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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
58 Results for "
SW-480
" in MedChemExpress (MCE) Product Catalog:
Products (58)
58 Results for "SW-480" in MCE Product Catalog:
Cat. No.: HY-109049R
CAS No.: 1467093-03-3
Synonyms: SM04690 (Standard); Lorecivivint (Standard)
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Research Areas:
Adavivint (Standard) is the analytical standard of Adavivint (HY-109049). This product is intended for research and analytical applications. Adavivint (SM04690; Lorecivivint) is a potent and selective inhibitor of canonical Wnt signaling, with an EC50 of 19.5 nM via a high-throughput TCF/LEF-reporter assay in SW480 colon cancer cells .
Cat. No.: HY-N16817
CAS No.: 155969-82-7
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Cat. No.: HY-180537
Apoptosis inducer 57 is a apoptosis inducer and Thymidylate Synthase (TS) inhibitor. Apoptosis inducer 57 exhibits cytotoxic activity against SW480 and MCF-7 cancer cells with IC50 values of 15.7 and 16.5 µM, and induces dose-dependent apoptosis and S-phase cell cycle arrest. Apoptosis inducer 57 stalely binds the TS active site via interactions with Asp218 and Met311. TS-IN-9 can be used for breast cancer and colorectal cancer research .
Cat. No.: HY-N17603
CAS No.: 76746-56-0
Synonyms: Acertannin
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Cat. No.: HY-119590
CAS No.: 31501-55-0
Synonyms: Lonchocarpine
Cat. No.: HY-179151
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Research Areas:
CDK4/6-IN-26 is a carbamate derivative that targets CDK4/CDK6. CDK4/6-IN-26 reduces CDK4/CDK6 levels, resulting in cell cycle arrest in the G0/G1 phase and in the S phase. CDK4/6-IN-26 exhibits high potency against SW480 cells (IC50 = 6.3 μM). CDK4/6-IN-26 affects ROS levels by increasing the expression of SOD2/MnSOD. CDK4/6-IN-26 establishes several interactions with the amino acids of the CDK6 active site. CDK4/6-IN-26 can be used for the research of colorectal cancer .
Cat. No.: HY-N15612
CAS No.: 23053-61-4
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Cat. No.: HY-N13800
CAS No.: 1800008-77-8
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Cat. No.: HY-N19850
CAS No.: 98216-05-8
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Cat. No.: HY-N19852
CAS No.: 111321-13-2
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Cat. No.: HY-181448
Synonyms: Inositol hexaphosphate hexalithium; SNF472 hexalithium
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Research Areas:
Cardiovascular Disease Neurological Disease Metabolic Disease Cancer
Phytic acid (Inositol hexaphosphate hexalithium) hexalithium is an orally active compound. Phytic acid hexalithium can be derived from the seeds of legumes. Phytic acid is a [PO4] 3- storage depot and precursor for other inositol phosphates and pyrophosphates. Phytic acid hexalithium attenuates Aβ oligomers and upregulates Autophagy protein. Phytic acid hexalithium can be used in cardiovascular disease, metabolic disease, nervous system disease and cancer research .
Cat. No.: HY-183801
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Cu2LCl2(H2O) acts as a proteasome inhibitor and protein tyrosine phosphatase inhibitor, with antiproliferative and apoptosis-inducing effects. Cu2LCl2(H2O) exhibits low cytotoxicity against normal cells and remarkable in vivo antitumor efficacy. Cu2LCl2(H2O) inhibits proteasome activity in colon cancer cells, and suppresses PTP1B and TCPTP activities in breast cancer cells. Cu2LCl2(H2O) can be used in the research of colon cancer, breast cancer and liver cancer .
Cat. No.: HY-N21741
CAS No.: 957201-53-5
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Cat. No.: HY-N13833
CAS No.: 2188162-94-7
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Cat. No.: HY-W420454
CAS No.: 100414-80-0
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Cat. No.: HY-D3352
CAS No.: 1081979-12-5
Synonyms: AGSCYCSGPPRFECWCYETEGT-Cy5
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
