1101 Results for "

Anticancer agent

" in MedChemExpress (MCE) Product Catalog:
Products (1101)

1101 Results for "Anticancer agent" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-109523
CAS No.: 143201-11-0
Purity:  99.84%
Cerivastatin sodium is a synthetic lipid-lowering agent and a highly potent, well-tolerated and orally active HMG-CoA reductase inhibitor, with a Ki of 1.3 nM/L. Cerivastatin sodium reduces low-density lipoprotein cholesterol levels. Cerivastatin sodium also inhibits proliferation and invasiveness of MDA-MB-231 cells, mainly by RhoA inhibition, and has anti-cancer effect .
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2 Cited Publications
Cat. No.: HY-B0900
CAS No.: 104-46-1
Synonyms: Anise camphor; p-Propenylanisole; Isoestragole
Anethole is a type of orally active aromatic compound that is widely found in nature and used as a flavoring agent. Anethole possesses anticancer, anti-inflammatory, antioxidant, antibacterial, antifungal, anesthetic, estrogenic, central nervous system depressant, hypnotic, insecticidal, and gastroprotective effects. Anethole can be used in the study of oxidative stress-related skin diseases and prostate cancer .
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2 Cited Publications
Cat. No.: HY-121410
CAS No.: 55134-13-9
Purity:  ≥88.0%
Research Areas:  

Infection Cancer

Narasin is a cationic ionophore antibiotic and coccidiostat agent. Narasin inhibits NF-κB signaling and induces tumor cells apoptosis. Narasin has antimicrobial, antiviral anticancer activity. Narasin inhibits tumor metastasis and growth of ERα‑positive breast cancer cells by inactivation of the TGF-β/SMAD3 and IL‑6/STAT3 signaling pathways .
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2
2 Cited Publications
Cat. No.: HY-N0248
CAS No.: 58316-41-9
Saikosaponin B2 is an antiviral and anticancer agent that regulates multiple transporters (such as various solute carriers and ATP-binding cassette transporters including MRP1, MRP2, and OCT2). Saikosaponin B2 is isolated from the plant glycoside component of the roots of Bupleurum scorzonerifolium. Saikosaponin B2 enhances the liver targeting of anticancer drugs via vinegar-baked Radix Bupleuri. Saikosaponin B2 inhibits HCV entry, replication, and translation, is effective against Daclatasvir (HY-10466)-resistant strains, and exerts a synergistic effect when used in combination with Daclatasvir. Saikosaponin B2 is commonly used in studies related to hepatocellular carcinoma and HCV infection .
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2
2 Cited Publications
Cat. No.: HY-135318
CAS No.: 787634-60-0
Purity:  98.56%
Research Areas:  

Cancer

NBDHEX is a potent glutathione S-transferase P1-1 (GSTP1-1) inhibitor. NBDHEX induces apoptosis of tumor cells. NBDHEX acts as an anticancer agent by inhibiting GSTs catalytic activity, avoiding inconvenience of the inhibitor extrusion from the cell by specific pumps and disrupting the interaction between the GSTP1-1 and key signaling effectors. NBDHEX can also act as late-phase autophagy inhibitor .
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2 Cited Publications
Cat. No.: HY-P1682
CAS No.: 1051366-32-5
Synonyms: POL6326
Target:  

CXCR Arrestin

Research Areas:  

Cancer

Balixafortide (POL6326) is a potent, selective, well-tolerated peptidic CXCR4 antagonist with an IC50 < 10 nM. Balixafortide shows 1000-fold selective for CXCR4 than a large panel of receptors including CXCR7. Balixafortide blocks β-arrestin recruitment and calcium flux with IC50s < 10 nM. Balixafortide is also a potent hematopoietic stem and progenitor cell (HSPC) mobilizing agent. Anti-cancer effects .
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2 Cited Publications
Cat. No.: HY-B0166R
CAS No.: 50-81-7
Synonyms: L-Ascorbate (Standard); Vitamin C (Standard)
L-Ascorbic acid (Standard) is the analytical standard of L-Ascorbic acid. This product is intended for research and analytical applications. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor . L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .
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2 Cited Publications
Cat. No.: HY-B0914
CAS No.: 112-38-9
Synonyms: Undecylenic acid
10-Undecenoic acid (Undecylenic acid) is an antifungal agent. 10-Undecenoic acid inhibits Aβ oligomerization, scavenges ROS and inhibits μ-calpain activity. 10-Undecenoic acid has neuroprotective effects. 10-Undecenoic acid has anticancer effects on a variety of tumors. 10-Undecenoic acid inhibits C. albicans biofilm formation and MRSA infection. 10-Undecenoic acid inhibits quorum sensing signals of Bacillus subtilis and Pseudomonas aeruginosa .
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2 Cited Publications
Cat. No.: HY-P1682A
Synonyms: POL6326 TFA
Target:  

CXCR Arrestin

Research Areas:  

