BCA

By Targets:	Adrenergic Receptor (5) Apoptosis (1) Beta-secretase (1) Carbonic Anhydrase (2) CXCR (2) EGFR (1) GABA Receptor (2) Imidazoline Receptor (5) Isotope-Labeled Compounds (1) Liposome (3) Monoamine Oxidase (5) nAChR (2) Opioid Receptor (2) Reference Standards (1) Small Interfering RNA (siRNA) (9) TGF-beta/Smad (1) TGF-β Receptor (1) WDR5 (1)
By Research Areas:	Cancer (9) Cardiovascular Disease (1) Inflammation/Immunology (4) Metabolic Disease (1) Neurological Disease (7)
Oligonucleotides:	Pegylated Lipids (3) Rat Pre-designed siRNA Sets (2) Mouse Pre-designed siRNA Sets (3) Human Pre-designed siRNA Sets (4) siRNAs (9)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-16993

OICR-9429 Maximum Cited Publications 15 Publications Verification	Apoptosis WDR5	Cancer
OICR-9429, a chemical probe, is high affinity WD repeat domain 5 (WDR5) inhibitor, competitively blocks WDR5 interaction with MLL protein via binding the central peptide-binding pocket of WDR5. OICR-9429 can suppress histone H3K4 trimethylation and can be used for the research of various cancers including non-MLL-rearranged leukaemia, colon, pancreatic, prostate cancer and bladder cancer (BCa) .

HY-101392

Harmane 1 Publications Verification	Imidazoline Receptor Monoamine Oxidase Adrenergic Receptor nAChR GABA Receptor Opioid Receptor	Neurological Disease Inflammation/Immunology
Harmane is a benzodiazepine receptor inhibitor (IC₅₀=7 μM), with IC₅₀ values for mACh, Opioid Receptor, MAO-A/B, and α2-adrenergic receptor of 24 μM, 2.8 μM, 0.5 μM, 5 μM, and 18 μM, respectively. Harmane inhibits the I1 imidazoline receptor (IC₅₀ = 30 nM) to reduce blood pressure and has antidepressant, anti-anxiety, anticonvulsant, and analgesic effects. Harmane inhibits dopamine biosynthesis by decreasing tyrosine hydroxylase (TH) activity and enhancing L-DOPA-induced cytotoxicity in PC12 cells. Additionally, Harmane can increase the mutagenic effect induced by 2-acetylaminofluorene (AAF) .

HY-15908

*BCA* 5+ Cited Publications Disodium bicinchoninate	Beta-secretase	Neurological Disease Cancer
BCA (Disodium bicinchoninate) is an orally active and non-competitive Beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor with an IC₅₀ value of 28 µM, a K_i value of 43 µM. BCA shows anticancer activity. BCA has the potential for the research of Alzheimer's disease (AD) .

HY-P990957

Ficerafusp alfa BCA-101; FMAB2	EGFR TGF-beta/Smad	Inflammation/Immunology Cancer
Ficerafusp alfa (BCA-101) is a bispecific antibody targeting EGFR and TGFβ, with a K_d of 2.58 nM against EGFR and a K_d of 61.3 nM against TGFβ1. Ficerafusp alfa binds to EGFR, inhibits EGFR phosphorylation, blocks EGF-dependent cell proliferation, and mediates antibody-dependent cellular cytotoxicity against EGFR-positive tumor cells. Ficerafusp alfa sequesters TGFβ via its TGFβRII ECD domain, neutralizes the activity of TGFβ and TGFβ1, and blocks TGFβ-dependent processes, including epithelial-mesenchymal transition, cell invasion, and differentiation of inducible regulatory T cells. Ficerafusp alfa is applicable to research related to head and neck squamous cell carcinoma, advanced solid tumors, squamous non-small cell lung cancer, anal squamous cell carcinoma, colorectal cancer, and pancreatic cancer .

