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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
138 Results for "
crosslinking agent
" in MedChemExpress (MCE) Product Catalog:
Products (138)
138 Results for "crosslinking agent" in MCE Product Catalog:
Cat. No.: HY-185389
Synonyms: Liposomal cisplatin
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Cisplatin liposome is a liposome-encapsulated form of Cisplatin (HY-17394). Cisplatin (CDDP) is an anti-tumor chemotherapeutic agent that cross-links with DNA, causing DNA damage in cancer cells. Cisplatin liposome prolongs drug circulation time and slowly releases the drug, allowing it to accumulate in the tumor and exert its killing effect.
Cat. No.: HY-W414754
CAS No.: 438470-19-0
Cat. No.: HY-W110540J
CAS No.: 25852-47-5
Cat. No.: HY-W110540K
CAS No.: 25852-47-5
Cat. No.: HY-W110540L
CAS No.: 25852-47-5
Cat. No.: HY-W800818
CAS No.: 2230212-02-7
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(Z)-Non-2-enyl 6-bromohexanoate is an analogue of Biotin and a protein cross-linking agent.(Z)-Non-2-enyl 6-bromohexanoate binds less tightly to biotin-binding proteins such as Avidin and is easily displaced by Biotin. It is used in the preparation of agarose matrices for affinity-based isolation of streptavidin-fluorophore conjugates.
Cat. No.: HY-14572
CAS No.: 680199-06-8
Synonyms: SN 27858
Research Areas:
PR-104A (SN 27858) is the alcohol metabolite of phosphate proagent PR-104. PR-104A is a hypoxia-selective DNA cross-linking agent/DNA-damaging agent and cytotoxin. Antitumor Activity . PR-104A is metabolized under hypoxia by the 1-electron NADPH:cytochrome P450 oxidoreductase. PR-104A can be used for the research of relapsed/refractory T-lineage acute lymphoblastic leukemia (T-ALL) .
Cat. No.: HY-W010342R
CAS No.: 329-89-5
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6-Aminonicotinamide, a potent antimetabolite of nicotinamide, is competitive NADP+-dependent enzyme glucose-6-phosphate dehydrogenase (G6PD) inhibitor (Ki=0.46 μM). 6-Aminonicotinamide resultis ATP depletion and synergizes with DNA-crosslinking chemotherapy agents, such as Cisplatin (HY-17394), in killing cancer cells .
Cat. No.: HY-W781133
CAS No.: 106343-54-8
Synonyms: cis-[Pt(NH3)2N1-pyridineCl]Cl
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cDPCP (cis-[Pt(NH3)2(N1-pyridine)Cl]Cl) is a DNA crosslinking agent and also a substrate for OCT1 and OCT2. DPCP exhibits anticancer activity and can improve the survival rate of sarcoma-180 mice. cDPCP is suitable for the research of colorectal cancer and cancers with appropriate cation transporters .
Cat. No.: HY-23497
CAS No.: 24979-70-2
Poly(4-vinylphenol) is a polymer cross-linking agent that can be used to prepare non-toxic films. Poly(4-vinylphenol) is a sensitizer of titania for visible light photocatalysis. Poly(4-vinylphenol) also can be used as a water resistive wood adhesive, as a gate dielectric insulator in organic field effect transistors, and as a responsive surface coating .
Synonyms: CB 1954
Research Areas:
Tretazicar (CB 1954), an antitumor proagent, is highly selective against the Walker 256 rat tumour line. Tretazicar is enzymatically activated to generate a bifunctional agent, which can form DNA-DNA interstrand cross-links. Tretazicar in rat cells involves the reduction of its 4-nitro group to a 4-hydroxylamine by the enzyme NAD(P)H:quinone oxidoreductase 1 (NQO1) .
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PBD dimer-2 (compound 2c) is a C8-linked pyrrolobenzodiazepine dimer. PBD dimer-2 can span an extra base pair and cross-link the 5′-Pu-GA(T/A)TC-Py sequence. PBD dimer-2 can be used as a payload for antibody–agent conjugates (ADCs), and it can be used for the research of cancer .
Cat. No.: HY-W451406A
CAS No.: 956496-54-1
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NH2-PEG5000-NH2 is a PEG (MW = 5000) derivative with NH2 groups at both ends. NH2-PEG-NH2 can be used as a crosslinking agent in bioconjugation, hydrogel preparation, and nanotechnology, and can form stable amide bonds with active carboxyl groups or NHS ester groups .
Cat. No.: HY-W451406B
CAS No.: 956496-54-1
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NH2-PEG1000-NH2 is a PEG (MW = 1000) derivative with NH2 groups at both ends. NH2-PEG-NH2 can be used as a crosslinking agent in bioconjugation, hydrogel preparation, and nanotechnology, and can form stable amide bonds with active carboxyl groups or NHS ester groups .
Cat. No.: HY-W451406C
CAS No.: 956496-54-1
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NH2-PEG2000-NH2 is a PEG (MW = 2000) derivative with NH2 groups at both ends. NH2-PEG-NH2 can be used as a crosslinking agent in bioconjugation, hydrogel preparation, and nanotechnology, and can form stable amide bonds with active carboxyl groups or NHS ester groups .
Cat. No.: HY-W451406D
Target:
Research Areas:
NH2-PEG10000-NH2 is a PEG (MW = 10000) derivative with NH2 groups at both ends. NH2-PEG-NH2 can be used as a crosslinking agent in bioconjugation, hydrogel preparation, and nanotechnology, and can form stable amide bonds with active carboxyl groups or NHS ester groups .
Cat. No.: HY-W451406H
CAS No.: 956496-54-1
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NH2-PEG400-NH2 is a PEG (MW = 400) derivative with NH2 groups at both ends. NH2-PEG-NH2 can be used as a crosslinking agent in bioconjugation, hydrogel preparation, and nanotechnology, and can form stable amide bonds with active carboxyl groups or NHS ester groups .
Cat. No.: HY-106109
CAS No.: 114580-45-9
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FK 973 is a dihydrobenzoxazine anticancer agent. FK 973 selectively inhibits DNA synthesis and can form DNA cross-links through cytoplasmic activation. FK 973 exhibits significant antitumor activity in various animal tumor models and human tumor xenografts, with relatively weak myelosuppressive effects. FK 973 is sensitive to neural tumor cells. FK 973 can be used for DNA-targeted antitumor research .
Cat. No.: HY-W250309
CAS No.: 7575-23-7
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