Cancer

Balixafortide TFA (POL6326 TFA) is a potent, selective, well-tolerated peptidic CXCR4 antagonist with an IC50 < 10 nM. Balixafortide TFA shows 1000-fold selective for CXCR4 than a large panel of receptors including CXCR7. Balixafortide TFA blocks β-arrestin recruitment and calcium flux with IC50s < 10 nM. Balixafortide TFA is also a potent hematopoietic stem and progenitor cell (HSPC) mobilizing agent. Anti-cancer effects .
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2 Cited Publications
Cat. No.: HY-B0914A
CAS No.: 557-08-4
Synonyms: Zinc undecylenate
10-Undecenoic acid zinc salt (Undecylenic acid zinc salt) is an antifungal agent. 10-Undecenoic acid zinc salt inhibits Aβ oligomerization, scavenges ROS and inhibits μ-calpain activity. 10-Undecenoic acid zinc salt has neuroprotective effects. 10-Undecenoic acid zinc salt has anticancer effects on a variety of tumors. 10-Undecenoic acid zinc salt inhibits C. albicans biofilm formation and MRSA infection. 10-Undecenoic acid zinc salt inhibits quorum sensing signals of Bacillus subtilis and Pseudomonas aeruginosa .
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2
2 Cited Publications
Cat. No.: HY-10996A
CAS No.: 1784282-12-7
Purity:  99.65%
KHS101 is a blood-brain barrier-penetrant anticancer agent that primarily functions by inhibiting HSPD1 (IC50 = 14.4 μM) and TACC3 across different cellular backgrounds. KHS101 promotes the aggregation of HSPD1 with client proteins, destabilizes TACC3, and reduces the levels of TACC3, Aurora A and PLK1. KHS101 induces autophagy, apoptosis, cell cycle exit and neuronal differentiation; it suppresses cancer cell growth, motility, EMT and stemness; it also impairs mitochondrial bioenergetics and glycolysis in glioblastoma cells. KHS101 can be used in research related to glioblastoma multiforme and breast cancer .
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2
2 Cited Publications
Cat. No.: HY-153713
Purity:  98.05%
Target:  

RIBOTAC c-Myc Apoptosis

Research Areas:  

Cancer

MYC-RIBOTAC is a nucleic acid-targeting degrader (ribonuclease-targeting chimera, RIBOTAC) that targets the MYC internal ribosome entry site (IRES). MYC-RIBOTAC contains a MYC mRNA binding component and a small molecule that recruits and locally activates RNAse L1. MYC-RIBOTAC reduces MYC mRNA and protein expression levels, induces cell apoptosis, and can be used for antitumor research . MYC-RIBOTAC consists of pre-miR-155 binder Anticancer agent 167 (HY-156839), RNA binder NCI-B16 (HY-156215), and Linker Amino-PEG4-alcohol (HY-W008005).
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1
1 Cited Publications
Cat. No.: HY-147918
CAS No.: 124811-87-6
Purity:  99.92%
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

Anticancer agent 73 (compound CIB-3b) is a anticancer agent, potently targeting TAR RNA-binding protein 2 (TRBP) and disrupts its interaction with Dicer. Anticancer agent 73 can rebalance the expression profile of oncogenic or tumor-suppressive miRNAs. Anticancer agent 73 suppresses the proliferation and metastasis of HCC in vitro and in vivo .
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1
1 Cited Publications
Cat. No.: HY-B2102
CAS No.: 125-13-3
Synonyms: Oxyphenisatin
Target:  

Drug Derivative

Research Areas:  

Cancer

Oxyphenisatine (Oxyphenisatin) is a laxative. Oxyphenisatin acetate is the pro-agent of oxyphenisatin with anticancer activity.
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1
1 Cited Publications
Cat. No.: HY-13741
CAS No.: 221635-42-3
Purity:  97.10%
Synonyms: NSC 697726
Target:  

Apoptosis

Research Areas:  

Cancer

RH1 (NSC 697726) is a potent bioreductive agent with profound anti-cancer activity in vitro and in vivo.
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1
1 Cited Publications
Cat. No.: HY-12352A
CAS No.: 2415263-08-8
Purity:  98.68%
Target:  

STAT Apoptosis

Research Areas:  

Cancer

HJC0416 hydrochloride is a potent and orally active STAT3 inhibitor with an enhanced anticancer profile than Stattic (HY-13818). HJC0416 hydrochloride is a promising anti-cancer agent for breast cancer study .
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1
1 Cited Publications
Cat. No.: HY-106541
CAS No.: 130726-68-0
Purity:  99.58%
Target:  

Fungal

Research Areas:  

Infection Cancer

Neticonazole is an imidazole derivative and a potent and long-acting antifungal agent. Neticonazole has anti-infection and anti-cancer effects .
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1
1 Cited Publications
Cat. No.: HY-128365
CAS No.: 130773-02-3
Purity:  99.96%
Target:  

Fungal

Research Areas:  

Infection Cancer

Neticonazole hydrochloride is an imidazole derivative and a potent and long-acting antifungal agent. Neticonazole hydrochloride has anti-infection and anti-cancer effects .
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1
1 Cited Publications
Cat. No.: HY-N9438
CAS No.: 1891-29-8
Lactucin is an anti-inflammatory agent. Lactucin induces cancer cell apoptosis. Lactucin also shows analgesic, anticancer and antimalarial activities .
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1
1 Cited Publications
Cat. No.: HY-113064
CAS No.: 2897-21-4
Purity:  ≥99.0%
Selenocystine is a broad-spectrum anti-cancer agent. Selenocystine induces DNA damage in HepG2 cells, particularly in the form of DNA double strand breaks (DSBs). Selenocystine exhibits great promise as a therapeutic or adjuvant agent targeting DNA repair for cancer treatment .
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