PROTAC SMARCA2 degrader-19
PROTAC SMARCA2 degrader-19 (Compound 46) is a PROTAC degrader for SMARCA2, that degrades SMARCA2 in cell A549 and MV411 with a DC50 < 100 nM. PROTAC SMARCA2 degrader-19 degrades SMARCA4 in cell MV411 with a DC50 > 1000 nM.
For research use only. We do not sell to patients.
- CAS No.: 2567913-00-0
- Formula: C50H58N10O5S
- Molecular Weight:911.12
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 2567913-00-0
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Molecular Weight 911.12
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Formula C50H58N10O5S
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SMILES
OC1=C(C=CC=C1)C2=NN=C3NC=C(C4CCN(C5=NC=C([C@@H]6CC[C@H](CC6)C(N[C@@H](C(C)(C)C)C(N7[C@@H](C[C@H](C7)O)C(NCC8=CC=C(C9=C(C)N=CS9)C=C8)=O)=O)=O)C=N5)CC4)C3=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)