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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1154 Results for "
SARS-CoV-2 M_long
" in MedChemExpress (MCE) Product Catalog:
Products (1154)
1154 Results for "SARS-CoV-2 M_long" in MCE Product Catalog:
Cat. No.: HY-N8671
CAS No.: 256520-90-8
Category:
Cat. No.: HY-P10975
CAS No.: 2484874-12-4
Target:
Research Areas:
Cat. No.: HY-P5642A
Synonyms: RC-101 TFA
Target:
HIV SARS-CoV Influenza Virus Flavivirus HSV Bacterial Fungal Toll-like Receptor (TLR) Ser/Thr Protease
Research Areas:
Cat. No.: HY-W699983
CAS No.: 74362-46-2
Synonyms: Glyoxaline-15N2; 1,3-Diaza-2,4-cyclopentadiene-15N2
Cat. No.: HY-161070
CAS No.: 877660-90-7
Research Areas:
Antiviral agent 46 (compound 4) is a derivative of cannabidiol (CBD) with anti-SARS-CoV-2 (IC50: 1.90 μM) and ACE2 activity (IC50: 1.37 μM) .
Cat. No.: HY-P702190
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Replicase polyprotein 1a; pp1a; ORF1a polyprotein; Host translation inhibitor nsp1; Leader protein, Non-structural protein 1 (nsp1); Non-structural protein 2 (nsp2); p65 homolog; Papain-like protease nsp3; EC:3.2.2.-; EC:3.4.19.12; EC:3.4.22.-; Non-struct
Species:
Virus
Source:
E. coli
Cat. No.: HY-P703532
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: Replicase polyprotein 1ab; pp1ab; ORF1ab polyprotein; Host translation inhibitor nsp1; Leader protein; Non-structural protein 1 (nsp1); Non-structural protein 2 (nsp2); p65 homolog; Papain-like protease nsp3 (EC:3.2.2.-, EC:3.4.19.12, EC:3.4.22.-); Non-
Species:
Virus
Source:
E. coli
Cat. No.: HY-P703533
Synonyms: Replicase polyprotein 1ab; pp1ab; ORF1ab polyprotein; Host translation inhibitor nsp1; Leader protein; Non-structural protein 1 (nsp1); Non-structural protein 2 (nsp2); p65 homolog; Papain-like protease nsp3 (EC:3.2.2.-, EC:3.4.19.12, EC:3.4.22.-); Non-
Species:
Virus
Source:
E. coli
Cat. No.: HY-N2016R
CAS No.: 50906-56-4
Category:
Terpenoids Sesquiterpenes Artemisia carvifolia Buch.-Ham. ex Roxb. Plants Compositae Extract
Target:
Cat. No.: HY-P990705
CAS No.: 2765086-18-6
Synonyms: REGN-15160
Target:
Research Areas:
Cat. No.: HY-P990725
Target:
Research Areas:
Cat. No.: HY-P990768
CAS No.: 2857862-27-0
Target:
Research Areas:
Cat. No.: HY-P991170
CAS No.: 3031270-42-2
Cat. No.: HY-12502B
CAS No.: 111011-53-1
Synonyms: NZ-105 hydrochloride; (±)-Efonidipine hydrochloride
Target:
Research Areas:
Efonidipine (NZ-105) hydrochloride is an orally active dual L-type and T-type calcium channel blocker (CCB) with IC50 values of 1.8 and 350 nM, respectively. Efonidipine hydrochloride inhibits SARS-CoV-2 main protease. Efonidipine hydrochloride modulates adrenal steroidogenesis by increasing the expression of steroidogenic acute regulatory protein (StAR), dbcAMP-or angiotensin II-induced StAR mRNA expression and DHEA-S production, while suppressing the biosynthesis of aldosterone and cortisol. Efonidipine hydrochloride reduces plasma aldosterone levels in vivo. Efonidipine hydrochloride improves cardiac function in heart failure models by inhibiting T-type calcium channels (via both tonic and use-dependent blockade), independently of blood pressure reduction. Efonidipine hydrochloride can be used for research in hypertension, heart failure, and disorders involving dysregulated steroid hormone synthesis [2] .
Cat. No.: HY-145973B
Research Areas:
3'OMe-m7GpppAmpG (Tris) is a trinucleotide Cap1 analog with the structure m7 (3'OMeG)(5') ppp (5')(2'OMeA) pG, and also functions as a cis-acting ligase ribozyme inhibitor. 3'OMe-m7GpppAmpG (Tris) effectively reduces free 5'-triphosphate groups on RNA transcripts, thereby enabling efficient co-transcriptional capping of in vitro transcribed mRNA. 3'OMe-m7GpppAmpG (Tris) is not only widely used in the preparation of modified mRNA including trivalent influenza vaccine candidates, but also applicable to studies related to SARS-CoV-2 infection and other relevant research [2] .
Cat. No.: HY-N9921
CAS No.: 163597-24-8
Category:
Cat. No.: HY-P990711
Target:
Research Areas:
Cat. No.: HY-P990756
CAS No.: 2858673-18-2
Target:
Research Areas:
Cat. No.: HY-P990950
CAS No.: 2937321-40-7
Synonyms: SA-55
Target:
Research Areas:
Research Areas:
AM-001 is a selective Epac1 inhibitor with an IC50 value of 47.8-53.7 μM. AM-001 blocks cAMP (Cyclic AMP) (HY-B1511)-induced conformational changes of Epac1, inhibits Epac1-dependent activation of Rap1, and does not compete with cAMP for binding to Epac1. AM-001 disrupts the formation of the Epac1-GRK5 complex, blocks nuclear import of GRK5, and inhibits GRK5-mediated nuclear export of HDAC5 and activation of MEF2. AM-001 can be used in research related to heart disease, myocardial ischemia/reperfusion injury, SARS-CoV-2 infection, influenza A virus infection, atrial fibrillation and idiopathic pulmonary fibrosis [2] .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
