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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
105 Results for "
absorption enhancer
" in MedChemExpress (MCE) Product Catalog:
Products (105)
105 Results for "absorption enhancer" in MCE Product Catalog:
Cat. No.: HY-177840
Target:
Research Areas:
Liposomal Curcumin is a specialized delivery system that encapsulates Curcumin (HY-N0005) within tiny liposomes. These liposomes act as protective shells, enhancing the absorption and bioavailability of Curcumin. Curcumin (Diferuloylmethane), a natural phenolic compound, is a p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription. Curcumin is a photosensitizer against microorganisms. Curcumin shows inhibitory effects on NF-κB and MAPKs, and has diverse pharmacologic effects including anti-inflammatory, antioxidant, antiproliferative and antiangiogenic activities. Curcumin induces stabilization of Nrf2 protein through Keap1 cysteine modification.
The product size below only indicate the effective content of Curcumin.
The product size below only indicate the effective content of Curcumin.
Cat. No.: HY-113024R
CAS No.: 1189-37-3
Cat. No.: HY-N0378BGL
CAS No.: 69-65-8
Synonyms: Mannitol, M100 (GMP Like); Mannite, M100 (GMP Like)
Cat. No.: HY-N0378S
Synonyms: Mannitol-d8; Mannite-d8
Cat. No.: HY-N0378S5
CAS No.: 75607-68-0
Synonyms: Mannitol-d1; Mannite-d1
Cat. No.: HY-N0378S3
CAS No.: 287100-69-0
Synonyms: Mannitol-2-13C; Mannite-2-13C
Cat. No.: HY-N19827
CAS No.: 84607-60-3
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Cat. No.: HY-W074886
CAS No.: 52558-73-3
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N-Methyl-N-tetradecanoylglycine is a rectal absorption promoter. N-Methyl-N-tetradecanoylglycine enhances rectal absorption of antibiotics .
Cat. No.: HY-156957
CAS No.: 300718-75-6
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5-CNAC disodium is an orally active enhancer of absorption, with no pharmacological activity on its own. 5-CNAC disodium can significantly enhance the absorption efficiency of the drug (such as Salmon calcitonin (HY-P0090)) when administered together with it in the gastrointestinal tract. 5-CNAC disodium binds reversibly and non-covalently to peptide drugs, protecting them from degradation by gastrointestinal enzymes, increasing their lipid solubility, promoting passive transcellular absorption, and not damaging the integrity of the intestinal epithelium. 5-CNAC disodium can be used in the research of adjuvants for orally administered peptide agents .
Cat. No.: HY-177838
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Liposomal Silymarin is a specialized delivery system that encapsulates silymarin within tiny liposomes. These liposomes act as protective shells, enhancing the absorption and bioavailability of silymarin. Silymarin is a natural flavonoid compound derived
Cat. No.: HY-Y1422T
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Lipase, Porcine is an orally active triglyceride hydrolase and fat absorption enhancer. Lipase, Porcine catalyzes the breakdown of triglycerides into fatty acids, as well as the hydrolysis of triglycerides and other carboxylic acid esters. Lipase, Porcine increases the absorption coefficients of fats, proteins and carbohydrates. Lipase, Porcine can be used in studies related to exocrine pancreatic insufficiency and congenital pancreatic triglyceride lipase deficiency .
Cat. No.: HY-D3235
CAS No.: 2540586-21-6
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Cinnamohydrazide, an unsaturated carboxylic acid derivative, serves as a precursor to aspartame through enzyme-mediated amination to phenylalanine. This compound may offer potential benefits in the prevention and treatment of diabetes by facilitating insulin secretion, enhancing pancreatic β-cell function, inhibiting hepatic gluconeogenesis, promoting glucose uptake, amplifying insulin signaling pathways, delaying carbohydrate digestion and glucose absorption, and reducing protein glycation and insulin fibrillation.
Cat. No.: HY-188004
Decitabine-Cisplatin Liposome is a delivery system that encapsulates Decitabine (HY-A0004) and Cisplatin (HY-17394) within tiny liposomes. The liposomes act as a protective layer, enhancing the absorption and bioavailability of both Decitabine and Cisplatin. The combination of Decitabine and Cisplatin synergistically induces Sox2 DNA demethylation and promotes Sox2 gene expression, making it a useful tool for gastric cancer research .
