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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
171 Results for "
ErbB2
" in MedChemExpress (MCE) Product Catalog:
Products (171)
171 Results for "ErbB2" in MCE Product Catalog:
Cat. No.: HY-P86166
Synonyms: Receptor tyrosine-protein kinase ErbB-2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185ErbB2; CD antigen CD340;
Cat. No.: HY-P86719
Synonyms: Erb-B2 Receptor Tyrosine Kinase 2; NGL; NEU; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2; Tyrosine Kinase-Type Cell Surface Receptor HER2; Neuro/Glioblastoma Derived Oncogene Homolog; Human Epidermal Growth Factor Receptor 2; Metastatic Lymph Node Gene 19 Protein; Proto-Oncogene C-ErbB-2; Proto-Oncogene Neu; EC 2.7.10.1; P185ErbB2; MLN 19; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2; V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncoprotein 2; Neuroblastoma/Glioblastoma Derived Oncogene Homolog; Receptor Tyrosine-Protein Kinase ErbB-2; C-Erb B2/Neu Protein; CD340 Antigen; Herstatin; EC 2.7.10; CD340; HER-2; MLN19; TKR1;
Cat. No.: HY-P86719A
Synonyms: Erb-B2 Receptor Tyrosine Kinase 2; NGL; NEU; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2; Tyrosine Kinase-Type Cell Surface Receptor HER2; Neuro/Glioblastoma Derived Oncogene Homolog; Human Epidermal Growth Factor Receptor 2; Metastatic Lymph Node Gene 19 Protein; Proto-Oncogene C-ErbB-2; Proto-Oncogene Neu; EC 2.7.10.1; P185ErbB2; MLN 19; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 2; V-Erb-B2 Erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/Glioblastoma Derived Oncogene Homolog; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncoprotein 2; Neuroblastoma/Glioblastoma Derived Oncogene Homolog; Receptor Tyrosine-Protein Kinase ErbB-2; C-Erb B2/Neu Protein; CD340 Antigen; Herstatin; EC 2.7.10; CD340; HER-2; MLN19; TKR1;
Cat. No.: HY-W740576
CAS No.: 169564-26-5
Target:
Research Areas:
7-Descarbamoyl-17-amino geldanamycin is a Geldanamycin (HY-15230) derivative. 7-Descarbamoyl-17-amino geldanamycin exerts very low activity in depleting p185erbB-2 protein in human breast cancer cells in vitro .
Cat. No.: HY-P991243
Cat. No.: HY-P70841
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ErbB4; Proto-Oncogene-Like Protein C-ErbB-4; Erb-B2 Receptor Tyrosine Kinase 4; P180ErbB4; HER4; V-Erb-A Avian Erythroblastic Leukemia Viral Oncogene Homolog-Like 4; ALS19; Avian Erythroblastic Leukemia Viral (V-Erb-B2) Oncogene Homolog 4; V-Erb-B2 Avian
Species:
Human
Source:
HEK293
Cat. No.: HY-P73035
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ErbB4; Proto-Oncogene-Like Protein C-ErbB-4; Erb-B2 Receptor Tyrosine Kinase 4; P180ErbB4; HER4; V-Erb-A Avian Erythroblastic Leukemia Viral Oncogene Homolog-Like 4; ALS19; Avian Erythroblastic Leukemia Viral (V-Erb-B2) Oncogene Homolog 4; V-Erb-B2 Avian
Species:
Human
Source:
HEK293
Cat. No.: HY-P73036
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ErbB4; Proto-Oncogene-Like Protein C-ErbB-4; Erb-B2 Receptor Tyrosine Kinase 4; P180ErbB4; HER4; V-Erb-A Avian Erythroblastic Leukemia Viral Oncogene Homolog-Like 4; ALS19; Avian Erythroblastic Leukemia Viral (V-Erb-B2) Oncogene Homolog 4; V-Erb-B2 Avian
Species:
Rat
Source:
HEK293
Cat. No.: HY-P73037
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ErbB4; Proto-Oncogene-Like Protein C-ErbB-4; Erb-B2 Receptor Tyrosine Kinase 4; P180ErbB4; HER4; V-Erb-A Avian Erythroblastic Leukemia Viral Oncogene Homolog-Like 4; ALS19; Avian Erythroblastic Leukemia Viral (V-Erb-B2) Oncogene Homolog 4; V-Erb-B2 Avian
Species:
Rat
Source:
HEK293
Cat. No.: HY-P78454
