2. Inhibitory Antibodies
  3. Tamtuvetmab

Tamtuvetmab  (Synonyms: AT-005; AT005)

Cat. No.: HY-P99579

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Tamtuvetmab (AT-005) is a caninised blontuvetmab against CD52. Tamtuvetmab increases progression-free survival (PFS), exhibits in vivo efficacy in dogs with naïve T-cell lymphoma (LSA). Tamtuvetmab has been approved by veterinary.

For research use only. We do not sell to patients.

Tamtuvetmab Chemical Structure

Tamtuvetmab Chemical Structure

CAS No. : 1608122-71-9

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Tamtuvetmab Related Antibodies

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Description

Tamtuvetmab (AT-005) is a caninised blontuvetmab against CD52. Tamtuvetmab increases progression-free survival (PFS), exhibits in vivo efficacy in dogs with naïve T-cell lymphoma (LSA). Tamtuvetmab has been approved by veterinary[1][2].

IC50 & Target

CD52[1]
In Vivo

Tamtuvetmab (5 mg/mL, 7.5-30 mL; i.v.; 15-30 min) has in vivo efficacy in dogs with naïve T-cell lymphoma (LSA), but resulting in vomiting, weight loss, diarrhoea, lethargy, decreased appetite and anorexia[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: T-cell LSA Model in Dog[1]
Dosage: 5 mg/mL, 7.5-30 mL; Dogs weighing for 2-15 kg received 7.5 mL, for 15.1-30 kg received 15 mL, for 30.1-45 kg received 22.5 mL, for 45.1-60 kg received 30 mL
Administration: Intravenous injection; 15-30 min
Result: Showed in vivo efficacy with severe side effect.
CAS No.
SMILES

[Tamtuvetmab]
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tamtuvetmab1608122-71-9AT-005 AT005AT005AT 005OthersInhibitorinhibitorinhibit

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