491 Results for "

contraction

" in MedChemExpress (MCE) Product Catalog:
Products (491)

491 Results for "contraction" in MCE Product Catalog:

Cat. No.: HY-P1564A
CAS No.: 2918768-31-5
Target:  

Angiotensin Receptor

Research Areas:  

Others

[Sar1, Ile8]-Angiotensin II (TFA) is a peptide that has multiple effects on vascular smooth muscle, including contraction of normal arteries and hypertrophy or hyperplasia of cultured cells or diseased vessels.
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Cat. No.: HY-W127502
CAS No.: 52603-03-9
Synonyms: 1-Hexadecyl LPA; 1-Palmityl LPA; LPA O-16:0
1-Hexadecyl lysophosphatidic acid is an ether analog of lysophosphatidic acid (LPA) containing a hexadecyl group in the sn-1 position. LPA binds to five different G protein-coupled receptors and mediates a variety of biological responses, including cell proliferation, smooth muscle contraction, platelet aggregation, neurite contraction, and cell motility.
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Cat. No.: HY-P3092
CAS No.: 26145-48-2
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease

Phyllomedusin, an tachykinin decapeptide, is a NK1 receptor agonist. Phyllomedusin has vasodilating activity and provokes the contraction of the pylorus .
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Cat. No.: HY-P2734
CAS No.: 9032-10-4
Target:  

Phosphatase

Research Areas:  

Others

Phosphorylase a, rabbit muscle is glycogen phosphorylase isolated from rabbit muscle. Phosphorylase a, rabbit muscle catalyzes glycogenolysis, converting glycogen and inorganic phosphate into glucose-1-phosphate to supply energy for muscle contraction .
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Cat. No.: HY-W983015
CAS No.: 23130-26-9
Davidigenin is an antidiabetic compound with antitumor, antispasmodic, and antioxidant activities. Davidigenin inhibits duodenal contractions induced by acetylcholine or histamine.
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Cat. No.: HY-P3652
CAS No.: 67256-27-3
Research Areas:  

Metabolic Disease

Cholecystokinin-33 (swine) is a cholecystokinin (CCK) fragment. Cholecystokinin-33 (swine) can reduce food intake and gallbladder contraction .
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Cat. No.: HY-N7527
CAS No.: 57672-79-4
Baccatin VI is a natural taxoid with antinociceptive activities. Baccatin VI possesses significant antinociceptive activity against p-Benzoquinone-induced abdominal contractions .
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Cat. No.: HY-P3847
CAS No.: 131019-53-9
Synonyms: Tyr-NKB
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease

Tyr0-Neurokinin B (Tyr-NKB) is an analogue of Neurokinin B. Tyr0-Neurokinin B can exerts contractions in bladder .
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Cat. No.: HY-106234
CAS No.: 383123-18-0
ZP 120C is a potent and partial ORL1 receptor agonist. ZP 120C inhibits electrically induced contraction. ZP 120C can be used in the research of hyponatremia/hypokalemia .
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Cat. No.: HY-P3563
CAS No.: 1219444-22-0
Target:  

Endothelin Receptor

Research Areas:  

Cardiovascular Disease

[Lys4] Sarafotoxin S6c, a sarafotoxin analogue, is a potent and partial agonist of endothelin receptor. [Lys4] Sarafotoxin S6c elicits contraction of pig coronary artery, with an EC50 of 1.5 nM .
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Cat. No.: HY-P1541
CAS No.: 85490-53-5
Synonyms: Motilin (canine)
Target:  

Motilin Receptor

Research Areas:  

Metabolic Disease

Motilin, canine is a 22-amino acid peptide. Motilin is a potent agonist for gastrointestinal smooth muscle contraction.
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Cat. No.: HY-P10979
CAS No.: 116786-35-7
Research Areas:  

Neurological Disease

Buccalin is a neuropeptide that colocalizes with small molecule cardioactive peptides in neuronal B15. When exogenously applied to the ARC neuromuscular junction, Buccalin reduces the amplitude of muscle contraction induced by motor neuron firing and acts only presynaptically. Buccalin has no effect on the rate of muscle relaxation and reduces motor neuron-induced ARC excitatory junction potentials without affecting contraction produced by direct acetylcholine action on the muscle .
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Cat. No.: HY-120927A
CAS No.: 170098-43-8
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

Alvimopan metabolite hydrochloride is a peripherally restricted Opioid Receptor antagonist that inhibits the amplitude of electrically evoked contractions and spontaneous mechanical activity in guinea pig ileum .
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Cat. No.: HY-148533
CAS No.: 2772700-36-2
Research Areas:  

Neurological Disease

β2AR agonist /M-receptor antagonist-1 is a potent dual muscarinic antagonist/beta 2 agonist (MABA). β2AR agonist /M-receptor antagonist-1 potently relaxes either Carbachol?(HY-B1208)-induced contraction, in the absence (MABA) or presence of Propranolol?(HY-B1208), or Histamine(HY-B1204)-induced contraction (β2) .
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Cat. No.: HY-120473
CAS No.: 1192348-73-4
Target:  

Adrenergic Receptor

Research Areas:  

Metabolic Disease

TAK-259 is an orally active α1D-adrenergic receptor antagonist with a Ki value of 1.1 nM for human α1D-adrenergic receptors. TAK-259 can inhibit the contraction of isolated bladder strips in rats with bladder outlet obstruction, reduce non-voiding bladder contractions, and improve urinary frequency symptoms. TAK-259 can be used in research related to overactive bladder .
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Cat. No.: HY-103182A
CAS No.: 409344-71-4
Target:  

Adenosine Receptor

Research Areas:  

Others

PSB-1115 potassium salt is a selective A2B Adenosine Receptor antagonist. PSB-1115 potassium salt inhibits the 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced contraction inhibition of acetylcholine (ACh) .
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Cat. No.: HY-P3853
CAS No.: 141663-86-7
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease

GR 87389 is a potent NK2 receptor antagonist. GR 87389 antagonized GA 64349-induced smooth muscle strips contractions in a competitive manner in the human detrusor, prostate and prostatic urethra .
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Cat. No.: HY-U00135
CAS No.: 136941-70-3
Target:  

Calcium Channel

Research Areas:  

Cardiovascular Disease

Calcium channel-modulator-1 is an orally active calcium channel modulator that blocks aortic contraction with an IC50 of 0.8 μM. Calcium channel-modulator-1 can be used for the study of cardiovascular conditions .
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Cat. No.: HY-114743
CAS No.: 149440-36-8
Research Areas:  

Others

GS 283 is a compound with calcium antagonist and weak histamine and muscarinic receptor blocking activity, with activity in modulating contraction of guinea pig and rat tracheal smooth muscle. GS 283 inhibits contractions induced by carbachol, histamine (guinea pig only), and high H + in guinea pig and rat tracheal smooth muscle, inhibits Ca 2+-induced contractions in guinea pig tracheal smooth muscle, and at high concentrations completely abolishes contractions induced by carbachol in Ca 2+-free medium.
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Cat. No.: HY-P2084
CAS No.: 149665-72-5
Target:  

Inhibitory Antibodies

Research Areas:  

Neurological Disease

WWamide-1 is a neuropeptide, which can be isolated form Achatina fulica. WWamide-1 inhibits central neurons of snails, regulates the snail muscle contraction. WWamide-1 inhibits the contraction of anterior byssus retractor muscle (ABRM), enhances the contraction of the radular traction muscle, through effects on presynaptic and postsynaptic membrane of the muscle .
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