HY-W440823A

DSPE-PEG1000-Amine ammonium DSPE-PEG1000-NH2 ammonium	Liposome	Cancer
DSPE-PEG1000-Amine (DSPE-PEG1000-NH2) ammonium is a 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol conjugate with a terminal amino group. DSPE-PEG1000-Amine ammonium can functionalize the surface of PLGA-lecithin-PEG core-shell nanoparticles to introduce positive surface charges. The amino group of DSPE-PEG1000-Amine ammonium can be converted into an aromatic aldehyde to react with the acetone-protected aromatic hydrazide on the surface of bovine carbonic anhydrase (BCA) molecules .

HY-P991567

VX5 VX5/5261	CXCR	Inflammation/Immunology Cancer
VX5 (VX5/5261) is a humanized IgG1κ monoclonal antibody inhibitor targeting *BCA-1/CXCL13. VX5 significantly inhibits human CXCL13-mediated internalization of CXCR5*, blocks both human and mouse CXCL13-dependent B-cells chemotaxis and migration. VX5 can be used to study autoimmune diseases like multiple sclerosis and arthritis, and cancers like gastric lymphomas and colon cancer .

HY-101392A

Harmane hydrochloride 1 Publications Verification	Imidazoline Receptor Monoamine Oxidase Adrenergic Receptor nAChR GABA Receptor Opioid Receptor	Neurological Disease Inflammation/Immunology
Harmane hydrochloride is a benzodiazepine receptor inhibitor (IC₅₀=7 μM), with IC₅₀ values for mACh, Opioid Receptor, MAO-A/B, and α2-adrenergic receptor of 24 μM, 2.8 μM, 0.5 μM, 5 μM, and 18 μM, respectively. Harmane hydrochloride inhibits the I1 imidazoline receptor (IC₅₀ = 30 nM) to reduce blood pressure and has antidepressant, anti-anxiety, anticonvulsant, and analgesic effects. Harmane hydrochloride inhibits dopamine biosynthesis by decreasing tyrosine hydroxylase (TH) activity and enhancing L-DOPA-induced cytotoxicity in PC12 cells. Additionally, Harmane hydrochloride can increase the mutagenic effect induced by 2-acetylaminofluorene (AAF) .

HY-P99959

Unasnemab MT-3921; rH116A3	TGF-β Receptor	Neurological Disease
Unasnemab (MT-3921) is a humanised IgG1 monoclonal antibody that binds to repulsive guidance molecule A (RGMa). Unasnemab improves locomotor function and promotes neuroregeneration. Unasnemab exerts ameliorative effects on hippocampal neurogenesis impairment and cognitive decline in db/db mice, Streptozotocin (STZ) (HY-13753)-induced type 1 diabetic and bilateral common carotid artery stenosis (BCAS)-induced mice. Unasnemab can be used for the research of spinal cord injury, diabetes-induced neurological impairments .

HY-155908

DSPE-PEG10000-Amine ammonium DSPE-PEG10000-NH2 ammonium	Liposome	Others
DSPE-PEG10000-Amine ammonium is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG10000-Amine ammonium can be converted into aromatic aldehydes by reacting with acetone-protected aromatic hydrazines on the surface of bovine carbonic anhydrase (BCA) molecules. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

HY-155907

DSPE-PEG5000-Amine ammonium DSPE-PEG5000-NH2 ammonium	Liposome	Others
DSPE-PEG5000-Amine ammonium is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. DSPE-PEG5000-Amine ammonium amino group can be converted to aromatic aldehydes that react with acetone-protected aromatic hydrazides on the surface of the bovine carbonic anhydrase (BCA) molecule. Liposomes produce liposome-Bah-BCA conjugates by forming diaryl hydrazone (BAH) with target enzyme molecules. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

HY-W031519

Chloraminophenamide	Carbonic Anhydrase	Cardiovascular Disease
Chloraminophenamide (Compound 14) is a carbonic anhydrase inhibitor, with K_is of 75, 160 and 8400 nM for hCA II*, bCA* IV and hCA I, respectively. Chloraminophenamide has the potential for antiglaucoma research .**

HY-32933

4-Acetylphenylboronic acid	Carbonic Anhydrase	Metabolic Disease
4-Acetylphenylboronic acid is a potent inhibitor of carbonic anhydrases II(CA II), with IC₅₀s of 246 μM and 281.40 μM for bovine CA II (bCA II) and human CA II (hCA II). 4-Acetylphenylboronic acid can be obtained via mechanochemistry and solvent evaporation. 4-Acetylphenylboronic acid has a loss of the carbonyl group at 500-550 K .