Cat. No.: HY-W248590
CAS No.: 199444-11-6
Synonyms: IR-775 chloride
Research Areas:
IR-775 chloride is a cyanine dye with near-infrared absorption (Ex/Em = 775/795 nm). IR-775 chloride acts as a photosensitizer or photothermal agent, and induces apoptosis via generating ROS or exerting photothermal effects upon irradiation; its combination with 2-methoxyestradiol (HY-12033) inhibits SOD2 to enhance photodynamic therapy (PDT) efficacy, and its liposomal encapsulation enables phytotherapy-photothermal therapy (PTT) synergy. IR-775 chloride is applicable for investigating PDT/PTT and near-infrared fluorescence imaging in ovarian cancer and breast cancer .
Cat. No.: HY-187082
CAS No.: 587879-32-1
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P552-02 is an epithelial sodium channel (ENaC) inhibitor. P552-02 blocks ENaC function in humans, guinea pigs, rats and sheep, exhibits the characteristic of reduced dissociation rate after binding to ENaC, inhibits ENaC-mediated short-circuit current, and slows the absorption of airway surface liquid (ASL). P552-02 induces hyperkalemia in guinea pigs and rats, blocks the activity of airway ENaC in guinea pigs, and enhances mucociliary clearance in sheep both in vivo and in vitro. P552-02 is applicable to cystic fibrosis-related research .
Cat. No.: HY-W251144
CAS No.: 76372-75-3
Synonyms: PTCDI-C5
Target:
N,N′-Dipentyl-3,4,9,10-perylenedicarboximide (PTCDI-C5) is an organic semiconductor compound with excellent electron transport activity. N,N′-Dipentyl-3,4,9,10-perylenedicarboximide exhibits high performance in organic field effect transistors (OFETs) and can effectively improve the carrier mobility of the device. The application of N,N′-Dipentyl-3,4,9,10-perylenedicarboximide in organic photovoltaic (OPV) materials enhances the light absorption performance, thereby improving the photoelectric conversion efficiency. N,N′-Dipentyl-3,4,9,10-perylenedicarboximide has also been widely studied for the development of high-performance sensors and fluorescent materials.
Cat. No.: HY-182014
CAS No.: 2408041-54-1
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TLC-2716 is an orally available, gut- and liver-restricted inhibitor against LXRα and LXRβ, with EC50 values of 7 nM and 15 nM, respectively. TLC-2716 represses LXRα/β transcriptional activity, downregulates genes involved in lipogenesis, lipid absorption and lipoprotein metabolism, and preserves peripheral reverse cholesterol transport. TLC-2716 reduces lipid accumulation, suppresses inflammation and fibrotic gene expression, enhances triglyceride-rich lipoprotein clearance, and improves glucose homeostasis and insulin sensitivity. TLC-2716 lowers serum and hepatic triglycerides, plasma cholesterol and other atherogenic lipid profiles in experimental models and humanized liver mice. TLC-2716 can be used for the research of dyslipidemia and related cardiometabolic disorders .
Cat. No.: HY-178413S
Synonyms: Mannitol-d4; Mannite-d4
Cat. No.: HY-D3119
CAS No.: 2246946-49-4
Research Areas:
MitoAIE1 is a Fluorescent probe for mitochondrial viscosity detection. MitoAIE1 contains a pyridinium structural unit, which endows it with mitochondria-targeting specificity. The detection mechanism of this probe is based on aggregation-induced emission (AIE): in low-viscosity media such as PBS buffer, intramolecular rotation leads to non-radiative energy dissipation, resulting in only weak fluorescence; however, in high-viscosity environments such as the mitochondrial matrix or the vicinity of the inner mitochondrial membrane, such intramolecular motion is restricted, thereby significantly enhancing its fluorescent signal; in addition, this probe is not interfered by changes in microenvironment polarity and pH. Its emission wavelength is 625 nm, with absorption peaks at 325 nm and 450 nm; when transferred from low-viscosity PBS to high-viscosity 99% glycerol, its fluorescence intensity at 625 nm can be increased by 38-fold. It can be used to monitor changes in mitochondrial viscosity during processes such as Stauroporine (HY-15141)-induced apoptosis and starvation-induced mitophagy in live cells, and has good biocompatibility .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
