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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
AEP
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "AEP" in MCE Product Catalog:
3
3 Cited Publications
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P70897A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LGMN; LGMN1; Prev. PRSC1; AEP; Asparaginyl Endopeptidase; Cysteine Protease 1; Protease, Cysteine 1; Legumain; Protease, Cysteine, 1 (Legumain)
Species:
Human
Source:
HEK293
Target:
Research Areas:
AEP-IN-2 is an asparagine endopeptidase (AEP) inhibitor via block AEP cleavage of APP and Tau. AEP-IN-2 has oral activity and decreases Aβ40 and Aβ42 and p-Tau levels .
Cat. No.: HY-162076
CAS No.: 2978521-26-3
Target:
Research Areas:
AEP-IN-3 (compound 18) is an orally active, potent and brain penetrant asparagine endopeptidase (AEP) inhibitor, with an IC50 of 7.8 ± 0.9 nM. AEP-IN-3 can be used for Alzheimer’s Disease (AD) research .
Cat. No.: HY-E70421
Target:
Research Areas:
Peptide ligase is an Asx-specific asparaginyl endopeptidase (AEP) ligase and cyclase that can be isolated from the pods of butterfly pea (Clitoria ternatea). Peptide ligase mediates traceless intramolecular cyclization of polypeptides. Peptide ligase mediates intermolecular ligation of polypeptides or proteins. Peptide ligase can be used to cyclize food-derived angiotensin-converting enzyme (ACE) inhibitory peptides, thereby enhancing the stability and biological activity of ACE inhibitory peptides. Peptide ligase is applicable to relevant research in the fields of food and biopharmaceuticals .
Cat. No.: HY-146068
CAS No.: 3032742-75-6
Target:
Research Areas:
AEP-IN-1 (Compound 13e) is a CNS agent-like non-covalent inhibitor of asparagine endopeptidase (AEP), with the IC50 of 89 nM. AEP-IN-1 can be used for the research of numerous neurological diseases such as Alzheimer’s disease (AD) .
Cat. No.: HY-133570
CAS No.: 75747-23-8
Target:
Research Areas:
17-AEP-GA, an HSP90 antagonist, is a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion. ADCs Toxin .
Cat. No.: HY-153189
CAS No.: 1609067-49-3
Target:
Research Areas:
TrkB agonist-1 is an orally active, blood-brain barrier-permeable TrkB agonist. TrkB agonist-1 activates the TrkB signaling pathway and its downstream AKT and ERK/MAPK pathways via its released parent compound, reduces AEP enzyme activity and inhibits its activation, and simultaneously suppresses the production of pro-inflammatory cytokines. TrkB agonist-1 is used in the research of Alzheimer's disease .
Cat. No.: HY-RS07617
Target:
Research Areas:
LGMN Human Pre-designed siRNA Set A contains three designed siRNAs for LGMN gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P703851
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: LGMN; LGMN1; Prev. PRSC1; AEP; Asparaginyl Endopeptidase; Cysteine Protease 1; Protease, Cysteine 1; Legumain; Protease, Cysteine, 1 (Legumain)
Species:
Human
Source:
HEK293
Cat. No.: HY-RS17268
Target:
Research Areas:
Lgmn Mouse Pre-designed siRNA Set A contains three designed siRNAs for Lgmn gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Category:
Target:
Cat. No.: HY-P70216A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LGMN; LGMN1; Prev. PRSC1; AEP; Asparaginyl Endopeptidase; Cysteine Protease 1; Protease, Cysteine 1; Legumain; Protease, Cysteine, 1 (Legumain)
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P701968
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PRIM1; Primase Polypeptide 1, 49kDa; DNA Primase Subunit 1; DNA Primase Subunit 48; Primase, DNA, Polypeptide 1 (49kDa); Primase P49 Subunit; DNA Primase 49 KDa Subunit; DNA Primase AEP; DNA Primase Small Subunit; DNA Primase 1; Primase (DNA) Subunit 1; D
Species:
Human
Source:
E. coli
Cat. No.: HY-P701969
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PRIM1; Primase Polypeptide 1, 49kDa; DNA Primase Subunit 1; DNA Primase Subunit 48; Primase, DNA, Polypeptide 1 (49kDa); Primase P49 Subunit; DNA Primase 49 KDa Subunit; DNA Primase AEP; DNA Primase Small Subunit; DNA Primase 1; Primase (DNA) Subunit 1; D
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