HY-101392R

Harmane (Standard)	Reference Standards Imidazoline Receptor Monoamine Oxidase Adrenergic Receptor	Neurological Disease Cancer
Harmane (Standard) is the analytical standard of Harmane. This product is intended for research and analytical applications. Harmane, a β-Carboline alkaloid (BCA), is a potent neurotoxin that causes severe action tremors and psychiatric manifestations. Harmane shows 1000-fold selectivity for I1-Imidazoline receptor (IC₅₀=30 nM) over α2-adrenoceptor (IC₅₀=18 μM). Harmane is also a potent and selective inhibitor of monoamine oxidase (MAO) (IC₅₀s=0.5 and 5 μM for human MAO A/B, respectively). Harmane exhibits comutagenic effect .

HY-RS17759

Bcas2 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Bcas2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Bcas2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Bcas2 Mouse Pre-designed siRNA Set A Bcas2 Mouse Pre-designed siRNA Set A

HY-RS24226

Bcas2 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Bcas2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Bcas2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Bcas2 Rat Pre-designed siRNA Set A Bcas2 Rat Pre-designed siRNA Set A

HY-RS01400

BCAS2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
BCAS2 Human Pre-designed siRNA Set A contains three designed siRNAs for BCAS2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

BCAS2 Human Pre-designed siRNA Set A BCAS2 Human Pre-designed siRNA Set A

HY-RS01399

BCAS1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
BCAS1 Human Pre-designed siRNA Set A contains three designed siRNAs for BCAS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

BCAS1 Human Pre-designed siRNA Set A BCAS1 Human Pre-designed siRNA Set A

HY-RS01401

BCAS3 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
BCAS3 Human Pre-designed siRNA Set A contains three designed siRNAs for BCAS3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

BCAS3 Human Pre-designed siRNA Set A BCAS3 Human Pre-designed siRNA Set A

HY-RS21300

Blnk Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Blnk Mouse Pre-designed siRNA Set A contains three designed siRNAs for Blnk gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Blnk Mouse Pre-designed siRNA Set A Blnk Mouse Pre-designed siRNA Set A

HY-RS01522

BLNK Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
BLNK Human Pre-designed siRNA Set A contains three designed siRNAs for BLNK gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

BLNK Human Pre-designed siRNA Set A BLNK Human Pre-designed siRNA Set A

HY-101392S

Harmane-d1	Imidazoline Receptor Monoamine Oxidase Adrenergic Receptor	Neurological Disease Cancer
Harmane-d is the deuterium labeled Harmane. Harmane, a β-Carboline alkaloid (BCA), is a potent neurotoxin that causes severe action tremors and psychiatric manifestations. Harmane shows 1000-fold selectivity for I1-Imidazoline receptor (IC₅₀=30 nM) over α2-adrenoceptor (IC₅₀=18 μM). Harmane is also a potent and selective inhibitor of monoamine oxidase (MAO) (IC₅₀s=0.5 and 5 μM for human MAO A/B, respectively) .

HY-101392S1

Harmane-d2	Isotope-Labeled Compounds Imidazoline Receptor Monoamine Oxidase Adrenergic Receptor	Neurological Disease Cancer
Harmane-d₂ is the deuterium labeled Harmane. Harmane, a β-Carboline alkaloid (BCA), is a potent neurotoxin that causes severe action tremors and psychiatric manifestations. Harmane shows 1000-fold selectivity for I1-Imidazoline receptor (IC₅₀=30 nM) over α2-adrenoceptor (IC₅₀=18 μM). Harmane is also a potent and selective inhibitor of monoamine oxidase (MAO) (IC₅₀s=0.5 and 5 μM for human MAO A/B, respectively) .

HY-P992476

TJX7	CXCR	Cancer
TJX7 is a recombinant antibody targeting *CXCL13/BCA-1/BLC*.

