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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
168 Results for "
Dogs
" in MedChemExpress (MCE) Product Catalog:
Products (168)
168 Results for "Dogs" in MCE Product Catalog:
Cat. No.: HY-168792
CAS No.: 56469-26-2
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(±)-9-Nor-9α-hydroxy Hexahydrocannabinol is a cannabinoid-type compound that has strong cannabinoid-like activity in both dogs and mice .
Cat. No.: HY-114682A
CAS No.: 24677-86-9
Synonyms: AHR 2277
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Lenperone hydrochloride (AHR 2277) is an antipsychotic compound and a dopamine antagonist. Lenperone hydrochloride reduces gastroesophageal sphincter pressure of healthy dogs. Lenperone hydrochloride can be used for neurological disease research .
Cat. No.: HY-W019720
CAS No.: 22661-87-6
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1-Methylguanidine hydrochloride is a uremic toxin, which accumulate in dogs with renal failure and chronic kidney disese. 1-Methylguanidine hydrochloride enhances the oxidative metabolism and induces apoptosis in neutrophils .
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Haloperidide (R3201) is a neuroleptic compound. Haloperidide is a potent and selective anti-emetic agent. Haloperidide antagonizes Apomorphine (HY-12723)-induced emesis in dogs .
Synonyms: K 5407 free base
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Nafetolol (K 5407 free base) is a β1-selective blocker with high hepatic clearance in humans and dogs, and undergoes extrahepatic, high-level metabolism .
Cat. No.: HY-B0519C
CAS No.: 11034-63-2
Tylosin (lactate) is an anti-bacterial agent that can target spore-forming bacteria. Tylosin (lactate) can increase the levels of Enterococcus and lactobacilli in dogs' feces and help relieve tylosin-responsive diarrhea .
Cat. No.: HY-129782
CAS No.: 179464-49-4
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SC-55858 is an effective superoxide dismutase simulator. SC-55858 increased heart rate and decreased mean arterial pressure and left ventricular systolic and end-diastolic pressures in conscious dogs .
Cat. No.: HY-102092
CAS No.: 142375-60-8
Synonyms: PD 147953
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FR139317 (PD 147953) is a selective ETA receptor antagonist. FR139317 inhibits cerebral activation by intraventricular endothelin-1 in conscious rats. FR139317 also ameliorates cerebral vasospasm in dogs .
Cat. No.: HY-118033
CAS No.: 121995-36-6
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SQ 30774 is a renin (renin) inhibitor. SQ 30774 has potent in vitro inhibitory effects in primates but not in rats, pigs, or dogs. And imidazolinol renin inhibitors also inhibit PRA and reduce arterial blood pressure in vivo .
Cat. No.: HY-118311
CAS No.: 63250-48-6
Synonyms: (Z)-Probilin; (Z)-Secrebil; (Z)-Piprozolin
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(Z)-W 3699 is a potential choleretic. (Z)-W 3699 can increase the solubility of cholesterol in the gallbladder by altering the secretion of micellar bile acids. (Z)-W 3699 can prevent the formation of cholesterol-containing gallstones in dogs.
Cat. No.: HY-106932
CAS No.: 146144-48-1
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L-734217 is an orally active and potent fibrinogen receptor antagonist and an antithrombotic agent. L-734217 is excreted largely by the renal route and partly into the bile in dogs. L-734217 is promising for research of thrombotic disorders .
Cat. No.: HY-119064
CAS No.: 85493-98-7
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L-645164 is a potent inhibitor of hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase. L-645164 produces substantial decreases in circulating serum cholesterol concentrations in dogs. L-645164 is promising for research of central nervous system disorders .
Cat. No.: HY-P99579
CAS No.: 1608122-71-9
Synonyms: AT-005
Cat. No.: HY-126762
CAS No.: 69381-94-8
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Fenprostalene is an analog of Dinoprost (PGF2α) (HY-12956) that is used in veterinary medicine to induce corpus luteum regression and blood Progesterone (HY-N0437) levels reduction in dogs. Fenprostalene is potent in ameliorating pyometra and inducing abortion .
Cat. No.: HY-10420
CAS No.: 89592-45-0
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ZK-93426 is a benzodiazepine receptor antagonist. ZK-93426 does not alter the dogs' motility but induces generalized myoclonic jerks and tonic-clonic seizures. ZK-93426 can be used to study the mechanism of withdrawal reactions in the state of benzodiazepine dependence .
Cat. No.: HY-123284
CAS No.: 86315-69-7
LY137150 (2) and LY163252 (4) are products of LY175326 metabolism in rats or dogs. The preparation of LY175326 labeled with 14C at the methylthiol group provides a sensitive method to determine whether the metabolically produced LY137150 (2) is further metabolized by S-demethylation.
Cat. No.: HY-126044
CAS No.: 368451-07-4
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6-Hydroxy bexarotene is the main circulating metabolite of bexarotene, found in rats, dogs, and humans. Compared to the parent compound, 6-hydroxy-bexarotene shows a significantly reduced ability to bind to retinoid receptors and exhibits very minimal activity in activating retinoic acid receptors .
Cat. No.: HY-12159
CAS No.: 865110-07-2
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MK-0668 is an amino acid-based, potent antagonist of unactivated VLA-4, with an IC50) of 0.13 nM in human whole blood. And MK-0668 exhibits IC50s of 0.19 nM in dogs, 0.21 nM in rhesus monkeys, and 0.4 nM in rats .
Cat. No.: HY-12159A
CAS No.: 865111-04-2
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MK-0668 mesylate is an amino acid-based, potent antagonist of unactivated VLA-4, with an IC50) of 0.13 nM in human whole blood. And MK-0668 mesylate exhibits IC50s of 0.19 nM in dogs, 0.21 nM in rhesus monkeys, and 0.4 nM in rats .
Cat. No.: HY-12944
CAS No.: 716354-04-0
GSK163929 (compound 122) is an orally active, anti-HIV CCR5 antagonist with low inhibitory potency against hEGR. GSK163929 had no adverse effects in rats at 2000 mg/kg/day (i.v., 7 d) and in dogs at 250 mg/kg/day (i.v., 7 d) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
