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Results for "

18A

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Bacterial (3) Bcr-Abl (1) Biochemical Assay Reagents (2) Caspase (1) Drug Intermediate (1) Epigenetic Reader Domain (1) ERK (1) Ferroptosis (1) Fluorescent Dye (1) G-quadruplex (1) Glutathione Peroxidase (1) Guanylate Cyclase (1) HCV (1) HIV (1) Interleukin Related (1) JNK (1) Kinesin (17) Ligands for E3 Ligase (1) MicroRNA (16) Microtubule/Tubulin (10) NO Synthase (1) p38 MAPK (2) Parasite (1) PI3K (1) PPAR (1) Prostaglandin Receptor (1) PROTACs (1) Reactive Oxygen Species (ROS) (2) Small Interfering RNA (siRNA) (18) SOS1 (1) Src (1) Toll-like Receptor (TLR) (1) α-synuclein (1)
By Research Areas:	Cancer (41) Cardiovascular Disease (2) Infection (6) Inflammation/Immunology (1) Neurological Disease (3)
Oligonucleotides:	miRNA mimics (4) miRNA antagomirs (4) miRNA agomirs (4) MicroRNAs (16) Rat Pre-designed siRNA Sets (5) Mouse Pre-designed siRNA Sets (5) miRNA inhibitors (4) Human Pre-designed siRNA Sets (8) siRNAs (18)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-153065

KIF18A-IN-6	Kinesin Microtubule/Tubulin	Cancer
KIF18A-IN-6 (Compound 134) is an orally active *KIF18A* inhibitor with an IC₅₀ of 0.016 μM against KIF18A microtubule-dependent ATPase activity .

HY-153066

VLS-1272 KIF18A-IN-7	Kinesin Microtubule/Tubulin Apoptosis	Cancer
VLS-1272 (Compound 22) is an orally active *KIF18A* inhibitor that binds to the KIF18A-microtubule complex in an ATP-noncompetitive manner (IC₅₀ = 41 nM), blocking its ATPase activity and inhibiting microtubule translocation. This leads to abnormal accumulation of KIF18A at spindle poles, disrupting chromosome alignment and inducing mitotic arrest and apoptosis in CIN ^High tumor cells (e.g., ovarian cancer OVCAR-3, breast cancer JIMT-1). VLS-1272 is a promising candidate for anti-tumor research .

HY-135009

2-Di-1-ASP DASPI	G-quadruplex	Others
2-Di-1-ASP (DASPI; Compound 18a) is a mono-stryryl dye, and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. 2-Di-1-ASP is selective for G-quadruplex (G4) and double-stranded DNA .

HY-145034

KIF18A-IN-1 1 Publications Verification	Kinesin	Cancer
KIF18A-IN-1 is an inhibitor of the mitotic kinesin *KIF18A* with anti-tumor activity. KIF18A targeted inhibitors may activate mitotic checkpoints and selectively kill chromosomally unstable cancer cells .

HY-W001294

(R)-(-)-N-Boc-3-pyrrolidinol	Biochemical Assay Reagents Drug Intermediate	Cardiovascular Disease
(R)-(-)-N-Boc-3-pyrrolidinol (Compound 22a) is a key intermediate for the preparation of Compound 18a and subsequent ion channel modulating compounds. (R)-(-)-N-Boc-3-pyrrolidinol can be used in the research of cardiac arrhythmia .

HY-162937

KIF18A-IN-13	Kinesin Microtubule/Tubulin	Cancer
KIF18A-IN-13 (Compound 16) is an effective and orally active inhibitor of *KIF18A* with anticancer activity in vivo. KIF18A-IN-13 can be utilized for research in ovarian cancer .

HY-110253

*18A* HIV-1 inhibitor 18A	HIV	Infection
18A (HIV-1 inhibitor 18A) is a reversible broad-spectrum HIV-1 inhibitor. 18A exhibits broad inhibitory activity against multiple HIV-1 strains by blocking the function of Env .

