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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
409 Results for "
Reverse Transcriptase
" in MedChemExpress (MCE) Product Catalog:
Products (409)
409 Results for "Reverse Transcriptase" in MCE Product Catalog:
Cat. No.: HY-144112
CAS No.: 2761172-60-3
HIV-1 inhibitor-13 (compound 16c) is a orally active and potent HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI), with IC50 of 0.14 μM (HIV-1 RT). HIV-1 inhibitor-13 shows activity against a panel of HIV-1 resistant strains, with EC50 values of 2.85-18.0 nM .
Cat. No.: HY-W320523
CAS No.: 455303-00-1
Cat. No.: HY-121075R
CAS No.: 3952-78-1
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Alizarin complexone (Standard) is the analytical standard of Alizarin complexone (HY-121075). This product is intended for research and analytical applications. Alizarin complexone is a calcium-binding fluorescent dye. Alizarin complexone stains mineralized areas of bone by binding to calcium crystals. Alizarin complexone inhibits the reverse transcriptase activity of RAV-2, HIV-1, and RSV with IC50 values of 3.8 μg/mL, 45 μg/mL, and 100 μg/mL, respectively. Alizarin complexone exhibits antiviral activity against HIV-1 and RSV. Alizarin complexone delays RSV-induced tumor induction in chickens .
Cat. No.: HY-130050
CAS No.: 75580-37-9
Synonyms: BBM-928 A
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Cat. No.: HY-14920R
CAS No.: 134379-77-4
Synonyms: Reverset (Standard); d-d4FC (Standard)
Research Areas:
Dexelvucitabine (Standard) is the analytical standard of Dexelvucitabine. This product is intended for research and analytical applications. Dexelvucitabine (Reverset; d-d4FC), a Cytidine (HY-B0158) analog, is an orally active nucleoside reverse transcriptase inhibitor. Dexelvucitabine is a powerful agent against HIV-1-resistant viruses containing a thymidine analog and/or M184V mutation in the viral polymerase. Dexelvucitabine is a 2′-Deoxycytidine antiretroviral agent .
Cat. No.: HY-182497
CAS No.: 177577-59-2
U 95133 is a non-nucleoside reverse transcriptase inhibitor. U 95133 exhibits activity against both wild-type and mutant HIV-1 reverse transcriptase. U 95133 can be used in studies related to HIV infection .
Cat. No.: HY-120055
CAS No.: 343250-05-5
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CP-94707 is an HIV-1 reverse transcriptase (HIV-1 reverse transcriptase) inhibitor, with an IC50 of 4 μM against wild-type and HIV-1 reverse transcriptase Y181I-Y188L double mutant enzymes, and an IC50 of 10 μM against HIV-1 reverse transcriptase K103N mutant enzyme. CP-94707 inhibits the initiation of negative-strand DNA synthesis primed by tRNA Lys-3, as well as the elongation of DNA synthesis mediated by HIV-1 reverse transcriptase. CP-94707 can be used in studies related to HIV infection .
Cat. No.: HY-N19736
CAS No.: 142632-33-5
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Cat. No.: HY-187625
CAS No.: 153312-20-0
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Tgg-II-23A is a non-nucleoside HIV-1 reverse transcriptase inhibitor, with an IC50 of 136 μM against HIV-1 NL4-3 reverse transcriptase . Tgg-II-23A exhibits antiviral activity against wild-type HIV-1, but shows reduced activity against TIBO R82150 (HY-19111)-resistant HIV-1 strains carrying reverse transcriptase mutations. Tgg-II-23A does not inhibit the replication of HIV-2. Tgg-II-23A can be used in studies related to HIV-1 infection .
Cat. No.: HY-N17741
CAS No.: 350229-67-3
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Cat. No.: HY-131612
CAS No.: 19316-85-9
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5'-Azido-5'-deoxythymidine (Compound 7), a nucleoside analogue, is a reverse transcriptase inhibitor. 5'-Azido-5'-deoxythymidine mimics nucleosides and is incorporated into the viral DNA chain to terminate chain elongation, inhibiting viral replication. 5'-Azido-5'-deoxythymidine is promising for research of retroviral infection diseases such as AIDS .
Cat. No.: HY-N17718
CAS No.: 83543-37-7
Synonyms: 3-[8'(Z), 11'(Z), 14'-Pentadecatrienyl] catechol
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Cat. No.: HY-135210
CAS No.: 223393-69-9
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V-165 is an inhibitor of HIV Integrase and HIV Reverse transcriptase, with an IC50 value of 3.8 μM against HIV integrase and an IC50 value of 4.8 μM against HIV reverse transcriptase. V-165 inhibits HIV-1 replication. V-165 can be used in studies related to immunodeficiency virus infections .
Cat. No.: HY-179437
anti-HIV agent 1 (compound 10i) is a potent antiviral agent with anti-HIV activity (IC50 = 10.6 nM). anti-HIV agent 1 exhibits moderate to no inhibitory activity against RT mutant strains, but maintains their activity against wild-type viruses. anti-HIV agent 1 strongly shows dual inhibition of the viral attachment and reverse transcriptase phases of the viral life cycle. anti-HIV agent 1 can be used for HIV infection research .
Cat. No.: HY-183886
CAS No.: 136816-67-6
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U 80493 is a HIV-1 reverse transcriptase inhibitor with IC50 of 20 μM. U 80493 can be used for the research of acquired immunodeficiency syndrome .
Cat. No.: HY-N17392
CAS No.: 2771017-28-6
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Artoheteronin is a prenylated coumarin found in the fruits of Artocarpus heterophyllus. Artoheteronin can inhibit HIV-1 reverse transcriptase activity with an EC50 of 0.18 μM. Artoheteronin shows anti-inflammatory activity and inhibits nitric oxide production. Artoheteronin can be used for the researches of HIV infection and inflammatory disease .
Cat. No.: HY-N21815
CAS No.: 134332-63-1
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Cat. No.: HY-182474
CAS No.: 352548-47-1
Synonyms: Indolopyridone-1
Research Areas:
INDOPY-1 (Indolopyridone-1) is a selective, reversible, and competitive HIV-1 reverse transcriptase inhibitor. INDOPY-1 reversibly binds to the active site of reverse transcriptase. INDOPY-1 inhibits DNA synthesis. INDOPY-1 exhibits antiviral activity against various retroviruses, including HIV-1 IIIB, HIV-1 HXB2 K103N Y181C, HIV-2 ROD, and SIV Mac251. INDOPY-1 can be used in the research of immunodeficiency virus infection .
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Cat. No.: HY-189211
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NNRT-IN-17 is a non-nucleoside HIV-1 Reverse Transcriptase inhibitor with an IC50 of 0.095 μM. NNRT-IN-17 exerts its inhibitory effect by binding to the NNRTI binding pocket and adjacent sites, and exhibits antiviral activity against wild-type and multiple NNRTI-resistant mutant strains. NNRT-IN-17 can be used for the study of HIV-1 infection (AIDS) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
