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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
459 Results for "
PROTAC compound
" in MedChemExpress (MCE) Product Catalog:
Products (459)
459 Results for "PROTAC compound" in MCE Product Catalog:
Cat. No.: HY-168229
CAS No.: 2410314-57-5
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PROTAC SMARCA2 degrader-27 (compound 4) is a PROTAC SMARCA2 degrader. PROTAC SMARCA2 degrader-27 has the potential to be used in cancer research .
Cat. No.: HY-169271
CAS No.: 2660324-41-2
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PROTAC SMARCA2 degrader-20 (Compound I-40) is a PROTAC SMARCA2 degrader. PROTAC SMARCA2 degrader-20 has the potential for the research of cancer .
Cat. No.: HY-141486A
CAS No.: 2661609-57-8
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PROTAC PARP/EGFR ligand 1 is an active compound that can be used for the synthesis of dual PARP EGFR degraders by proteolytic targeting chimera (PROTAC) technology .
Cat. No.: HY-169273
CAS No.: 2760246-90-8
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PROTAC SMARCA2 degrader-22 (Compound 5) is a PROTAC degrader for SMARCA2 with a degradation efficacy of 94% at 100 nM. PROTAC SMARCA2 degrader-22 inhibits the proliferation of cell A549 with an EC50 < 250 nM .
Cat. No.: HY-177019
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(S,R,S)-AHPC-PEG3-ADIBO-adipic acid (Compound 2a) is a PROTAC ligand (Compound 1d)-linker conjugate. (S,R,S)-AHPC-PEG3-ADIBO-adipic acid can be coupled with aptamer to construct PROTAC .
Cat. No.: HY-115729A
CAS No.: 2411021-95-7
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(R)-PROTAC CDK9 ligand-1 (Compound 19.4) is a CDK9-targeting degrader that can be used to synthesize PROTAC with antitumor activity .
Cat. No.: HY-168236
CAS No.: 2641510-88-3
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PROTAC SMARCA2 degrader-28 (Compound 158) is a PROTAC degrader for SMARCA2, that degrades SMARCA2 with a DC50 of 3 nM in HiBiT A549 cells .
Cat. No.: HY-147654
CAS No.: 3031330-66-9
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PROTAC Hemagglutinin Degrader-1 (Compound V3) is a potent PROTAC influenza hemagglutinin (HA) degrader with a median degradation concentration of 1.44 μM. PROTAC Hemagglutinin Degrader-1 shows broad-spectrum anti-influenza virus activity .
Cat. No.: HY-169275
CAS No.: 2755761-70-5
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PROTAC SMARCA2 degrader-24 (Compound 34) is a PROTAC degrader for SMARCA2 with a DC50 < 0.1 µM in HeLa. PROTAC SMARCA2 degrader-24 degrades SMARCA4 with a DC50 > 10 μM in HeLa .
Cat. No.: HY-176390
CAS No.: 1577212-91-9
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Adamantan-C-amide-PEG2-C2-amine (Compound 8) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs, such as PROTAC β-NF-JQ1 (HY-130256) .
Cat. No.: HY-160563
CAS No.: 3025533-68-7
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PROTAC ERα Degrader-8 (compound ii-56) is a potent PROTAC degrader of Erα, with DC50 of 0.000006 μM in MCF7 cells .
Cat. No.: HY-148834
CAS No.: 2154342-57-9
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Pomalidomide-piperazine is an active compound that can be used to synthesis the E3 ligand for PROTAC .
Cat. No.: HY-162949
CAS No.: 1098625-76-3
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Piperidin-4-amine-C5-O-C1 is a PROTAC (compound D4; HY-168037) linker used in the synthesis of PROTACs .
Cat. No.: HY-W249500
CAS No.: 2377643-33-7
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2-Methoxyphenyl dihydrouracil (Compound 13) is a CRBN ligand, and can be used for synthesis of PROTACs .
Cat. No.: HY-169278
CAS No.: 2760247-27-4
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PROTAC SMARCA2 degrader-26 (compound 45) is a potent SMARCA2 PROTAC degrader. PROTAC SMARCA2 degrader-26 induces SMARCA2 and SMARCA4 degradation in VCaP cells with the percent degradation of 94% and 57% for SMARCA2 and SMARCA4, respectively. PROTAC SMARCA2 degrader-26 shows antiproliferative activity .
Cat. No.: HY-164925
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ER ligand-4 (compound 45a) is an PROTAC target protein ligand of HY-164924 .
Cat. No.: HY-170340
CAS No.: 2504911-73-1
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PROTAC ER Degrader-14 (compound 86) is a PTORAC-type Estrogen Receptor/ERR degrader .
Cat. No.: HY-169270
CAS No.: 2567913-00-0
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PROTAC SMARCA2 degrader-19 (Compound 46) is a PROTAC degrader for SMARCA2, that degrades SMARCA2 in cell A549 and MV411 with a DC50 < 100 nM. PROTAC SMARCA2 degrader-19 degrades SMARCA4 in cell MV411 with a DC50 > 1000 nM .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
