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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
135 Results for "
IMP
" in MedChemExpress (MCE) Product Catalog:
Products (135)
135 Results for "IMP" in MCE Product Catalog:
Cat. No.: HY-168500
CAS No.: 2058069-25-1
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Metallo-β-lactamase-IN-16 (compound 18) is a sulfone containing metallo-β-lactamase inhibitor with an anti-bacterial activity. Metallo-β-lactamase-IN-16 inhibits NDM-1 (New Dehli metallo-β-lactamase-1), IMP-1 (imipenemase-1), VIM-1 (Verona integron-encoded metallo-β-lactamase), and VIM-2 with IC50 values of 0.16 nM, 0.23 nM, 0.31 nM and 1.0 nM, respectively .
Cat. No.: HY-173472
CAS No.: 2876921-34-3
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MBL-IN-5 is a metallo-β-lactamase (MBL) inhibitor. MBL-IN-5 inhibits three clinically relevant B1 subfamily MBLs (NDM-1, VIM-1, and IMP-1) with IC50s of 0.05 nM, 14 nM and 21 nM respectively. MBL-IN-5 remarkably enhances carbapenems’ effectiveness against MBL-producing clinical strains and significantly reduces the bacterial load in a neutropenic murine thigh infection model combined with the IPM antibiotic .
Cat. No.: HY-10250A
Purity: 99.82%
Synonyms: TCN-P sodium
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Triciribine phosphate sodium inhibits amidophosphoribosyltransferase by an allosteric mechanism which affects the first committed step of de novo purine biosynthesis. Triciribine phosphate sodium also inhibits IMP dehydrogenase which is the first committed step of guanosine nucleotide synthesis. Tricilibine phosphate does not affect ligase activity .
Cat. No.: HY-113590
CAS No.: 1019207-72-7
FR295389 is a dihydroimidazopyrazolium cephalosporin with antibacterial activity. FR295389 shows activity against IMP-type metallo-β-lactamases (MBL)-producing Klebsiella pneumoniae, Acinetobacter baumanii and Pseudomonas putida with MIC values ranging from 4 to 32 mg/mL .
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Cat. No.: HY-208743
CAS No.: 2383117-97-1
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IMP-1711 is a stereoselective UCHL1 negative control agent. IMP-1711 serves as a negative control for IMP-1710 (HY-138995) .
Cat. No.: HY-134199
CAS No.: 2059148-58-0
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IMP-1002 is a Plasmodium N-myristoyltransferase (NMT) inhibitor. IMP-1002 inhibits myristoylation activity, blocks parasite development. IMP-1002 can be used for the research of malaria .
Cat. No.: HY-126258
CAS No.: 1458674-25-3
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IMP-1700 is a potent DNA damage potentiator and antibacterial agent. IMP-1700 inhibits the bacterial SOS response to DNA damage. IMP-1700 potently sensitizes MRSA to Ciprofloxacin (HY-B0356) with an EC50 of 5.9 nM. IMP-1700 inhibits the growth of E. coli K-12 BW25113, S. aureus SH1000 and MRSA USA300 JE2 .
Cat. No.: HY-184152
CAS No.: 3129690-90-7
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IMP-2552 is a RAB27A/B inhibitor. IMP-2552 acts on the RAB27A/B effector protein-protein interaction, selectively modifying RAB27A/B-Cys123, but has no activity against RAB27A-Cys188. IMP-2552 can be used for the research of cancer .
Cat. No.: HY-184153
CAS No.: 3129691-65-9
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IMP-2958 is an inactive enantiomeric negative control probe with significantly reduced binding to RAB27A/B-Cys123.IMP-2958 serves as a negative control probe for off-target binding in phenotypic assays related to RAB27A/B studies.IMP-2958 functions as a control for stereoselective targeted covalent inhibitors of the RAB27-effector protein-protein interaction .
Cat. No.: HY-181923
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IMP-Zn is a pyrazole-hydrazone Schiff base zinc (II) complex. IMP-Zn exhibits significant antiproliferative activity against human colorectal cancer cells and induces cell cycle arrest. IMP-Zn shows stronger binding affinity than its free ligand IMP towards three cancer-related protein targets: EGFR kinase 1M17, cytochrome P450 3RUK, and CDK inhibitor 6GUE. IMP-Zn can be used in studies related to colorectal cancer .
Cat. No.: HY-RS17960
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Imp3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Imp3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS20755
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Imp4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Imp4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS27267
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Imp4 Rat Pre-designed siRNA Set A contains three designed siRNAs for Imp4 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-W769319A
Synonyms: 5'-IMP-13C5 TEA; IMP-13C5 TEA; Inosine 5'-dihydrogen phosphate-13C5 TEA
Cat. No.: HY-103056R
CAS No.: 1215010-55-1
Synonyms: IMP-366 (Standard)
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DDD85646 (Standard) is the analytical standard of DDD85646 (HY-103056). This product is intended for research and analytical applications. DDD85646 (IMP-366) is an orally active of trypanosoma brucei N-myristoyltransferase (TbNMT IC50=2 nM; hNMT IC50=4 nM). The enzyme N-myristoyltransferase (NMT) is a potential agent target for human African trypanosomiasis .
Cat. No.: HY-P701535
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BRAP; RING-Type E3 Ubiquitin Transferase BRAP2; BRCA1 Associated Protein; BRCA1-Associated Protein; BRAP2; Renal Carcinoma Antigen NY-REN-63; IMPedes Mitogenic Signal Propagation; Galectin-2-Binding Protein; RNF52; RING Finger Protein 52; IMP
Species:
Human
Source:
E. coli
Cat. No.: HY-RS18746
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Brap Mouse Pre-designed siRNA Set A contains three designed siRNAs for Brap gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-131965
CAS No.: 105828-41-9
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Imidacloprid impurity 1 (IMP-2) is the impurity found during the synthesis of Ivermectin (HY-15310) .
Cat. No.: HY-W002684
CAS No.: 3972-36-9
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(S)-2-Benzylsuccinic acid is an intermediate of KAD-1229 (HY-B0682A). (S)-2-Benzylsuccinic acid exerts weak inhibitory activity against IMP-1 metallo-β-lactamase .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
