377 Results for "

A4

" in MedChemExpress (MCE) Product Catalog:
Products (377)

377 Results for "A4" in MCE Product Catalog:

17
17 Publications Verification
Cat. No.: HY-15858
CAS No.: 1177827-73-4
Purity:  99.87%
Synonyms: ENOblock
Target:  

Enolase Apoptosis

Research Areas:  

Metabolic Disease Cancer

AP-III-a4 (ENOblock) is a nonsubstrate analogue enolase inhibitor with an IC50 of 0.576 uM. AP-III-a4 can be used for the research of cancer and diabetic .
loading...
    loading...
17
17 Publications Verification
Cat. No.: HY-15858A
CAS No.: 2070014-95-6
Purity:  99.24%
Synonyms: ENOblock hydrochloride
Target:  

Enolase Apoptosis

Research Areas:  

Metabolic Disease Cancer

AP-III-a4 (ENOblock) hydrochloride is a nonsubstrate analogue enolase inhibitor with an IC50 of 0.576 uM. AP-III-a4 hydrochloride can be used for the research of cancer and diabetic .
loading...
    loading...
12
12 Cited Publications
Cat. No.: HY-B0134
CAS No.: 58970-76-6
Synonyms: Ubenimex
Bestatin is a natural, broad-spectrum, and competitive CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase inhibitor. Bestatin has anticancer effects .
loading...
    loading...
12
12 Cited Publications
Cat. No.: HY-B0134A
CAS No.: 65391-42-6
Synonyms: Ubenimex hydrochloride
Bestatin hydrochloride is an inhibitor of CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase, used for cancer research.
loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-N2146
CAS No.: 117048-59-6
Synonyms: CRC 87-09
Combretastatin A4 is a microtubule-targeting agent that binds β-tubulin with Kd of 0.4 μM.
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-P71140
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Protein S100-A4; Calvasculin; Metastasin; Placental calcium-binding protein; Protein Mts1; S100 calcium-binding protein A4; S100A4; CAPL; MTS1
Species:  
Source:  
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-103226
CAS No.: 423169-68-0
Purity:  99.93%
Target:  

Aminopeptidase

Research Areas:  

Inflammation/Immunology

SC-57461A is a potent, orally active, nonpeptide, and selective inhibitor of Leukotriene A4 (LTA4) hydrolase with IC50s of 2.5 nM, 3 nM, and 23 nM for recombinant human, mouse, and rat LTA4 hydrolase, respectively .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P71084
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Protein S100-A4; Metastasin; Metastatic cell protein; PEL98; Placental calcium-binding protein; Protein 18A2; Protein Mts1; S100 calcium-binding protein A4; S100A4; Capl; Mts1
Species:  
Source:  
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-166648
DSPE-PEG2000-Maleimide sodium (purity>98%) is a functional lipid component and a thiol-reactive crosslinker. DSPE-PEG2000-Maleimide sodium (purity>98%) undergoes Michael addition with the thiol groups of thiolated or cyclic RGD peptides to form stable thioether bonds and DSPE-PEG2000-RGD. DSPE-PEG2000-Maleimide sodium (purity>98%) is applicable to research on drug delivery .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-166648A
Target:  

Liposome

Research Areas:  

Others

DSPE-PEG-Maleimide ammonium (MW 2000) is a functional lipid component and a thiol-reactive crosslinker. DSPE-PEG-Maleimide ammonium (MW 2000) undergoes Michael addition with the thiol groups of thiolated or cyclic RGD peptides to form stable thioether bonds and DSPE-PEG (2000)-RGD. DSPE-PEG-Maleimide ammonium (MW 2000) is applicable to research on drug delivery .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P990173

Target:  

PD-1/PD-L1

Research Areas:  

Cancer

Anti-Mouse/Rat/Human PD-L1 Antibody (368A.4H1) is a mouse-derived PD-L1 IgG1 κ type antibody inhibitor. Anti-Mouse/Rat/Human PD-L1 Antibody (368A.4H1) increases IFN-γ levels in organoid-primed T cells. Anti-Mouse/Rat/Human PD-L1 Antibody (368A.4H1) can be used for the researches of cancer, such as oral squamous cell carcinoma and mammary cancer .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P70577
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Alpha-Synuclein; Non-A Beta Component of AD Amyloid; Non-A4 Component of Amyloid Precursor; NACP; SNCA; NACP; PARK1
Species:  
Source:  
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-113509
CAS No.: 89663-86-5
Purity:  98.0%
Synonyms: LXA4
Lipoxin A4 (LXA4), an endogenous lipoxygenase-derived eicosanoid mediator, has potent dual pro-resolving and anti-inflammatory properties . Lipoxin A4 inhibits proliferation and inflammatory cytokine/chemokine production of human epidermal keratinocytes (NHEKs) associated with the ERK1/2 and NF-kB pathways . Lipoxin A4 inhibits serum amyloid A (SAA)-mediated IL-8 release with an IC50 value of 25.74 nM .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-17625
CAS No.: 943764-99-6
Synonyms: CTX-4430
Target:  

Aminopeptidase

Research Areas:  

Inflammation/Immunology

Acebilustat (CTX-4430) is a leukotriene A4 hydrolase inhibitor, used for an oral antiinflammatory agent.
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-100450
CAS No.: 78606-80-1
Purity:  ≥98.0%
BML-111, a lipoxin A4 analog, is a lipoxin A4 receptor agonist. BML-111 represses the activity of angiotensin converting enzyme (ACE) and increases the activity of angiotensinconverting enzyme 2 (ACE2). BML-111 has antiangiogenic, antitumor and anti-inflammatory properties .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-10825
CAS No.: 929915-58-2
Purity:  99.86%
Target:  

Aminopeptidase

Research Areas:  

Metabolic Disease

DG051 is a potent leukotriene A4 hydrolase inhibitor of leukotriene B4 biosynthesis in the enzyme assay with an IC50=47 nM.
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-125770
CAS No.: 71774-08-8
Purity:  ≥98.0%
5(S)-HPETE is a 5-lipoxygenase substrate and Arachidonic acid (HY-109590) metabolite. 5(S)-HPETE forms via 5-LOX-catalyzed hydroperoxidation of arachidonic acid. 5(S)-HPETE undergoes 5-LOX-catalyzed epoxidation (dehydration) to form leukotriene A4. 5(S)-HPETE can be used for the research of asthma, rheumatoid arthritis .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P704352
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Amyloid-beta precursor protein; APP; CVAP; PN-II; PreA4; A4; AD1
Species:  
Source:  
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P71143
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Kallistatin; Kallikrein Inhibitor; Peptidase Inhibitor 4; PI-4; Serpin A4; SERPINA4; KST; PI4
Species:  
Source:  
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-B0778
CAS No.: 129496-10-2
Milbemycin oxime is an orally active macrolide with broad-spectrum antiparasitic activity. Milbemycin oxime is a mixture of oximes consisting of oxime derivatives corresponding to milbemycin A4 and A3. Milbemycin oxime binds to glutamate-gated chloride channels and has inhibitory potency against intestinal nematodes and lung/heart worms .
loading...
    loading...