, and can be chelated with radionuclide for CAIX-expressing tumor PET-CT imaging and study. DPI-4452 specifically and selectively binds CAIX without interaction with an in vitro off-target receptor panel of 55 targets (IC50 for recombinant hCAIX: 130 nM). Radiolabeled DPI-4452 inhibits tumor growth in HT-29 and SK-RC-52 xenograft mouse models . DPI-4452 can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
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1 Cited Publications
Cat. No.: HY-128890B
Purity:  95.00%
Research Areas:  

Cancer

DOTA-NHS-ester TFA is a bifunctional reagent containing a DOTA chelating group and an NHS ester. DOTA-NHS-ester TFA can be conjugated to proteins/antibodies/HSA via primary amino groups for radiolabeling with radiometals, and when combined with 16-amino-1-hexadecanethiol hydrochloride, it enables the construction of self-assembled monolayers on gold surfaces for lectin microarrays. DOTA-NHS-ester TFA can be used to prepare DOTA-HSA-Z (HER2:342) imaging probes, as well as to construct Trop2-targeted radiotherapeutic and diagnostic probes for pancreatic cancer .
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1 Cited Publications
Cat. No.: HY-W035903
CAS No.: 2002-24-6
Synonyms: 2-Aminoethanol hydrochloride
Ethanolamine hydrochloride, is an organic compound used in various industrial applications. It is a white or colorless solid that is soluble in water and has a faint odor. One of the major uses of Ethanolamine hydrochloride is in the production of detergents and surfactants. Used as a raw material in the manufacture of compounds such as ethylenediaminetetraacetic acid (EDTA) and diethanolamine, which are commonly used in household and industrial cleaning products. Ethanolamine hydrochloride is also used in the synthesis of pharmaceuticals, agrochemicals and rubber processing agents. It acts as a buffer in certain chemical reactions, helping to adjust pH and maintain stability. Ethanolamine hydrochloride can be used for gas purification and metal corrosion inhibitor. Its ability to react with acid gases such as carbon dioxide and sulfur dioxide makes it useful for removing impurities from natural gas and other industrial gases. Overall, Ethanolamine hydrochloride is a multifunctional compound with many potential industrial applications. Its ability to act as a buffer, chelating agent, and corrosion inhibitor makes it an important tool in a variety of industries.
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1 Cited Publications
Cat. No.: HY-W110883
CAS No.: 3618-43-7
Xylenol orange tetrasodium salt, IND is commonly used as a colorimetric indicator for metal titration and possesses Zn 2+ chelating activity. Xylenol orange tetrasodium salt, IND binds Zn 2+ under physiological pH, and its Zn-XO complex allows visual differentiation between tartrate and malate ions. Xylenol orange tetrasodium salt, IND undergoes decolorization upon oxidation by hydrogen peroxide, undergoes a Co (II)-catalyzed pseudo-second-order reaction in a strong alkaline environment, and regulates the ferrous ion oxidation process mediated by peroxy radicals. Xylenol orange tetrasodium salt, IND forms colored ternary complexes with various anions, cations and iron-alanine, which is suitable for spectrophotometric quantification and can also be used for alanine irradiation dose detection. Xylenol orange tetrasodium salt, IND is applicable to EDTA metal titration analysis under acidic conditions .
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Cat. No.: HY-134418
CAS No.: 56491-86-2
Purity:  ≥98.0%
NOTA is a bifunctional chelate which acts as the framework to construct PET imaging tools. NOTA also can be used for probe design and signal amplification via the multivalent effect. NOTA can be used in multiple myeloma, breast cancer, lymphoma and myocardial infarction research .
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