HY-R00352

*hsa-miR-18a-3p mimic*	MicroRNA	Cancer
hsa-miR-18a-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-18a-3p mimic hsa-miR-18a-3p mimic

HY-145802

KIF18A-IN-2	Kinesin Microtubule/Tubulin	Cancer
KIF18A-IN-2 is a potent *KIF18A* inhibitor (IC₅₀=28 nM). KIF18A-IN-2 causes significant mitotic arrest and increases the number of mitotic cells in tumor tissues. KIF18A-IN-2 can be used for researching cancer .

HY-145803

KIF18A-IN-3	Kinesin Microtubule/Tubulin	Cancer
KIF18A-IN-3 is a potent *KIF18A* inhibitor (IC₅₀=61 nM). KIF18A-IN-3 causes significant mitotic arrest and increases the number of mitotic cells in tumor tissues. KIF18A-IN-3 can be used for researching cancer .

HY-RS13043

SLC18A1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SLC18A1 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC18A1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SLC18A1 Human Pre-designed siRNA Set A SLC18A1 Human Pre-designed siRNA Set A

HY-162106

PROTAC GPX4 degrader-2	Ferroptosis PROTACs Glutathione Peroxidase	Cancer
PROTAC GPX4 degrader-2 (compound 18a) is a proteolysis targeting chimeras (PROTACs) that can degrade glutathione peroxidase 4 (GPX4), with the DC_{50, 48h} value of 1.68 μM. PROTAC GPX4 degrader-2 induces the accumulation of lipid peroxides and mitochondrial depolarization, subsequently triggering ferroptosis. PROTAC GPX4 degrader-2 has anti-proliferative effect .

HY-E71264

*β-Acetylglucosaminidase 18A, Bacteroides thetaiotaomicron*	Biochemical Assay Reagents	Others
β-Acetylglucosaminidase 18A, Bacteroides thetaiotaomicron (EC 3.2.1.96), is an enzyme from Bacteroides thetaiotaomicron that participates in the endohydrolysis of the diacetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins containing the (Man (GlcNAc) (2) ) Asn-structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact. Recombinant BtAcp18A (GH18) , purified from Escherichia coli, is a single domain family 18 Glycoside Hydrolase (GH18) .

HY-R00353

*hsa-miR-18a-5p mimic*	MicroRNA	Cancer
hsa-miR-18a-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-18a-5p mimic hsa-miR-18a-5p mimic

HY-R02722

*mmu-miR-18a-3p mimic*	MicroRNA	Cancer
mmu-miR-18a-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

mmu-miR-18a-3p mimic mmu-miR-18a-3p mimic

HY-R04263

*rno-miR-18a-3p mimic*	MicroRNA	Cancer
rno-miR-18a-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

rno-miR-18a-3p mimic rno-miR-18a-3p mimic

HY-RI02722

*mmu-miR-18a-3p inhibitor*	MicroRNA	Cancer
mmu-miR-18a-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

mmu-miR-18a-3p inhibitor mmu-miR-18a-3p inhibitor

HY-P11250

HVF18-a3-d	Bacterial NO Synthase Interleukin Related Reactive Oxygen Species (ROS) Toll-like Receptor (TLR) ERK JNK p38 MAPK	Infection Inflammation/Immunology
HVF18-a3-d is an antimicrobial peptide. HVF18-a3-d reduces NO production. HVF18-a3-d inhibits the production of TNF-α and IL-6, reduces ROS production, and suppresses the TLR4 signaling pathway, as well as LPS-induced phosphorylation of ERK, JNK, and p38 MAPK. HVF18-a3-d exhibits antimicrobial activity against a variety of bacteria by disrupting their outer and inner membranes. HVF18-a3-d protects mice from fatal septic shock induced by Acinetobacter baumannii resistant to Carbapenem. HVF18-a3-d shows anti-inflammatory and antioxidant effects .

HY-178511

KIF18A-IN-17	Kinesin	Cancer
KIF18A-IN-17 (Example 37A) is a *KIF18A* inhibitor with racemic form with an IC₅₀ of 48 nM. KIF18A-IN-17 exhibits anti-proliferative activity against HT29 cells. KIF18A-IN-17 can be used for the study of cancers such as breast cancer and ovarian cancer .

