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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
23 Results for "
ACAT2
" in MedChemExpress (MCE) Product Catalog:
Products (23)
23 Results for "ACAT2" in MCE Product Catalog:
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20 Publications Verification
Synonyms: CI-1011; PD-148515
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Research Areas:
Avasimibe (CI-1011; PD-148515) is an orally active acyl coenzyme A-cholesterol acyltransferase (ACAT; also called SOAT)) inhibitor with IC50s of 24 and 9.2 µM for ACAT1 and ACAT2, respectively . Avasimibe can be used for the research of prostate cancer [2].
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Nevanimibe (PD-132301) is an orally active and selective acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM. Nevanimibe inhibits ACAT2 with an EC50 of 368 nM. Nevanimibe induces cell apoptosis and has the potential for adrenocortical cancer .
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4 Cited Publications
Synonyms: PD-132301 hydrochloride; ATR101 hydrochloride
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Research Areas:
Nevanimibe hydrochloride (PD-132301 hydrochloride) is an orally active and selective acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM. Nevanimibe hydrochloride inhibits ACAT2 with an EC50 of 368 nM. Nevanimibe hydrochloride induces cell apoptosis and has the potential for adrenocortical cancer .
1
1 Cited Publications
Category:
Cardiovascular Disease Microorganisms Terpenoids Sesquiterpenes Disease Research Fields Inflammation/Immunology
Target:
Cat. No.: HY-N0466
CAS No.: 58543-16-1
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Cat. No.: HY-RS00139
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ACAT2 Human Pre-designed siRNA Set A contains three designed siRNAs for ACAT2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS00140
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Acat2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Acat2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS00141
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ACAT2 Rat Pre-designed siRNA Set A contains three designed siRNAs for ACAT2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-13215R
CAS No.: 166518-60-1
Synonyms: CI-1011 (Standard); PD-148515 (Standard)
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Research Areas:
Avasimibe (Standard) is the analytical standard of Avasimibe. This product is intended for research and analytical applications. Avasimibe (CI-1011; PD-148515) is an orally active acyl coenzyme A-cholesterol acyltransferase (ACAT; also called SOAT)) inhibitor with IC50s of 24 and 9.2 µM for ACAT1 and ACAT2, respectively . Avasimibe can be used for the research of prostate cancer [2].
Cat. No.: HY-N14614
CAS No.: 151519-44-7
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Cat. No.: HY-106938
CAS No.: 141993-70-6
Synonyms: WAY-ACA 147
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Research Areas:
Eldacimibe is an ACAT2 inhibitor. Eldacimibe can lower plasma cholesterol levels by blocking cholesterol absorption and can prevent macrophages from turning into foam cells. Eldacimibe can be used in the study of cardiovascular diseases (atherosclerosis), endocrine and metabolic diseases (hypercholesterolemia) .
Cat. No.: HY-100399AR
CAS No.: 133825-81-7
Synonyms: PD-132301 hydrochloride (Standard); ATR101 hydrochloride (Standard)
Research Areas:
Nevanimibe hydrochloride (Standard) is the analytical standard of Nevanimibe hydrochloride. This product is intended for research and analytical applications. Nevanimibe hydrochloride (PD-132301 hydrochloride) is an orally active and selective acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM. Nevanimibe hydrochloride inhibits ACAT2 with an EC50 of 368 nM. Nevanimibe hydrochloride induces cell apoptosis and has the potential for adrenocortical cancer .
Cat. No.: HY-P701332
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Acetyl-CoA acetyltransferase cytosolic; Acetyl-CoA transferase-like protein; Cytosolic acetoacetyl-CoA thiolase; ACTL; ACAT2
Cat. No.: HY-P88953A
Synonyms: ACACT2; ACAT2; ARGP2
Cat. No.: HY-RS19037
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Soat2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Soat2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS13550
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Research Areas:
SOAT2 Human Pre-designed siRNA Set A contains three designed siRNAs for SOAT2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