HY-D3068

LDs-BCA

HY-RS28929

Bcas1 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Bcas1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Bcas1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Bcas1 Rat Pre-designed siRNA Set A Bcas1 Rat Pre-designed siRNA Set A

HY-RS22405

Bcas1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Bcas1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Bcas1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Bcas1 Mouse Pre-designed siRNA Set A Bcas1 Mouse Pre-designed siRNA Set A

Cat. No.	Product Name	Type

HY-D3068

LDs-BCA	Fluorescent Dye

Cat. No.	Product Name	Type

HY-15908

*BCA* 5+ Cited Publications Disodium bicinchoninate	Biochemical Assay Reagents
BCA (Disodium bicinchoninate) is an orally active and non-competitive Beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor with an IC₅₀ value of 28 µM, a K_i value of 43 µM. BCA shows anticancer activity. BCA has the potential for the research of Alzheimer's disease (AD) .

HY-W440823A

DSPE-PEG1000-Amine ammonium DSPE-PEG1000-NH2 ammonium	Biochemical Assay Reagents
DSPE-PEG1000-Amine (DSPE-PEG1000-NH2) ammonium is a 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol conjugate with a terminal amino group. DSPE-PEG1000-Amine ammonium can functionalize the surface of PLGA-lecithin-PEG core-shell nanoparticles to introduce positive surface charges. The amino group of DSPE-PEG1000-Amine ammonium can be converted into an aromatic aldehyde to react with the acetone-protected aromatic hydrazide on the surface of bovine carbonic anhydrase (BCA) molecules .

DSPE-PEG1000-Amine ammonium

DSPE-PEG1000-NH2 ammonium

Biochemical Assay Reagents

DSPE-PEG1000-Amine (DSPE-PEG1000-NH2) ammonium is a 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol conjugate with a terminal amino group. DSPE-PEG1000-Amine ammonium can functionalize the surface of PLGA-lecithin-PEG core-shell nanoparticles to introduce positive surface charges. The amino group of DSPE-PEG1000-Amine ammonium can be converted into an aromatic aldehyde to react with the acetone-protected aromatic hydrazide on the surface of bovine carbonic anhydrase (BCA) molecules .

HY-155908

DSPE-PEG10000-Amine ammonium DSPE-PEG10000-NH2 ammonium	Biochemical Assay Reagents
DSPE-PEG10000-Amine ammonium is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG10000-Amine ammonium can be converted into aromatic aldehydes by reacting with acetone-protected aromatic hydrazines on the surface of bovine carbonic anhydrase (BCA) molecules. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

DSPE-PEG10000-Amine ammonium

DSPE-PEG10000-NH2 ammonium

Biochemical Assay Reagents

DSPE-PEG10000-Amine ammonium is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG10000-Amine ammonium can be converted into aromatic aldehydes by reacting with acetone-protected aromatic hydrazines on the surface of bovine carbonic anhydrase (BCA) molecules. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

HY-155907

DSPE-PEG5000-Amine ammonium DSPE-PEG5000-NH2 ammonium	Biochemical Assay Reagents
DSPE-PEG5000-Amine ammonium is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. DSPE-PEG5000-Amine ammonium amino group can be converted to aromatic aldehydes that react with acetone-protected aromatic hydrazides on the surface of the bovine carbonic anhydrase (BCA) molecule. Liposomes produce liposome-Bah-BCA conjugates by forming diaryl hydrazone (BAH) with target enzyme molecules. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

DSPE-PEG5000-Amine ammonium

DSPE-PEG5000-NH2 ammonium

Biochemical Assay Reagents

DSPE-PEG5000-Amine ammonium is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. DSPE-PEG5000-Amine ammonium amino group can be converted to aromatic aldehydes that react with acetone-protected aromatic hydrazides on the surface of the bovine carbonic anhydrase (BCA) molecule. Liposomes produce liposome-Bah-BCA conjugates by forming diaryl hydrazone (BAH) with target enzyme molecules. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

Cat. No.	Product Name

HY-K2002

BCA Protein Assay Kit 1 Publications Verification
MCE BCA Protein Assay Kit is a colorimetric assay based on the bicinchoninic acid (BCA) reaction principle for quantitative protein determination.