HY-D2201

Fluorescent ACKR3 antagonist 1	Fluorescent Dye	Cancer
Fluorescent ACKR3 antagonist 1(compound 18a) is a atypical chemokine receptor 3 antagonist .

HY-RI00352A

*hsa-miR-18a-3p antagomir*	MicroRNA	Cancer
hsa-miR-18a-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-18a-3p antagomir hsa-miR-18a-3p antagomir

HY-49514

VHL Ligand intermediate-1	Ligands for E3 Ligase SOS1	Cancer
VHL Ligand intermediate-1 (intermediate 18a) is an intermediate in the synthesis of VHL E3 ubiquitin ligase ligand and can be used to synthesize PROTACs .

HY-149349

MtUng-IN-1	Bacterial	Infection Cancer
MtUng-IN-1 (Compound 18a) is a Uracil DNA glycosylase of Mycobacterium (MtUng) inhibitor (IC₅₀: 300 μM). MtUng-IN-1 can be used for research of cancers and infectious diseases .

HY-101268

CHMFL-ABL-053	Bcr-Abl Src p38 MAPK	Cancer
CHMFL-ABL-053 (Compound 18a) is a potent, selective, and orally available BCR-ABL, SRC and p38 kinase inhibitor with IC₅₀ values of 70, 90 and 62 nM against ABL1, SRC and p38, respectively .

HY-146438

PPARγ agonist 3	PPAR	Cancer
PPARγ agonist 3 (Compound 18a) is a potent and selective agonist of PPARγ. PPARγ agonist 3 is not cytotoxic neither on non-resistant nor on resistant cells. PPARγ agonist 3 exerts antitumor potency only in combination with Imatinib .

HY-147763

HCV-IN-39	HCV	Infection
HCV-IN-39 (Compound 18a) is a potent hepatitis C virus (HCV) nucleoside inhibitor with EC₅₀ values of 0.644, 0.952 and 0.154 μM against GT1a, GT1b and GT1b CES1 replicons .

HY-173594

TarO-IN-1	Bacterial	Infection
TarO-IN-1 (Compound 18a) is a TarO inhibitor and has antibacterial activity. TarO-IN-1 has β-lactam sensitizing and anti-biofilm activities against MRSA. TarO-IN-1 can be used for research of β-lactam resistance .

HY-142697

SGC agonist 1	Guanylate Cyclase	Cardiovascular Disease
SGC agonist 1 is a potent agonist of soluble guanylate cyclase (SGC). SGC agonist 1 improves solubility combined with high cell permeability. SGC agonist 1 has the potential for the research of cardiovascular disease (extracted from patent WO2016030354A1, compound 18A) .

HY-163543

Progranulin modulator-2	Epigenetic Reader Domain	Neurological Disease
Progranulin modulator-2 (compound 18A) is a bromodomain and extra-terminal domain (BET) inhibitor. Progranulin modulator-2 enhances PGRN expression by targeting members of the BET protein family. Progranulin modulator-2 can be used to study the role of BET protein in neurodevelopment, neuroplasticity and neurodegeneration .

HY-147549

Antitrypanosomal agent 6	Parasite	Infection
Antitrypanosomal agent 6 (compound 18a) is a potent and antitrypanosomal agent with favorable ADME properties. Antitrypanosomal agent 6 is > 2-fold more potent against *Trypanosoma brucei* (T. brucei) than Nifurtimox, with an IC₅₀ value of 0.47 μM. Antitrypanosomal agent 6 has strong interaction to DNA and can bind with high selectivity to AT-rich DNA .

HY-156018

PI3Kα-IN-13	PI3K	Cancer
PI3Kα-IN-13 (Compound 18a) is a PI3Kα inhibitor (IC₅₀: 2.5 nM). PI3Kα-IN-13 induces tumor cell apoptosis. PI3Kα-IN-13 inhibits cancer cell proliferation with IC₅₀s of 0.75 μM (MCF-7), 3.79 μM (HCT-116), 13.71 μM (MDA-MB-231), 9.85 μM (SW620), respectively. PI3Kα-IN-13 inhibits tumor cell colony formation, migration and invasion .

