371 Results for "

3-Hydroxy-

" in MedChemExpress (MCE) Product Catalog:
Products (371)

371 Results for "3-Hydroxy-" in MCE Product Catalog:

73
73 Publications Verification
Art. -Nr.: HY-17379
CAS. Nr.: 134523-03-8
Synonyms: CI-981; Atorvastatin hemicalcium
Atorvastatin hemicalcium salt (CI-981) is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, with blood-brain barrier permeability. Atorvastatin hemicalcium salt has the ability to effectively decrease blood lipids. Atorvastatin hemicalcium salt inhibits human SV-SMC proliferation and invasion with IC50s of 0.39 μM and 2.39 μM, respectively [3] .
loading...
    loading...
17
17 Cited Publications
Art. -Nr.: HY-17365
CAS. Nr.: 79517-01-4
Synonyms: SMS 201-995 acetate
Octreotide acetate, a long-acting synthetic analog of native somatostatin, inhibits growth hormone, glucagon, and insulin more potently.
loading...
    loading...
7
7 Cited Publications
Art. -Nr.: HY-100793
CAS. Nr.: 126411-39-0
Reinheit:  99.80%
Synonyms: GW 485801
SR12813 (GW 485801) is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, with an IC50 value of 0.85 μM . SR12813 is also an efficient agonist of human pregnane X receptor (hPXR). SR12813 can strongly bind to hPXR but not to mouse PXR (mPXR) [3].
loading...
    loading...
3
3 Cited Publications
Art. -Nr.: HY-N0761
CAS. Nr.: 537-73-5
Synonyms: 3-Hydroxy-4-methoxycinnamic acid
Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) is an orally active cinnamic acid derivative. Isoferulic acid exhibits hypoglycemic, antiviral, and antioxidant activities. Isoferulic acid can also inhibit fructose- and glucose-mediated protein glycation. Isoferulic acid can be used in the research of diseases such as diabetes [3] .
loading...
    loading...
2
2 Cited Publications
Art. -Nr.: HY-113294
CAS. Nr.: 484-78-6
Reinheit:  99.90%
Synonyms: 3-Hydroxy-DL-kynurenine
3-Hydroxykynurenine, a metabolite of tryptophan, is a potential endogenous neurotoxin whose increased levels have been described in several neurodegenerative disorders. 3-Hydroxykynurenine induces neuronal apoptosis .
loading...
    loading...
2
2 Cited Publications
Art. -Nr.: HY-P72228
Reinheit:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HMGCR; 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase; 3-Hydroxy-3-Methylglutaryl-CoA Reductase; Hydroxymethylglutaryl-CoA Reductase (NADPH); 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase; Alternative Protein HMGCR; HMG-CoA Reductase; LGMDR28; 3-Hydrox
Species:  
Human
Source:  
E. coli
loading...
    loading...
1
1 Cited Publications
Art. -Nr.: HY-I0637
CAS. Nr.: 621-59-0
Synonyms: 3-Hydroxy-4-methoxybenzaldehyde
Isovanillin is an aldehyde oxidase inhibitor . Antispasmodic activities . Antidiarrheal activities [3].
loading...
    loading...
1
1 Cited Publications
Art. -Nr.: HY-W008467
CAS. Nr.: 16820-18-1
Forschungsgebiete:  

Others

(S)-2-amino-3-hydroxy-2-methylpropanoic acid is a serine derivative .
loading...
    loading...
1
1 Cited Publications
Art. -Nr.: HY-103228
CAS. Nr.: 143692-48-2
Reinheit:  98.37%
Synonyms: LY300168 hydrochloride
Target:  

iGluR

Forschungsgebiete:  

Neurological Disease

GYKI 53655 (LY300168) hydrochloride is an α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) antagonist.
loading...
    loading...
1
1 Cited Publications
Art. -Nr.: HY-P81197
Synonyms: 3 Hydroxy 3 methylglutaryl CoA reductase antibody; 3 Hydroxy 3 methylglutaryl Coenzyme A reductase antibody; 3 Hydroxymethylglutaryl CoA reductase antibody; 3-Hydroxy-3-methylglutaryl CoA reductase (NADPH) antibody; 3-Hydroxy-3-methylglutaryl-coenzyme A reductase antibody; 3H3M antibody; HMDH_HUMAN antibody; HMG CoA reductase antibody; HMG CoAR antibody; HMG-CoA reductase antibody; Hmgcr antibody; Hydroxymethylglutaryl CoA reductase antibody; LDLCQ3 antibody; MGC103269 antibody; Red antibody;

Host:  

Rabbit

Application:  

WB, IP

Reactivity:  

Human, Mouse, Rat

loading...
    loading...
1
1 Cited Publications
Art. -Nr.: HY-15079
CAS. Nr.: 161832-65-1
Reinheit:  99.77%
Synonyms: GYKI-53773; LY-300164
Target:  

iGluR Apoptosis

Forschungsgebiete:  

