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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
70 Results for "
Pregnane
" in MedChemExpress (MCE) Product Catalog:
Products (70)
70 Results for "Pregnane" in MCE Product Catalog:
Cat. No.: HY-182582
CAS No.: 1430210-54-0
Research Areas:
ZY12201 is a selective and orally active TGR5 agonist and pan-CYP inhibitor. ZY12201 lowers glucose levels. ZY12201 induces enzymes regulated through Aryl Hydrocarbon Receptor, Constitutive Androstane Receptor, and Pregnane X Receptor. ZY12201 can be used for the research of type 2 diabetes .
Cat. No.: HY-N21545
CAS No.: 154022-56-7
Category:
Target:
Cat. No.: HY-103244R
CAS No.: 338404-52-7
Target:
Research Areas:
CITCO (Standard) is the analytical standard of CITCO (HY-103244). This product is intended for research and analytical applications. CITCO, an imidazothiazole derivative, is a selective Constitutive androstane receptor (CAR) agonist. CITCO inhibits growth and expansion of brain tumour stem cells (BTSCs) and has an EC50 of 49 nM over pregnane X receptor (PXR), and no activity on other nuclear receptors .
Cat. No.: HY-100793R
CAS No.: 126411-39-0
Synonyms: GW 485801 (Standard)
Research Areas:
SR12813 (Standard) is the analytical standard of SR12813 (HY-100793). This product is intended for research and analytical applications. SR12813 (GW 485801) is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, with an IC50 value of 0.85 μM . SR12813 is also an efficient agonist of human pregnane X receptor (hPXR). SR12813 can strongly bind to hPXR but not to mouse PXR (mPXR) .
Cat. No.: HY-N19818
CAS No.: 2088505-67-1
Cat. No.: HY-111828R
CAS No.: 953778-63-7
Target:
Research Areas:
TTA-A2 (Standard) is the analytical standard of TTA-A2 (HY-111828). This product is intended for research and analytical applications. TTA-A2 is a potent, selective and orally active t-type voltage gated calcium channel antagonist with reduced pregnane X receptor (PXR) activation. TTA-A2 is equally potent against the Cav3.1 (a1G) and Cav3.2 (a1H) channels with IC50 values of 89 nM and 92 nM, respectively, at -80 and -100 mV holding potentials. TTA-A2 can be used for the research of a variety of human neurological diseases, including sleep disorders and epilepsy .
Cat. No.: HY-P701396
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: NR1I2; Steroid And Xenobiotic Receptor; Nuclear Receptor Subfamily 1 Group I Member 2; Orphan Nuclear Receptor PAR1; Orphan Nuclear Receptor PXR; Nuclear Receptor Subfamily 1, Group I, Member 2; Pregnane X Receptor; PARq; PAR2; PAR1; SXR; SAR; PXR; PRR; O
Species:
Human
Source:
E. coli
Cat. No.: HY-P701397
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: NR1I2; Steroid And Xenobiotic Receptor; Nuclear Receptor Subfamily 1 Group I Member 2; Orphan Nuclear Receptor PAR1; Orphan Nuclear Receptor PXR; Nuclear Receptor Subfamily 1, Group I, Member 2; Pregnane X Receptor; PARq; PAR2; PAR1; SXR; SAR; PXR; PRR; O
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