HY-156898

NPT100-18A	α-synuclein Caspase Reactive Oxygen Species (ROS)	Neurological Disease
NPT100-18A is an αSyn oligomerization inhibitor. NPT10018A rescues cleaved caspase-3 levels to control levels. NPT10018A attenuates mitochondrial oxidative stress probe levels in a compartment-specific manner and, at higher concentrations, increases ATP signals. NPT100-18A can be used for the study of Parkinson’s disease (PD) .

HY-RI00352

*hsa-miR-18a-3p inhibitor*	MicroRNA	Cancer
hsa-miR-18a-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-18a-3p inhibitor hsa-miR-18a-3p inhibitor

HY-RI04263

*rno-miR-18a-3p inhibitor*	MicroRNA	Cancer
rno-miR-18a-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

rno-miR-18a-3p inhibitor rno-miR-18a-3p inhibitor

HY-RI00353

*hsa-miR-18a-5p inhibitor*	MicroRNA	Cancer
hsa-miR-18a-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-18a-5p inhibitor hsa-miR-18a-5p inhibitor

HY-162531

KIF18A-IN-9	Kinesin Microtubule/Tubulin	Cancer
KIF18A-IN-9 (Compound 1) is a potent *KIF18A* inhibitor, with an IC₅₀ value of 3.8 nM. KIF18A-IN-9 has anticancer activity, with IC₅₀ values of less than 100 nM in OVCAR3 and MDA-MB-157 cells .

HY-158683

KIF18A-IN-11	Kinesin Microtubule/Tubulin	Cancer
KIF18A-IN-11 (Compound 13) is a potent *KIF18A* inhibitor, with IC₅₀ values of less than 100 nM in OVCAR3 and MDA-MB-157 cells. KIF18A-IN-11 can be used for the research of cancer .

HY-164979

KIF18A-IN-15	Kinesin	Cancer
KIF18A-IN-15 (Compound Example 36) is a *KIF18A* inhibitor, available in two forms, EX36-A and its enantiomer EX36-B, with IC₅₀s of 0.01-0.1 μM, respectively. EX36-A and EX36-B inhibit OVCAR-3 cells viability with IC₅₀s of 0.01-0.1 μM and 0-0.01 μM, respectively. KIF18A-IN-15 can be used in tumor (e.g. colon, breast, lung) studies .

HY-162532

KIF18A-IN-10	Kinesin Microtubule/Tubulin	Cancer
KIF18A-IN-10 (Compound 24) is a potent *KIF18A* inhibitor, with an IC₅₀ value of 23.8 nM. KIF18A-IN-10 has anticancer activity, with IC₅₀ values of less than 100 nM in OVCAR3 and MDA-MB-157 cells .

HY-158757

KIF18A-IN-12	Kinesin Microtubule/Tubulin	Cancer
KIF18A-IN-12 (compound 9) is a *KIF18A* inhibitor, with an IC₅₀ value of 45.54 nM. KIF18A-IN-12 can be used in cancer research .

HY-164978

KIF18A-IN-14	Kinesin	Cancer
KIF18A-IN-14 (Compound Example 81) is a *KIF18A* inhibitor. KIF18A-IN-14 is available in two forms, EX81-A and its enantiomer EX81-B. EX81-A and EX81-B inhibit OVCAR-3 cells viability with IC₅₀s of 0-0.01 μM and 0.01-0.1 μM, respectively. KIF18A-IN-14 can be used in tumor (e.g. colon, breast, lung) studies .

HY-164980

KIF18A-IN-16	Kinesin	Cancer
KIF18A-IN-16 (Compound 15) is a fused ring *KIF18A* inhibitor. KIF18A-IN-16 can be used in oncology (e.g., colon, breast, lung cancer) studies .

HY-145827

KIF18A-IN-4	Kinesin Microtubule/Tubulin	Cancer
KIF18A-IN-4 is a moderately potent ATP and microtubule (MT) noncompetitive *KIF18A* inhibitor (IC₅₀=6.16 μM). KIF18A-IN-4 has selectivity against a large panel of mitotic kinesins and kinases, and does not show any direct effects on tubulin assembly. KIF18A-IN-4 exhibits anti-tumor activity .