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: ErbB4; Proto-Oncogene-Like Protein C-ErbB-4; Erb-B2 Receptor Tyrosine Kinase 4; P180ErbB4; HER4; V-Erb-A Avian Erythroblastic Leukemia Viral Oncogene Homolog-Like 4; ALS19; Avian Erythroblastic Leukemia Viral (V-Erb-B2) Oncogene Homolog 4; V-Erb-B2 Avian
Species:
Human
Source:
HEK293
Cat. No.: HY-P700733
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ErbB4; Proto-Oncogene-Like Protein C-ErbB-4; Erb-B2 Receptor Tyrosine Kinase 4; P180ErbB4; HER4; V-Erb-A Avian Erythroblastic Leukemia Viral Oncogene Homolog-Like 4; ALS19; Avian Erythroblastic Leukemia Viral (V-Erb-B2) Oncogene Homolog 4; V-Erb-B2 Avian
Species:
Human
Source:
HEK293
Cat. No.: HY-P701234
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: ErbB4; Proto-Oncogene-Like Protein C-ErbB-4; Erb-B2 Receptor Tyrosine Kinase 4; P180ErbB4; HER4; V-Erb-A Avian Erythroblastic Leukemia Viral Oncogene Homolog-Like 4; ALS19; Avian Erythroblastic Leukemia Viral (V-Erb-B2) Oncogene Homolog 4; V-Erb-B2 Avian
Species:
Human
Source:
HEK293
Cat. No.: HY-P702752
Purity: ≥ 70%, as determined by reducing SDS-PAGE.
Synonyms: ErbB4; Proto-Oncogene-Like Protein C-ErbB-4; Erb-B2 Receptor Tyrosine Kinase 4; P180ErbB4; HER4; V-Erb-A Avian Erythroblastic Leukemia Viral Oncogene Homolog-Like 4; ALS19; Avian Erythroblastic Leukemia Viral (V-Erb-B2) Oncogene Homolog 4; V-Erb-B2 Avian
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P703899
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: ErbB4; Proto-Oncogene-Like Protein C-ErbB-4; Erb-B2 Receptor Tyrosine Kinase 4; P180ErbB4; HER4; V-Erb-A Avian Erythroblastic Leukemia Viral Oncogene Homolog-Like 4; ALS19; Avian Erythroblastic Leukemia Viral (V-Erb-B2) Oncogene Homolog 4; V-Erb-B2 Avian
Species:
Human
Rhesus Macaque
Source:
HEK293
Cat. No.: HY-P705611
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ErbB4; Proto-Oncogene-Like Protein C-ErbB-4; Erb-B2 Receptor Tyrosine Kinase 4; P180ErbB4; HER4; V-Erb-A Avian Erythroblastic Leukemia Viral Oncogene Homolog-Like 4; ALS19; Avian Erythroblastic Leukemia Viral (V-Erb-B2) Oncogene Homolog 4; V-Erb-B2 Avian
Species:
Mouse
Source:
HEK293
Cat. No.: HY-10325R
CAS No.: 194423-06-8
Synonyms: EKI-785 (Standard); WAY-EKI 785 (Standard)
Target:
Research Areas:
CL-387785 (EKI-785; WAY-EKI 785) (Standard) is the analytical standard of CL-387785 (HY-10325). This product is intended for research and analytical applications. CL-387785 is an orally active EGFR inhibitor with an IC50 of 370 pM. CL-387785 inhibits EGF-stimulated EGFR autophosphorylation with an IC50 of approximately 5 nM. CL-387,785 exerts selective inhibition on cell lines overexpressing EGFR or c-erbB-2, whereas it shows weak inhibitory effects on cell lines with low expression of these two receptors. CL-387785 effectively induces cell cycle arrest and apoptosis. CL-387785 can be used for the research of non-small cell lung cancer and autosomal recessive polycystic kidney disease.
Cat. No.: HY-186321
CAS No.: 501124-40-9
Synonyms: KF25706
Radicicol 6-oxime (KF25706) is an Hsp90 inhibitor with an EC50 of 5.5 nM against human Hsp90. Radicicol 6-oxime binds to Hsp90 and disrupts its chaperone function, leading to destabilization and depletion of Hsp90-associated signaling molecules. Radicicol 6-oxime depletes Hsp90-associated signaling proteins such as Raf-1, v-src, p185erbB2, Cdk4, and mutant p53, thereby inhibiting K-ras and v-src signaling pathways. Radicicol 6-oxime exhibits antiproliferative activity against various tumor cells. Radicicol 6-oxime inhibits tumor growth in mouse tumor xenograft models. Radicicol 6-oxime can be used for research on breast cancer, colon cancer, and vulvar epidermoid carcinoma .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
