1. Metabolic Enzyme/Protease
  2. MMP
  3. DB04760

DB04760 

Cat. No.: HY-125166
Handling Instructions

DB04760 is a potent, highly selective, non-zinc-chelating matrix metalloproteinase (MMP)-13 inhibitor with an IC50 of 8 nM. MMPs are under investigation for the treatment of cancer, arthritis, and cardiovascular disease.

For research use only. We do not sell to patients.

DB04760 Chemical Structure

DB04760 Chemical Structure

CAS No. : 544678-85-5

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Description

DB04760 is a potent, highly selective, non-zinc-chelating matrix metalloproteinase (MMP)-13 inhibitor with an IC50 of 8 nM. MMPs are under investigation for the treatment of cancer, arthritis, and cardiovascular disease[1].

IC50 & Target[1]

MMP-13

8 nM (IC50)

Molecular Weight

410.42

Formula

C₂₂H₂₀F₂N₄O₂

CAS No.

544678-85-5

SMILES

FC1=C(C=C(C=C1)CNC(C2=CC(C(NCC3=CC=C(C(C)=C3)F)=O)=NC=N2)=O)C

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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This equation is commonly abbreviated as: C1V1 = C2V2

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DB04760
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