1. Metabolic Enzyme/Protease
  2. MMP
  3. DB04760

DB04760 

Cat. No.: HY-125166
Handling Instructions

DB04760 (compound 4) is a potent, highly selective, non-zinc-chelating MMP-13 inhibitor with an IC50 of 8 nM. DB04760 significantly reduces paclitaxel neurotoxicity and has anticancer activity.

For research use only. We do not sell to patients.

DB04760 Chemical Structure

DB04760 Chemical Structure

CAS No. : 544678-85-5

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Description

DB04760 (compound 4) is a potent, highly selective, non-zinc-chelating MMP-13 inhibitor with an IC50 of 8 nM[1]. DB04760 significantly reduces paclitaxel neurotoxicity and has anticancer activity[2].

IC50 & Target[1]

MMP-13

8 nM (IC50)

Molecular Weight

410.42

Formula

C₂₂H₂₀F₂N₄O₂

CAS No.

544678-85-5

SMILES

FC1=C(C=C(C=C1)CNC(C2=CC(C(NCC3=CC=C(C(C)=C3)F)=O)=NC=N2)=O)C

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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DB04760
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HY-125166
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