HY-R04263A

*rno-miR-18a-3p agomir*	MicroRNA	Cancer
rno-miR-18a-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

rno-miR-18a-3p agomir rno-miR-18a-3p agomir

HY-R00353A

*hsa-miR-18a-5p agomir*	MicroRNA	Cancer
hsa-miR-18a-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-18a-5p agomir hsa-miR-18a-5p agomir

HY-R00352A

*hsa-miR-18a-3p agomir*	MicroRNA	Cancer
hsa-miR-18a-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-18a-3p agomir hsa-miR-18a-3p agomir

HY-R02722A

*mmu-miR-18a-3p agomir*	MicroRNA	Cancer
mmu-miR-18a-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-18a-3p agomir mmu-miR-18a-3p agomir

HY-RS16612

Kif18a Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Kif18a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Kif18a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Kif18a Mouse Pre-designed siRNA Set A Kif18a Mouse Pre-designed siRNA Set A

HY-RS12170

RPL18A Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
RPL18A Human Pre-designed siRNA Set A contains three designed siRNAs for RPL18A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

RPL18A Human Pre-designed siRNA Set A RPL18A Human Pre-designed siRNA Set A

HY-RS07267

KIF18A Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
KIF18A Human Pre-designed siRNA Set A contains three designed siRNAs for KIF18A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

KIF18A Human Pre-designed siRNA Set A KIF18A Human Pre-designed siRNA Set A

Cat. No.	Product Name	Type

HY-135009

2-Di-1-ASP DASPI	Fluorescent Dye
2-Di-1-ASP (DASPI; Compound 18a) is a mono-stryryl dye, and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. 2-Di-1-ASP is selective for G-quadruplex (G4) and double-stranded DNA .

HY-D2201

Fluorescent ACKR3 antagonist 1	Fluorescent Dye
Fluorescent ACKR3 antagonist 1(compound 18a) is a atypical chemokine receptor 3 antagonist .

Cat. No.	Product Name	Target	Research Area

HY-P11250

HVF18-a3-d	Bacterial NO Synthase Interleukin Related Reactive Oxygen Species (ROS) Toll-like Receptor (TLR) ERK JNK p38 MAPK	Infection Inflammation/Immunology
HVF18-a3-d is an antimicrobial peptide. HVF18-a3-d reduces NO production. HVF18-a3-d inhibits the production of TNF-α and IL-6, reduces ROS production, and suppresses the TLR4 signaling pathway, as well as LPS-induced phosphorylation of ERK, JNK, and p38 MAPK. HVF18-a3-d exhibits antimicrobial activity against a variety of bacteria by disrupting their outer and inner membranes. HVF18-a3-d protects mice from fatal septic shock induced by Acinetobacter baumannii resistant to Carbapenem. HVF18-a3-d shows anti-inflammatory and antioxidant effects .

Species:	Human (1) Mouse (2)
Tag:	His (3) GST (1)
Source:	HEK293 (1) Sf9 insect cells (1) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P70347

	Collagen alpha-1(XVIII) chain/COL18A1 Protein, Mouse (HEK293, His) rMuCollagen Alpha-1(XVIII) Chain/Endostatin, His; antiangiogenic agent; COL18A1; collagen alpha-1(XVIII)chain; collagen; type XVIII; Endostatin	Mouse	HEK293
	The COL18A1 protein may play a key role in shaping retinal structure and promoting neural tube closure. Its involvement extends to the regulation of extracellular matrix-dependent motility and morphogenesis of endothelial and non-endothelial cells. Collagen alpha-1 (XVIII) chain/COL18A1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Collagen alpha-1(XVIII) chain/COL18A1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P77092

	Syntaxin-BP1 Protein, Human (sf9, His-GST) Syntaxin-binding protein 1; MUNC18-1; N-Sec1; UNC18A; p67	Human	Sf9 insect cells
	Syntaxin-BP1 protein critically regulates synaptic vesicle docking and fusion, binds GTP-binding proteins and ensures efficient neurotransmission. It interacts with syntaxin in a 1:1 ratio and shows specificity for syntaxin 1, 2, and 3 (excluding syntaxin 4). Syntaxin-BP1 Protein, Human (sf9, His-GST) is the recombinant human-derived Syntaxin-BP1 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.

