20 Results for "

12-O-tetradecanoylphorbol-13-acetate

" in MedChemExpress (MCE) Product Catalog:
Products (20)

20 Results for "12-O-tetradecanoylphorbol-13-acetate" in MCE Product Catalog:

Cat. No.: HY-P3469A
Target:  

GCGR

Research Areas:  

Metabolic Disease

Dasiglucagon acetate is a human glucagon analog, and can increase plasma glucose. Dasiglucagon can be used in hypoglycemia research .
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Cat. No.: HY-107260
CAS No.: 98665-16-8
Purity:  99.78%
Synonyms: Lucidenic acid D2
Lucidenic acid D is a highly oxidized triterpenoid with anti-inflammatory and antiviral activities. Lucidenic acid D attenuates lipopolysaccharide-induced release of proinflammatory cytokines and nitric oxide, reduces the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2), and inhibits skin inflammation. Lucidenic acid D suppresses 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced expression of Epstein-Barr virus (EBV) early antigen and maintains the viability of Raji cells. Lucidenic acid D can be used in studies of cancer chemoprevention .
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Cat. No.: HY-B1231
CAS No.: 543-15-7
Synonyms: RP-2831 hydrochloride
Heptaminol (RP-2831) hydrochloride is a vasoconstrictor used in the study of hypotension, especially orthostatic hypotension. Heptaminol is also a skin cancer proliferation inhibitor that inhibits immune inflammation induced by the tumor promoting factor 12-O-tetradecanoylphorbol-13-acetate (TPA) in an NO-dependent manner. Heptaminol also acts as a sympathomimetic amine, exerting indirect sympathetic effects. Heptaminol is also an antagonist of catecholamine release and uptake and can increase intracellular free calcium levels .
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Cat. No.: HY-N7691
CAS No.: 389122-01-4
Synonyms: Karounidiol dibenzoate
3,29-O-Dibenzoyloxykarounidiol (Karounidiol dibenzoate) is a multiflorane-type triterpene benzoate that inhibits Phorbol 12-myristate 13-acetate (TPA) (HY-18739)-induced Epstein-Barr virus early antigen activation and exhibits tumor-promotion inhibitory activity. 3,29-O-Dibenzoyloxykarounidiol is used in cancer-related research .
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Cat. No.: HY-N7041
11-Oxomogroside IIa (11-oxomogroside II A1) is a cucurbitane glycoside extracted from the fruits of Siraitia grosVenorii. 11-Oxomogroside IIa has inhibitory effects against the Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA), shows weak inhibitory effects on activation of (+/-)-(E)-methyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3-hexemide (NOR 1), a nitric oxide (NO) donor .
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Cat. No.: HY-N4024
CAS No.: 128397-09-1
Hyptadienic acid is a triterpene acid that can be isolated from the leaves of Perilla frutescens. Hyptadienic acid inhibits 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice with an ID50 value of 0.13 mg/ear. Hyptadienic acid can be used for the research of inflammation .
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Cat. No.: HY-N11009
CAS No.: 942612-74-0
11-Oxomogroside II A1 (compound 7) is an oxidized cucurbitin. It can be isolated from the ethanol extract of Rohanberry fruit. 11-Oxomogroside II A1 inhibits the activation of Epstein-Barr virus (EBV) early antigen (EBV-EA) induced by 12-O-tetradecanoylphorbol-13-acetate (TPA). 11-Oxomogroside II A1 also weakly inhibits the activation of (±)-(E)-methyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3-hexemide (NOR 1), a nitric oxide (NO) donor .
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Cat. No.: HY-114809
CAS No.: 126455-04-7
AL-1 is a potent O2 - generation inhibitor (IC50 = 7.6 μM) through the inhibition of leukocytic NADPH oxidase. AL-1 inhibits 12-O-Tetradecanoylphorbol-13-acetate (TPA)-induced H2O2 production. AL-1 reduces tumor incidence in ICR mouse skin. AL-1 can be used for research on oxidative stress-related diseases including cancer .
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Cat. No.: HY-108602
CAS No.: 143370-84-7
Target:  

PKC

Research Areas:  

Cancer

Bryostatin 3, a macrocyclic lactone, is a protein kinase C activator, with a Ki of 2.75 nM. Bryostatin 3 can block 12-O-tetradecanoylphorbol-13-acetate (TPA) inhibition of cell proliferation, yet did not block TPA-enhanced cell-substratum adhesion .
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Cat. No.: HY-126198
CAS No.: 75358-37-1
Synonyms: McN-3935
Target:  

Antibiotic

Research Areas:  

Metabolic Disease

Linogliride (MCN-3935) is an antidiabetic agent. Linogliride (100 μM) does not affect insulin secretion in the absence of glucose, but has a significant insulinotropic effect in the presence of 5.5 mM glucose .
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Cat. No.: HY-126198A
CAS No.: 78782-47-5
Synonyms: McN-3935 fumarate
Target:  

Antibiotic

Research Areas:  

