Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
94 Results for "
18F
" in MedChemExpress (MCE) Product Catalog:
Products (94)
94 Results for "18F" in MCE Product Catalog:
Cat. No.: HY-P11859
Research Areas:
Cat. No.: HY-149219
CAS No.: 2716871-93-9
Target:
Research Areas:
BIBD-124 binds amyloid beta (Aβ) plaque with an IC50 value of 9.51 nM. [18F]BIBD-124 can be used as radiotracer of Aβ plaques .
Cat. No.: HY-113837
CAS No.: 1070878-63-5
Research Areas:
Flortanidazole is a derivative of 2-Nitroimidazole (HY-N0195). Under hypoxic conditions, Flortanidazole accumulates in hypoxic tissues through the reduction of 2-nitroimidazole and the retention of reactive intermediates by viable hypoxic cells. Flortanidazole binds to intracellular macromolecules under hypoxic conditions, thereby enabling quantification of tumor hypoxia. [ 18F]Flortanidazole, formed after labeling Flortanidazole with 18F, is a hypoxic PET imaging tracer and prognostic imaging biomarker. Flortanidazole can be used in the study of non-small cell lung cancer and colorectal cancer .
Cat. No.: HY-182944
CAS No.: 1265900-99-9
Target:
Research Areas:
GATT-44 is a blood-brain barrier-permeable, selective GABA transporter 1 (GAT-1) ligand with an IC50 of 126 nM. GATT-44 shows selectivity for GAT-2, GAT-3 and BGT-1 subtypes, and undergoes copper-mediated 18F-radiofluorination. The radiolabeled GATT-44 ([ 18F]GATT-44) exhibits brain uptake, metabolic stability and high GAT-1 binding specificity in non-human primates. GATT-44 is applicable for research on neurodegenerative and neuropsychiatric diseases .
Cat. No.: HY-181083
CAS No.: 3046416-94-5
Target:
Research Areas:
Tau ligand-2 is a tau aggregate ligand with a Ki value of 0.99 nM. Radiolabeled ( 18F) Tau ligand-2 serves as a PET tracer. Tau ligand-2 is applicable to research related to Alzheimer's disease .
Cat. No.: HY-W724743
CAS No.: 727718-93-6
Target:
Research Areas:
Losartan azide is a click chemistry reagent containing an azide group and is a synthetic intermediate for the preparation of angiotensin AT1R-targeted renal PET imaging probe [18 F]fluoropyridine-losartan .
Cat. No.: HY-181351
Target:
Research Areas:
PSN09 is a blood-brain barrier-permeable agonist of PSAM 4-GlyR and PSAM 4-5-HT3 receptors with high affinity. 18F-labeled PSN09 serves as a radiotracer for PET imaging in non-human primates .
Cat. No.: HY-176895
CAS No.: 2377146-66-0
Target:
Research Areas:
L-Dopa precursor-1 (Compound 5a) is the precursor of 18F-L-Dopa. L-Dopa precursor-1 serves as a core basis for radioactive labeling precursors, allowing the introduction of non-metallic radioactive elements through radiolabeling reactions. L-Dopa precursor-1 can be used for the study of RDN surgery for refractory hypertension, chronic kidney disease .
Cat. No.: HY-P11888
CAS No.: 1886065-39-9
Target:
Research Areas:
Cat. No.: HY-181853
Research Areas:
NOTA-SP₂A-PSMAL is a ligand targeting prostate-specific membrane antigen (PSMA), which competitively binds to PSMA with high binding affinity and an IC50 value of 0.26 nM. 18F-labeled NOTA-SP2A-PSMAL can be used as a PET tracer for positron emission tomography imaging of prostate cancer. NOTA-SP2A-PSMAL can be used for the synthesis and research of radionuclide conjugates (RDCs) .
Cat. No.: HY-180832
Target:
Research Areas:
COX-1 ligand 1 (Compound 44) is a selective COX-1 ligand (Kds or Kis: 22 nM for rhesus monkey COX-1; 43 nM for hCOX-1). COX-1 ligand 1 inhibits [ 3H]PS13 binding to human COX-1. COX-1 ligand 1, when radiolabeled with 11C or 18F, can be used in studies of COX-1 imaging and psychiatric disorders .
Cat. No.: HY-182746
Target:
Research Areas:
RG7388-PEG3-Click-F is a fluorinated analog of the MDM2 inhibitor RG7388 (HY-15676), with an IC50 of 16.8 nM against MDM2. [ 18F]RG7388-PEG3-Click-F exhibits high uptake and specificity in MDM2-expressing myeloma cells, and can be used for non-invasive assessment of MDM2 protein expression levels in tumors .
Cat. No.: HY-D3174
CAS No.: 2688758-23-6
Cat. No.: HY-181816
CAS No.: 3095344-37-6
Target:
Research Areas:
PD-1/PD-L1-IN-60 is the counterpart of the small-molecule immuno-probe [ 18F] LG‑8, and the two together enable integrated immuno-diagnosis and therapy. PD-1/PD-L1-IN-60 exhibits potent anti-tumor activity in mouse models of melanoma and lung cancer with high PD‑L1 uptake. PD-1/PD-L1-IN-60 can be used for relevant research on melanoma and lung cancer .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