HY-P71084

	S100A4 Protein, Mouse (His) 2 Publications Verification Protein S100-A4; Metastasin; Metastatic cell protein; PEL98; Placental calcium-binding protein; Protein 18A2; Protein Mts1; S100 calcium-binding protein A4; S100a4; Capl; Mts1	Mouse	E. coli
	The S100A4 protein, a calcium-binding protein, regulates cellular processes including motility, angiogenesis, differentiation, apoptosis, and autophagy.It interacts with MYH9 to enhance cell motility and chemotaxis.It modulates TP53 to reduce protein levels and stimulates cytokine production.S100A4 forms homodimers and interacts with PPFIBP1, ANXA2, TP53, CCR5, CXCR3, and FCGR3A, inhibiting FCGR3A phosphorylation.S100A4 Protein, Mouse (His) is the recombinant mouse-derived S100A4 protein, expressed by E.coli , with C-6*His labeled tag.

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Host:	Rat (1) Mouse (12) Rabbit (5)
Reactivity:	Human (15) Rat (10) Mouse (14) human (2)
Application:	IHC-P (11) ICC/IF (7) IF-Tissue (1) IP (5) IHC-F (1) WB (11) FC (5) ELISA (6)
Isotype:	IgG (5) IgG1 (7) IgG2a (2) IgG2b (1)
Conjugation:	Non-conjugated (18)
Clonality:	Monoclonal (10) Recombinant (5)
Modification:	Unmodified (12)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P84473

	RPL18A Antibody (YA4170) L18A	WB, IHC-P, ELISA	Human, Mouse
	RPL18A Antibody (YA4170) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RPL18A.

HY-P84473A

	RPL18A Antibody (YA4170)(PBS only) L18A	WB, IHC-P, ELISA	Human, Mouse
	RPL18A Antibody (YA4170) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to RPL18A.

HY-P89615

	*Aldehyde dehydrogenase 18-A1/ALDH18A1 Antibody (YA8959)*	WB, IP, ELISA	human
	Aldehyde dehydrogenase 18-A1/ALDH18A1 Antibody (YA8959) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Aldehyde dehydrogenase 18-A1/ALDH18A1.

HY-P89562

	COL18A1 Antibody (YA8906)	WB, ICC/IF, IF-Tissue, IP, ELISA	human
	COL18A1 Antibody (YA8906) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to COL18A1.

HY-P89155

	MYO18A Antibody (YA8839) MAJN; MYSPDZ; SP-R210; SPR210	IHC-P	Human, Mouse, Rat
	MYO18A Antibody (YA8839) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to MYO18A.

HY-P88094

	SLC18A2 (VMAT2) Antibody (YA7778) SVAT; SVMT; VAT2; VMAT2	IHC-P, ICC/IF, FC	Human, Mouse, Rat
	SLC18A2 (VMAT2) Antibody (YA7778) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SLC18A2 (VMAT2).

HY-P89155A

	MYO18A Antibody (YA8839)(PBS only) MAJN; MYSPDZ; SP-R210; SPR210	IHC-P	Human, Mouse, Rat
	MYO18A Antibody (YA8839) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to MYO18A.

HY-P88094A

	SLC18A2 (VMAT2) Antibody (YA7778)(PBS only) SVAT; SVMT; VAT2; VMAT2	IHC-P, ICC/IF, FC	Human, Mouse, Rat
	SLC18A2 (VMAT2) Antibody (YA7778) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to SLC18A2 (VMAT2).

HY-P81976

	WIPI1 Antibody (YA1721) ATG18; ATG18A; WIPI 1; WIPI-1; WIPI49	WB, IHC-P	Human, Mouse, Rat
	WIPI1 Antibody (YA1721) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to WIPI1.

HY-P82875

	Syntaxin Binding Protein 1 Antibody (YA2620) STXBP1; UNC18A; Syntaxin-binding protein 1; MUNC18-1; N-Sec1; Protein unc-18 homolog 1; Unc18-1; Protein unc-18 homolog A; Unc-18A; p67	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	Syntaxin Binding Protein 1 Antibody (YA2620) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Syntaxin Binding Protein 1.

