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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
120 Results for "
5-hydroxytryptamine
" in MedChemExpress (MCE) Product Catalog:
Products (120)
120 Results for "5-hydroxytryptamine" in MCE Product Catalog:
Cat. No.: HY-103116
CAS No.: 133364-62-2
Target:
Research Areas:
DV-7028 is a selective 5-hydroxytryptamine2 (5-HT2) receptor antagonist .
Cat. No.: HY-103090
CAS No.: 299433-10-6
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NPS ALX Compound 4a is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist, with an IC50 of 7.2 nM and a Ki of 0.2 nM .
Cat. No.: HY-103090A
CAS No.: 1781934-44-8
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NPS ALX Compound 4a dihydrochloride is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist, with an IC50 of 7.2 nM and a Ki of 0.2 nM .
Cat. No.: HY-14334
CAS No.: 744218-85-7
Synonyms: WAY-255315
Target:
Research Areas:
SAM-315 (WAY-255315) is a potent antagonist of 5-Hydroxytryptamine-6, with Ki and IC50 of 1.1 nM and 4.6 nM, respectively. SAM-315 significantly increases acetylcholine and glutamate release in hippocampus of the brain .
Cat. No.: HY-P703149
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HTR2A; Serotonin Receptor 2A; Prev. HTR2; Serotonin 5-HT-2A Receptor; 5-HT2A; 5-HT2 Receptor; 5-hydroxytryptamine (Serotonin) Receptor 2A, G Protein-Coupled; 5-HT-2A; 5-hydroxytryptamine (Serotonin) Receptor 2A; 5-hydroxytryptamine Receptor 2A; 5-HT-2
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P703150
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HTR2A; Serotonin Receptor 2A; Prev. HTR2; Serotonin 5-HT-2A Receptor; 5-HT2A; 5-HT2 Receptor; 5-hydroxytryptamine (Serotonin) Receptor 2A, G Protein-Coupled; 5-HT-2A; 5-hydroxytryptamine (Serotonin) Receptor 2A; 5-hydroxytryptamine Receptor 2A; 5-HT-2
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P810892
Synonyms: HTR2; 5-hydroxytryptamine receptor 2A; 5-HT-2; 5-HT-2A; Serotonin receptor 2A
Cat. No.: HY-129444
CAS No.: 73423-36-6
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MD 780236 free base is a substrate and selective inhibitor of monoamine oxidase B (MAO-B), competitive with phenylethylamine and 5-hydroxytryptamine (5-HT) .
Cat. No.: HY-123028A
Synonyms: Arginylphenylalaninamide TFA
Rfamide TFA (Arginylphenylalaninamide TFA) is a neuropeptide that has contraction-inducing activity in gastropod muscles. Its contractile effect is additive with acetylcholine and is regulated by 5-hydroxytryptamine. It can also mobilize intracellular calcium to maintain tension .
Cat. No.: HY-FLA0019A
CAS No.: 199739-10-1
Synonyms: 9-Hydroxyrisperidone palmitate solution
Target:
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Paliperidone palmitate solution is mainly composed of Paliperidone palmitate (HY-A0019A). Paliperidone palmitate is an orally effective competitive antagonist of dopamine D2 receptors and 5-hydroxytryptamine 2A (5-HT2A) receptors that can cross the blood-brain barrier. Paliperidone palmitate competitively inhibits the effects of dopamine and 5-hydroxytryptamine by binding to dopamine D2 receptors and 5-HT2A receptors, regulating the balance of the neurotransmitter system and thus exerting antipsychotic activity. Paliperidone palmitate is mainly used in the research field of schizophrenia .
Cat. No.: HY-E72108
Human UGT1A6 is a UDP-glucuronosyltransferase. UGT1A6 catalyzes the glucuronidation of 5-hydroxytryptamine (HY-B1473A), 1-Naphthol (HY-Y1309), and Acetaminophen (HY-66005). Human UGT1A6 can be used in studies related to the pathogenesis of bladder cancer .
