19 Results for "

Alisol A

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "Alisol A" in MCE Product Catalog:

5
Alisol A
Alisol A
0 Images
5 Cited Publications
Cat. No.: HY-N0853
CAS No.: 19885-10-0
Category:  

Triterpenes Alisma plantago-aquatica Linn. Terpenoids Other Diseases Plants Alismataceae Disease Research Fields

Target:  

AMPK Acetyl-CoA Carboxylase PPAR MMP Interleukin Related

Alisol A is an orally active tetracyclic triterpenoid compound of the prototerpane type. Alisol A can be extracted from the rhizome of Alisma orientale. Alisol A activates AMPK/ACC/SREBP-1c, SIRT1, PPARα, inhibits MMP-2/-9, decreases inflammatory cytokine expression (IL-1β, IL-6, IL-8). Alisol A has anti-tumor activity against breast cancer and colorectal cancer. Alisol A has anti-obesity and anti-atherosclerotic activities. Alisol A can be used in the research of hepatitis B, breast cancer, colorectal cancer, atherosclerosis, and obesity .
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Alisol B 23-acetate
Alisol B 23-acetate
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3 Cited Publications
Cat. No.: HY-N0805
CAS No.: 26575-95-1
Synonyms: 23-Acetylalismol B; 23-O-AcetylAlisol B; Alisol B monoacetate
Category:  

Triterpenes Alisma plantago-aquatica Linn. Terpenoids Other Diseases Plants Alismataceae Disease Research Fields

Target:  

Apoptosis Reactive Oxygen Species (ROS) CDK MMP PARP FXR Syk

Alisol B 23-acetate is an orally active prototerpane-type triterpenoid. Alisol B 23-acetate can be isolated from Alisma orientalis. Alisol B 23-acetate induces Apoptosis, promotes ROS generation, downregulates CDK4/6, MMP-2/9, upregulates cleaved PARP, activates FXR and inhibits Syk. Alisol B 23-acetate has anti-inflammatory and hepatoprotective activities. Alisol B 23-acetate protects the kidney from ischemia-reperfusion injury. Alisol B 23-acetate has anticancer activity against ovarian cancer, colon cancer, lung cancer, and gastric cancer. Alisol B 23-acetate can be used in the study of atherosclerosis and allergic asthma .
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1
Alisol B
Alisol B
0 Images
1 Cited Publications
Cat. No.: HY-N0805A
CAS No.: 18649-93-9
Category:  

Triterpenes Alisma plantago-aquatica Linn. Terpenoids Metabolic Disease Plants Alismataceae Disease Research Fields

Target:  

Epoxide Hydrolase CaMK Autophagy Apoptosis

Alisol B is a triterpene with diverse biological activities. Alisol B binds human soluble epoxide hydrolase (sEH) with a Ki of 5.97 μM and reduces sEH activity. Alisol B inhibits RANKL-induced JNK phosphorylation, NFATc1 and c-Fos expression, osteoclast formation, mature osteoclast pit-forming and actin ring activity, and SERCA pump activity. Alisol B induces calcium mobilization, CaMKK-AMPK-mTOR pathway activation, autophagic flux, autophagosome formation, G1 phase cell cycle arrest, endoplasmic reticulum stress, unfolded protein responses, and cancer cell apoptosis. Alisol B can be used for the research of hypercalcemia, osteoporosis, rheumatoid arthritis, periodontitis, acute kidney injury, and breast cancer .
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1
Alisol A 24-acetate
Alisol A 24-acetate
0 Images
1 Cited Publications
Cat. No.: HY-N0853A
CAS No.: 18674-16-3
Synonyms: Alisol A 24-monoacetate; Alisol A monoacetate
Category:  

Triterpenes Alisma plantago-aquatica Linn. Terpenoids Other Diseases Plants Alismataceae Disease Research Fields

Target:  

AMPK Carnitine Palmitoyltransferase (CPT) Acyltransferase Fatty Acid Synthase (FASN) Acetyl-CoA Carboxylase Bcl-2 Family PPAR Nuclear Factor of activated T Cells (NFAT) PI3K Akt PKA ERK Apoptosis Autophagy

Alisol A 24-acetate (Alisol A monoacetate) is an orally active derivative of protostane-type tetracyclic triterpenoid. Alisol A 24-acetate upregulates the expression of adiponectin, AMPKα, CPT1, and ACOX1; downregulates the expression of SREBP-1c, ACC, FAS, Bcl-2, Bcl-xl, PPAR-γ, perilipin A, and NFATc1; inhibits the activity of PI3K/Akt/mTOR and HMGR; and activates the PKA and ERK signaling pathways. Alisol A 24-acetate regulates cell apoptosis (apoptosis), autophagy (Autophagy, hepatic lipid accumulation, inflammatory response, neuroprotection, MRSA membrane integrity, and osteoclast differentiation. Alisol A 24-acetate can be used in research related to non-alcoholic fatty liver disease, nephrotoxicity, obesity, global cerebral ischemia-reperfusion injury, bacterial infection, and osteoporosis .
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1
5-Methyltetrahydrofolic acid (Standard)
5-Methyltetrahydrofolic acid (Standard)
0 Images
1 Cited Publications
Cat. No.: HY-113046R
CAS No.: 134-35-0
Synonyms: 5-Methyl THF (Standard); 5-MTHF (Standard)
Category:  

Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite

Target:  

Reference Standards Endogenous Metabolite

Alisol C 23-acetate (Standard) is the analytical standard of Alisol C 23-acetate. This product is intended for research and analytical applications. Alisol C 23-acetate is a natural product extracted from Alisma orientale, which can significantly reduce delayed-type hypersensitivity reactions.
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Alisol F
Alisol F
0 Images
1 Cited Publications
Cat. No.: HY-N0854
CAS No.: 155521-45-2
Category:  

Infection Triterpenes Terpenoids Alisma orinentale (Samuel.) Juz. Plants Alismataceae Disease Research Fields

Target:  

HBV ERK JNK p38 MAPK STAT NF-κB TNF Receptor Interleukin Related NO Synthase COX

Alisol F is a protostane-type triterpenoid with anti-inflammatory and anti-hepatitis B virus activities. Alisol F inhibits LPS (HY-D1056)-induced phosphorylation of ERK, JNK, p38, STAT3 and NF-κB (p65), suppresses the production of NO, IL-6, TNF-α and IL-1β, and also downregulates the levels of iNOS and COX-2. Alisol F reduces the serum alanine aminotransferase and aspartate aminotransferase levels in mice with acute liver injury and ameliorates their liver pathological damage .
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Alisol C
Alisol C
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Cat. No.: HY-N6570
CAS No.: 30489-27-1
Category:  

Triterpenes Terpenoids Alisma orinentale (Samuel.) Juz. Plants Alismataceae

Target:  

Others

Alisol C is a triterpenoid that can be found in the tuber of Alisma orientale (Sam.) Juzep .
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Alisol C 23-acetate
Alisol C 23-acetate
0 Images
Cat. No.: HY-N0856
CAS No.: 26575-93-9
Synonyms: 23-O-AcetylAlisol C; Alisol C monoacetate
Category:  

Cardiovascular Disease Triterpenes Alisma plantago-aquatica Linn. Terpenoids Alisma orinentale (Samuel.) Juz. Plants Alismataceae Disease Research Fields

Target:  

Others

Alisol C 23-acetate, a natural product extracted from Alisma orinentale, can significantly and strongly inhibit DTH response after oral administration.
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Alisol G
Alisol G
0 Images
Cat. No.: HY-N0855
CAS No.: 155521-46-3
Synonyms: Alisol-G; 25-AnhydroAlisol A
Category:  

Triterpenes Alisma plantago-aquatica Linn. Terpenoids Other Diseases Plants Alismataceae Disease Research Fields

Target:  

Carboxylesterase (CES) Bacterial HBV

Alisol G (25-Anhydroalisol A) is a human carboxylesterase 2 (hCES2) inhibitor with an IC50 of 3.85 μM. Alisol G exhibits cytotoxic activity against human cancer cells, antibacterial activity against Gram-positive strains, and anti-hepatitis B virus activity. Alisol G can be used in research related to lung cancer, breast cancer, prostate cancer, bacterial infections, and HBV infections .
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Alisol A 24-acetate (Standard)
Alisol A 24-acetate (Standard)
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Cat. No.: HY-N0853AR
CAS No.: 18674-16-3
Synonyms: Alisol A 24-monoacetate (Standard); Alisol A monoacetate (Standard)
Category:  

Triterpenes Alisma plantago-aquatica Linn. Terpenoids Plants Alismataceae

Target:  

Reference Standards Others

Alisol A 24-acetate (Standard) is the analytical standard of Alisol A 24-acetate. This product is intended for research and analytical applications.
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Alisol A (Standard)
Alisol A (Standard)
0 Images
Cat. No.: HY-N0853R
CAS No.: 19885-10-0
Category:  

Triterpenes Alisma plantago-aquatica Linn. Terpenoids Plants Alismataceae

Target:  

Reference Standards AMPK Acetyl-CoA Carboxylase PPAR MMP Interleukin Related

Alisol A (Standard) is the analytical standard of Alisol A (HY-N0853). This product is intended for research and analytical applications. Alisol A is an orally active tetracyclic triterpenoid compound of the prototerpane type. Alisol A can be extracted from the rhizome of Alisma orientale. Alisol A activates AMPK/ACC/SREBP-1c, SIRT1, PPARα, inhibits MMP-2/-9, decreases inflammatory cytokine expression (IL-1β, IL-6, IL-8). Alisol A has anti-tumor activity against breast cancer and colorectal cancer. Alisol A has anti-obesity and anti-atherosclerotic activities. Alisol A can be used in the research of hepatitis B, breast cancer, colorectal cancer, atherosclerosis, and obesity .
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Alisol A 23-acetate
Alisol A 23-acetate
0 Images
Cat. No.: HY-129162
CAS No.: 19865-75-9
Category:  

Triterpenes Alisma plantago-aquatica Linn. Terpenoids Plants Alismataceae

Target:  