HY-P84220

	S100A4 Antibody (YA3917) 42A; 18A2; CAPL; FSP1; MTS1; P9KA; PEL98	IHC-P, FC, ELISA	Human, Mouse, Rat
	S100A4 Antibody (YA3917) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to S100A4.

HY-P84220A

	S100A4 Antibody (YA3917)(PBS only) 42A; 18A2; CAPL; FSP1; MTS1; P9KA; PEL98	IHC-P, FC, ELISA	Human, Mouse, Rat
	S100A4 Antibody (YA3917) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to S100A4.

HY-P83337

	MRPS18B Antibody (YA3082) PTD017; S18Amt; C6orf14; HSPC183; MRPS18-2; HumanS18A; MRP-S18-2	WB, ICC/IF, IP	Human, Mouse, Rat
	MRPS18B Antibody (YA3082) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MRPS18B.

HY-P83337A

	MRPS18B Antibody (YA3082)(PBS only) PTD017; S18Amt; C6orf14; HSPC183; MRPS18-2; HumanS18A; MRP-S18-2	WB, ICC/IF, IP	Human, Mouse, Rat
	MRPS18B Antibody (YA3082) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MRPS18B.

HY-P87138

	VAChT/SLC18A3 Antibody (YA6831) AChR antibody; MGC12716 antibody; rVAT antibody; Slc18A3 antibody; Solute carrier family 18 (vesicular acetylcholine) member 3 antibody; Solute carrier family 18 (vesicular monoamine) member 3 antibody; Solute carrier family 18 member 3 antibody; VAChT antibody; VACHT_HUMAN antibody; Vesicular acetylcholine transporter antibody;	IHC-F	Mouse
	VAChT/SLC18A3 Antibody (YA6831) is a Rat -derived and non-conjugated monoclonal antibody, targeting to VAChT/SLC18A3.

HY-P85626

	S100A4 Antibody (YA5318) 18A2; 42A; calcium Placental protein; Calvasculin; CAPL; Fibroblast specific protein 1; Fibroblast specific protein; FSP1; Leukemia multidrug resistance associated protein; Malignant transformation suppression 1; Metastasin; MTS1; OTTHUMP00000015467; OTTHUMP00000015468; P9KA; PEL98; Placental calcium-binding protein; Protein Mts1; Protein S100 A4; Protein S100-A4; S100 calcium binding protein A4; calcium protein, calvasculin, metastasin, murine placental homolog; S100 calcium binding protein A4; S100 calcium-binding protein A4; S100a4; S10A4_HUMAN.	WB	Human
	S100A4 Antibody (YA5318) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to S100A4.

HY-P85626A

	S100A4 Antibody (YA5318)(PBS only) 18A2; 42A; calcium Placental protein; Calvasculin; CAPL; Fibroblast specific protein 1; Fibroblast specific protein; FSP1; Leukemia multidrug resistance associated protein; Malignant transformation suppression 1; Metastasin; MTS1; OTTHUMP00000015467; OTTHUMP00000015468; P9KA; PEL98; Placental calcium-binding protein; Protein Mts1; Protein S100 A4; Protein S100-A4; S100 calcium binding protein A4; calcium protein, calvasculin, metastasin, murine placental homolog; S100 calcium binding protein A4; S100 calcium-binding protein A4; S100a4; S10A4_HUMAN.	WB	Human
	S100A4 Antibody (YA5318) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to S100A4.

HY-P80317

	S100A4 Antibody (YA084) 18A2 antibody; 42A antibody; calcium Placental protein antibody; Calvasculin antibody; CAPL antibody; Fibroblast specific protein 1 (FSP1) antibody; Fibroblast specific protein 1 antibody; Fibroblast specific protein antibody; FSP1 antibody; Leukemia multidrug resistance associated protein antibody; Malignant transformation suppression 1 (MTS1) antibody; Malignant transformation suppression 1 antibody; Metastasin antibody; MTS1 antibody; OTTHUMP00000015467 antibody; OTTHUMP00000015468 antibody; P9KA antibody; PEL98 antibody; Placental calcium-binding protein antibody; Protein Mts1 antibody; Protein S100 A4 antibody; Protein S100-A4 antibody; S100 calcium binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog) antibody; S100 calcium binding protein A4 antibody; S100 calcium-binding protein A4 antibody; S100a4 antibody; S10A4_HUMAN antibody;	WB, ICC/IF, IHC-P, IP, FC	Human, Mouse
	S100A4 Antibody (YA084) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to S100A4.

