COX-1 ligand 1
COX-1 ligand 1 (Compound 44) is a selective COX-1 ligand (Kds or Kis: 22 nM for rhesus monkey COX-1; 43 nM for hCOX-1). COX-1 ligand 1 inhibits [3H]PS13 binding to human COX-1. COX-1 ligand 1, when radiolabeled with 11C or 18F, can be used in studies of COX-1 imaging and psychiatric disorders.
For research use only. We do not sell to patients.
- Formula: C17H15F2N3O2
- Molecular Weight:331.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Kds or Kis: 22 nM for rhesus monkey COX-1; 43 nM for hCOX-1[1]
Chemical Information
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Molecular Weight 331.32
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Formula C17H15F2N3O2
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SMILES
COC1=CC=C(C2=NC(OCCF)=NN2C3=CC=C(F)C=C3)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)