Others

Alisol A 23-acetate is a natural product that can be isolated from Rhizoma Alismatis .
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Alisol B 23-acetate (Standard)
Alisol B 23-acetate (Standard)
0 Images
Cat. No.: HY-N0805R
CAS No.: 26575-95-1
Synonyms: 23-Acetylalismol B (Standard); 23-O-AcetylAlisol B (Standard); Alisol B monoacetate (Standard)
Category:  

Triterpenes Alisma plantago-aquatica Linn. Terpenoids Plants Alismataceae

Target:  

Reference Standards Apoptosis Reactive Oxygen Species (ROS) CDK MMP PARP FXR Syk

Alisol B 23-acetate (Standard) is the analytical standard of Alisol B 23-acetate (HY-N0805). This product is intended for research and analytical applications. Alisol B 23-acetate is an orally active prototerpane-type triterpenoid. Alisol B 23-acetate can be isolated from Alisma orientalis. Alisol B 23-acetate induces Apoptosis, promotes ROS generation, downregulates CDK4/6, MMP-2/9, upregulates cleaved PARP, activates FXR and inhibits Syk. Alisol B 23-acetate has anti-inflammatory and hepatoprotective activities. Alisol B 23-acetate protects the kidney from ischemia-reperfusion injury. Alisol B 23-acetate has anticancer activity against ovarian cancer, colon cancer, lung cancer, and gastric cancer. Alisol B 23-acetate can be used in the study of atherosclerosis and allergic asthma .
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Alisol C 23-acetate (Standard)
Alisol C 23-acetate (Standard)
0 Images
Cat. No.: HY-N0856R
CAS No.: 26575-93-9
Synonyms: 23-O-AcetylAlisol C (Standard); Alisol C monoacetate (Standard)
Category:  

Triterpenes Alisma plantago-aquatica Linn. Terpenoids Alisma orinentale (Samuel.) Juz. Plants Alismataceae

Target:  

Reference Standards Others

Alisol C 23-acetate (Standard) is the analytical standard of Alisol C 23-acetate. This product is intended for research and analytical applications. Alisol C 23-acetate is a natural product extracted from Alisma orientale, which can significantly reduce delayed-type hypersensitivity reactions.
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Alisol B (Standard)
Alisol B (Standard)
0 Images
Cat. No.: HY-N0805AR
CAS No.: 18649-93-9
Category:  

Triterpenes Alisma plantago-aquatica Linn. Terpenoids Plants Alismataceae

Target:  

Reference Standards Epoxide Hydrolase CaMK Autophagy Apoptosis

Alisol B (Standard) is the analytical standard of Alisol B (HY-N0805A). This product is intended for research and analytical applications. Alisol B is a triterpene with diverse biological activities. Alisol B binds human soluble epoxide hydrolase (sEH) with a Ki of 5.97 μM and reduces sEH activity. Alisol B inhibits RANKL-induced JNK phosphorylation, NFATc1 and c-Fos expression, osteoclast formation, mature osteoclast pit-forming and actin ring activity, and SERCA pump activity. Alisol B induces calcium mobilization, CaMKK-AMPK-mTOR pathway activation, autophagic flux, autophagosome formation, G1 phase cell cycle arrest, endoplasmic reticulum stress, unfolded protein responses, and cancer cell apoptosis. Alisol B can be used for the research of hypercalcemia, osteoporosis, rheumatoid arthritis, periodontitis, acute kidney injury, and breast cancer.
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Alisol F 24-acetate
Alisol F 24-acetate
0 Images
Cat. No.: HY-107315
CAS No.: 443683-76-9
Category:  

Triterpenes Alisma plantago-aquatica Linn. Terpenoids Plants Alismataceae

Target:  

HBV Apoptosis

Alisol F 24-acetate is a triterpene compound that can be isolated from the rhizomes of Alisma orientalis. Alisol F 24-acetate inhibits the secretion of HBV surface antigen HBsAg and HBeAg with IC50 values of 7.7 µM and 5.1 µM. Alisol F 24-acetate has proapoptotic activity and can be used for cancer research .
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Alisol B acetate
Alisol B acetate
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Cat. No.: HY-126365
CAS No.: 19865-76-0
Category:  

Triterpenes Alisma plantago-aquatica Linn. Terpenoids Plants Alismataceae

Target:  

Apoptosis Caspase PI3K Akt

Alisol B acetate is a Triterpenoids product that can be isolated from the tubers of Alisma plantago-aquatica Linn. .
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Alisol E 23-acetate
Alisol E 23-acetate
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Cat. No.: HY-N8635
CAS No.: 155301-58-9
Category:  

Triterpenes Alisma plantago-aquatica Linn. Terpenoids Plants Alismataceae

Target:  

Others

Alisol E 23-acetate is a Triterpenoids product that can be isolated from the tubers of Alisma plantago-aquatica Linn. .
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Alisol O
Alisol O
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Cat. No.: HY-129161
CAS No.: 928148-51-0
Category:  

Triterpenes Alisma plantago-aquatica Linn. Terpenoids Plants Alismataceae

Target:  

Others

Alisol O is a Triterpenoids product that can be isolated from the tubers of Alisma plantago-aquatica Linn. .
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