Cat. No.: HY-B0884AR
CAS No.: 25953-17-7
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Minaprine dihydrochloride (Standard) is the analytical standard of Minaprine dihydrochloride (HY-B0884A). This product is intended for research and analytical applications. Minaprine dihydrochloride is a brain-penetrant monoamine oxidase inhibitor. Minaprine dihydrochloride also weakly inhibits acetylcholinesterase (AChE) activity. Minaprine dihydrochloride reduces intraneuronal dopamine metabolism, lowers striatal homovanillic acid and dihydroxyphenylacetic acid levels, and raises striatal 3-methoxytyramine and 5-hydroxytryptamine levels. Minaprine dihydrochloride exhibits convulsant, antidepressant properties .
Cat. No.: HY-19046A
CAS No.: 53873-21-5
Synonyms: SC 48274; BTG 1501
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Research Areas:
AGN‑2979 (SC 48274; BTG 1501) is an orally active and selective tryptophan hydroxylase inhibitor with antidepressant-like and anxiolytic-like activities. AGN‑2979 inhibits stress-induced activation of tryptophan hydroxylase, thereby limiting the biosynthesis of 5-hydroxytryptamine in the brain. AGN-2979 possesses non-sedative anxiolytic and cognitive-enhancing properties. AGN-2979 is applicable to research related to depression and generalized anxiety disorder .
Cat. No.: HY-118854
CAS No.: 36981-91-6
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Fepradinol is an orally active nonsteroidal anti-inflammatory agent. Fepradinol inhibits the increase in vascular permeability induced by histamine, 5-hydroxytryptamine, and bradykinin, reduces exudate volume, prevents leukocyte migration, and suppresses acute inflammation models. Fepradinol also induces thrombotic vasculopathy with epidermal necrosis, without leukocytoclastic vasculitis; triggers occlusive contact dermatitis presenting as purpuric papulonecrotic lesions, and causes strongly positive patch test reactions. Fepradinol can be used in research related to occlusive contact dermatitis and acute inflammation .
Cat. No.: HY-118854B
CAS No.: 67704-50-1
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Research Areas:
Fepradinol hydrochloride is an orally active nonsteroidal anti-inflammatory agent. Fepradinol hydrochloride inhibits the increase in vascular permeability induced by histamine, 5-hydroxytryptamine, and bradykinin, reduces exudate volume, prevents leukocyte migration, and suppresses acute inflammation models. Fepradinol hydrochloride also induces thrombotic vasculopathy with epidermal necrosis, without leukocytoclastic vasculitis; triggers occlusive contact dermatitis presenting as purpuric papulonecrotic lesions, and causes strongly positive patch test reactions. Fepradinol hydrochloride can be used in research related to occlusive contact dermatitis and acute inflammation .
Cat. No.: HY-118854A
CAS No.: 1185076-47-4
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Research Areas:
Fepradinol oxalate is an orally active nonsteroidal anti-inflammatory agent. Fepradinol oxalate inhibits the increase in vascular permeability induced by histamine, 5-hydroxytryptamine, and bradykinin, reduces exudate volume, prevents leukocyte migration, and suppresses acute inflammation models. Fepradinol oxalate also induces thrombotic vasculopathy with epidermal necrosis, without leukocytoclastic vasculitis; triggers occlusive contact dermatitis presenting as purpuric papulonecrotic lesions, and causes strongly positive patch test reactions. Fepradinol oxalate can be used in research related to occlusive contact dermatitis and acute inflammation .
Cat. No.: HY-W367959
CAS No.: 50366-32-0
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Research Areas:
Flunamine is a broad-spectrum monoamine transporter inhibitor that inhibits the uptake of dopamine (DA), 5-hydroxytryptamine (5-HT), and noradrenaline (NA) in rat brain synaptosomes. The IC50 values of Flunamine for DA and 5-HT uptake in rat striatal synaptosomes are 0.26 μM and 0.17 μM, respectively, and the IC50 values for 5-HT and NA uptake in hypothalamic synaptosomes are 0.24 μM and 0.092 μM, respectively. Flunamine acts through broad-spectrum inhibition of dopaminergic, serotonergic, and noradrenergic monoamine reuptake and is used in research related to depression and Parkinson's disease .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