Neurological Disease Cancer

Talampanel (LY300164) is an orally and selective α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptor antagonis with anti-seizure activity . Talampanel (IVAX) has neuroprotective effects in rodent stroke models . Talampanel attenuates caspase-3 dependent apoptosis in mouse brain .
loading...
    loading...
1
1 Cited Publications
Art. -Nr.: HY-105055
CAS. Nr.: 77327-05-0
Reinheit:  99.95%
Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. Didemnin B can be used for the research of cancer .
loading...
    loading...
1
1 Cited Publications
Art. -Nr.: HY-N0468
CAS. Nr.: 63279-13-0
Rebaudioside D is an orally active sweetener that targets and activates FXR, modulates Acetyl-CoA Carboxylase, and inhibits 3-hydroxy-3-methylglutaryl-CoA reductase. Rebaudioside D regulates bile acid homeostasis and lipid metabolism, reduces the synthesis rates of fatty acids and cholesterol, and exerts multiple effects including anti-adipogenesis, hepatoprotection, anti-steatosis, gut microbiota modulation, enhancement of secondary bile acid metabolism, anti-endotoxin activity, regulation of bile acid transport, and inhibition of bile acid efflux. Rebaudioside D also reduces body weight gain, visceral fat accumulation, hepatic triglyceride and cholesterol accumulation, hepatic lipid peroxidation, and decreases the circulating level of lipopolysaccharide-binding protein. Rebaudioside D additionally enhances the secondary bile acid metabolic pathway of intestinal bacteria, upregulates the gene expression of ileal organic solute transporter α, and downregulates the gene expression of hepatic bile salt export pump. Rebaudioside D does not affect glucose homeostasis, alter total caloric intake or fecal energy excretion, induce weight gain, exacerbate obesity, promote hepatic steatosis, impair brown adipose tissue function, nor change skeletal muscle metabolism-related proteins. Rebaudioside D can be used in diet-induced obesity and obesity-related research .
loading...
    loading...
Art. -Nr.: HY-N6864
CAS. Nr.: 645-08-9
Synonyms: 3-Hydroxy-4-methoxybenzoic acid
Isovanillic acid (3-Hydroxy-4-methoxybenzoic acid) is a phenolic acid isolated from isolated from Scrophularia ningpoensis, with anti-thrombotic activity [3].
loading...
    loading...
Art. -Nr.: HY-W002339
CAS. Nr.: 1121-25-1
3-Hydroxy-2-methylpyridine is a pharmaceutical intermediate that can be used in the synthesis of pyrimidines. 3-Hydroxy-2-methylpyridine acts as a corrosion inhibitor, serving as a mixed-type corrosion inhibitor for carbon steel in HCl medium .
loading...
    loading...
Art. -Nr.: HY-108263
CAS. Nr.: 179237-49-1
Reinheit:  97.02%
Synonyms: CGP52421
Target:  

FLT3

Forschungsgebiete:  

Cancer

3-Hydroxy Midostaurin (CGP 52421), a metabolite of PKC412, effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC50s of approximately 132 nM and 9.8 μM in culture medium and plasma, respectively. 3-Hydroxy Midostaurin is less selective but more cytotoxic than PKC412 .
loading...
    loading...
Art. -Nr.: HY-W342499
CAS. Nr.: 55682-83-2
Synonyms: Methyl 3-Hydroxytetradecanoate; 3-OH PAME; Methyl 3-Hydroxymyristate
Target:  

Fungal

Forschungsgebiete:  

Metabolic Disease

3-Hydroxy myristic acid methyl ester (Methyl 3-hydroxytetradecanoate) is the quorum-sensing signal molecule (quormone), which regulates the virulence of Ralstonia solanacearum .
loading...
    loading...
Art. -Nr.: HY-133111S
CAS. Nr.: 1079774-23-4
Reinheit:  99.92%
3-Hydroxy agomelatine-d3 is a deuterium labeled 3-Hydroxy agomelatine. 3-Hydroxy agomelatine is a 5-HT2C receptor antagonist with an IC50 of 3.2 μM and a Ki of 1.8 μM .
loading...
    loading...
Art. -Nr.: HY-141639
CAS. Nr.: 40165-89-7
Target:  

Drug Derivative

Forschungsgebiete:  

Inflammation/Immunology

3-Hydroxyheptadecanoic acid is a type of 3-hydroxy acid that can be used as a chemical marker for endotoxins .
loading...
    loading...
Art. -Nr.: HY-117201
CAS. Nr.: 7367-87-5
Synonyms: 3-Hydroxy octanoic acid methyl ester
Forschungsgebiete:  

Others

Methyl 3-hydroxyoctanoate (3-Hydroxy octanoic acid methyl ester) is an ester. Methyl 3-hydroxyoctanoate can be isolated from Pineapple .
loading...
    loading...