Metabolic Disease

Linogliride (MCN-3935) fumarate is an antidiabetic agent. Linogliride fumarate (100 μM) does not affect insulin secretion in the absence of glucose, but has a significant insulinotropic effect in the presence of 5.5 mM glucose .
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Cat. No.: HY-100983R
CAS No.: 108930-17-2
Target:  

Reference Standards PKC

Research Areas:  

Cancer

Protein kinase inhibitor H-7 (dihydrochloride) (Standard) is the analytical standard of Protein kinase inhibitor H-7 (dihydrochloride). This product is intended for research and analytical applications. Protein kinase inhibitor H-7 dihydrochloride is a potent PKC (protein kinase C) inhibitor. At 100 μM, Protein kinase inhibitor H-7 dihydrochloride completely inhibits both TPA (skin tumour promoter, 12-O-tetradecanoylphorbol-13-acetate) and phospholipase C-induced ODC (ornithine decarboxylase) .
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Cat. No.: HY-B1231R
CAS No.: 543-15-7
Synonyms: RP-2831 hydrochloride (Standard)
Heptaminol (hydrochloride) (Standard) is the analytical standard of Heptaminol (hydrochloride). This product is intended for research and analytical applications. Heptaminol (RP-2831) hydrochloride is a vasoconstrictor used in the study of hypotension, especially orthostatic hypotension. Heptaminol is also a skin cancer proliferation inhibitor that inhibits immune inflammation induced by the tumor promoting factor 12-O-tetradecanoylphorbol-13-acetate (TPA) in an NO-dependent manner. Heptaminol also acts as a sympathomimetic amine, exerting indirect sympathetic effects. Heptaminol is also an antagonist of catecholamine release and uptake and can increase intracellular free calcium levels .
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Cat. No.: HY-P4908
CAS No.: 1115-52-2
Synonyms: DCE-GS
Research Areas:  

Cardiovascular Disease

S-(1,2-Dicarboxyethyl) glutathione (DCE-GS) is a platelet aggregation inhibitor. S-(1,2-Dicarboxyethyl) glutathione can be isolated from animal tissues and baker's yeast. S-(1,2-Dicarboxyethyl) glutathione acts as an anticoagulant without chelating calcium ions .
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Cat. No.: HY-N17354
CAS No.: 28333-13-3
Glycocitrine II is an acridone alkaloid. Glycocitrine II can be isolated from the Rutaceous plants. Glycocitrine II inhibits 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced EBV-EA activation .
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Cat. No.: HY-183367
CAS No.: 1504587-21-6
Research Areas:  

Inflammation/Immunology

Anti-inflammatory agent 115 is a potent anti-inflammatory agent. Anti-inflammatory agent 115 reduces secretion of myeloperoxidase (MPO), TNF-α, IL-1β, and IL-6. Anti-inflammatory agent 115 decreases ear tissue thickness and neutrophil infiltration in 12-O-tetradecanoylphorbol-13-acetate (TPA) (HY-18739)-induced topical edema in mice. Anti-inflammatory agent 115 can be used for the research of inflammatory diseases .
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Cat. No.: HY-P4908A
Synonyms: DCE-GS acetate
Research Areas:  

Cardiovascular Disease

S-(1,2-Dicarboxyethyl) glutathione acetate (DCE-GS acetate) is a platelet aggregation inhibitor. S-(1,2-Dicarboxyethyl) glutathione acetate can be isolated from animal tissues and baker's yeast. S-(1,2-Dicarboxyethyl) glutathione acetate acts as an anticoagulant without chelating calcium ions .
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Cat. No.: HY-N17638
CAS No.: 942612-72-8
7-Oxomogroside V is a cucurbitane-type glycoside isolated from the fruits of Siraitia grosvenorii. 7-Oxomogroside V inhibits the activation of Epstein-Barr virus early antigen (EBV-EA) induced by TPA (HY-18739). 7-Oxomogroside V also exerts weak inhibitory effects on the activation of the nitric oxide donor NOR 1. 7-Oxomogroside V is applicable to tumor-related research .
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Cat. No.: HY-N9752
CAS No.: 942615-25-0
Mogroside II B is a cucurbitane-type glycoside with a sweet taste in water. Mogroside II B inhibits the activation of Epstein Barr virus early antigen (EBV-EA) induced by Phorbol 12-myristate 13-acetate (TPA) (HY-18739). Mogroside II B exerts weak inhibitory effects on the activation of the nitric oxide (NO) donor (NOR1) .
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Cat. No.: HY-N18117A
CAS No.: 1429747-10-3
23-Hydroxyohchininolide is a limonoid found in the leaves of Melia azedarach L.. 23-Hydroxyohchininolide inhibits LPS (HY-D1056)-induced NO production and exerts cytotoxic activity against human leukemia and stomach cancer cells. 23-Hydroxyohchininolide inhibits TPA (HY-18739)-induced Epstein-Barr virus early antigen activation. 23-Hydroxyohchininolide can be used for the research of cancer, infection and inflammatory disease .
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