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Cat. No.	Product Name		Classification

HY-R00352

*hsa-miR-18a-3p mimic*		MicroRNAs miRNA mimics
hsa-miR-18a-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-RS13043

SLC18A1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
SLC18A1 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC18A1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-R00353

*hsa-miR-18a-5p mimic*		MicroRNAs miRNA mimics
hsa-miR-18a-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R02722

*mmu-miR-18a-3p mimic*		MicroRNAs miRNA mimics
mmu-miR-18a-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R04263

*rno-miR-18a-3p mimic*		MicroRNAs miRNA mimics
rno-miR-18a-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-RI02722

*mmu-miR-18a-3p inhibitor*		MicroRNAs miRNA inhibitors
mmu-miR-18a-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI00352A

*hsa-miR-18a-3p antagomir*		MicroRNAs miRNA antagomirs
hsa-miR-18a-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI00352

*hsa-miR-18a-3p inhibitor*		MicroRNAs miRNA inhibitors
hsa-miR-18a-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI04263

*rno-miR-18a-3p inhibitor*		MicroRNAs miRNA inhibitors
rno-miR-18a-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI00353

*hsa-miR-18a-5p inhibitor*		MicroRNAs miRNA inhibitors
hsa-miR-18a-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-R04263A

*rno-miR-18a-3p agomir*		MicroRNAs miRNA agomirs
rno-miR-18a-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R00353A

*hsa-miR-18a-5p agomir*		MicroRNAs miRNA agomirs
hsa-miR-18a-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R00352A

*hsa-miR-18a-3p agomir*		MicroRNAs miRNA agomirs
hsa-miR-18a-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R02722A

*mmu-miR-18a-3p agomir*		MicroRNAs miRNA agomirs
mmu-miR-18a-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RS16612

Kif18a Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Kif18a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Kif18a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS12170

RPL18A Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
RPL18A Human Pre-designed siRNA Set A contains three designed siRNAs for RPL18A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS07267

KIF18A Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
KIF18A Human Pre-designed siRNA Set A contains three designed siRNAs for KIF18A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS08934

MYO18A Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
MYO18A Human Pre-designed siRNA Set A contains three designed siRNAs for MYO18A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS23047

Kif18a Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Kif18a Rat Pre-designed siRNA Set A contains three designed siRNAs for Kif18a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS00559

ALDH18A1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
ALDH18A1 Human Pre-designed siRNA Set A contains three designed siRNAs for ALDH18A1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS25590

Aldh18a1 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Aldh18a1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Aldh18a1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS13044

SLC18A2 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
SLC18A2 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC18A2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS18436

Col18a1 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Col18a1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Col18a1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS02968

COL18A1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
COL18A1 Human Pre-designed siRNA Set A contains three designed siRNAs for COL18A1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS22033

Slc18a3 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Slc18a3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Slc18a3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS22032

Slc18a2 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Slc18a2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Slc18a2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS13045

SLC18A3 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
SLC18A3 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC18A3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RI02722A

*mmu-miR-18a-3p antagomir*		MicroRNAs miRNA antagomirs
mmu-miR-18a-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI04263A

*rno-miR-18a-3p antagomir*		MicroRNAs miRNA antagomirs
rno-miR-18a-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI00353A

*hsa-miR-18a-5p antagomir*		MicroRNAs miRNA antagomirs
hsa-miR-18a-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RS28551

Slc18a3 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Slc18a3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Slc18a3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS19101

Aldh18a1 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Aldh18a1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Aldh18a1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS28550

Slc18a2 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Slc18a2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Slc18a2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS24918

Col18a1 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Col18a1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Col18a1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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