Cat. No.	Product Name	Target	Research Area	Image

HY-P990957

Ficerafusp alfa BCA-101; FMAB2	EGFR TGF-beta/Smad	Inflammation/Immunology Cancer
Ficerafusp alfa (BCA-101) is a bispecific antibody targeting EGFR and TGFβ, with a K_d of 2.58 nM against EGFR and a K_d of 61.3 nM against TGFβ1. Ficerafusp alfa binds to EGFR, inhibits EGFR phosphorylation, blocks EGF-dependent cell proliferation, and mediates antibody-dependent cellular cytotoxicity against EGFR-positive tumor cells. Ficerafusp alfa sequesters TGFβ via its TGFβRII ECD domain, neutralizes the activity of TGFβ and TGFβ1, and blocks TGFβ-dependent processes, including epithelial-mesenchymal transition, cell invasion, and differentiation of inducible regulatory T cells. Ficerafusp alfa is applicable to research related to head and neck squamous cell carcinoma, advanced solid tumors, squamous non-small cell lung cancer, anal squamous cell carcinoma, colorectal cancer, and pancreatic cancer .

HY-P991567

VX5 VX5/5261	CXCR	Inflammation/Immunology Cancer
VX5 (VX5/5261) is a humanized IgG1κ monoclonal antibody inhibitor targeting *BCA-1/CXCL13. VX5 significantly inhibits human CXCL13-mediated internalization of CXCR5*, blocks both human and mouse CXCL13-dependent B-cells chemotaxis and migration. VX5 can be used to study autoimmune diseases like multiple sclerosis and arthritis, and cancers like gastric lymphomas and colon cancer .

HY-P99959

Unasnemab MT-3921; rH116A3	TGF-β Receptor	Neurological Disease
Unasnemab (MT-3921) is a humanised IgG1 monoclonal antibody that binds to repulsive guidance molecule A (RGMa). Unasnemab improves locomotor function and promotes neuroregeneration. Unasnemab exerts ameliorative effects on hippocampal neurogenesis impairment and cognitive decline in db/db mice, Streptozotocin (STZ) (HY-13753)-induced type 1 diabetic and bilateral common carotid artery stenosis (BCAS)-induced mice. Unasnemab can be used for the research of spinal cord injury, diabetes-induced neurological impairments .

HY-P992476

TJX7	CXCR	Cancer
TJX7 is a recombinant antibody targeting *CXCL13/BCA-1/BLC*.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-101392

Harmane 1 Publications Verification	Alkaloids other families Pyridine Alkaloids Plants Indole Alkaloids Source Classification	Imidazoline Receptor Monoamine Oxidase Adrenergic Receptor nAChR GABA Receptor Opioid Receptor
Harmane is a benzodiazepine receptor inhibitor (IC₅₀=7 μM), with IC₅₀ values for mACh, Opioid Receptor, MAO-A/B, and α2-adrenergic receptor of 24 μM, 2.8 μM, 0.5 μM, 5 μM, and 18 μM, respectively. Harmane inhibits the I1 imidazoline receptor (IC₅₀ = 30 nM) to reduce blood pressure and has antidepressant, anti-anxiety, anticonvulsant, and analgesic effects. Harmane inhibits dopamine biosynthesis by decreasing tyrosine hydroxylase (TH) activity and enhancing L-DOPA-induced cytotoxicity in PC12 cells. Additionally, Harmane can increase the mutagenic effect induced by 2-acetylaminofluorene (AAF) .

HY-101392A

Harmane hydrochloride 1 Publications Verification	Apocynaceae Alkaloids Other Alkaloids Plants Rauwolfia canescens Source Classification	Imidazoline Receptor Monoamine Oxidase Adrenergic Receptor nAChR GABA Receptor Opioid Receptor
Harmane hydrochloride is a benzodiazepine receptor inhibitor (IC₅₀=7 μM), with IC₅₀ values for mACh, Opioid Receptor, MAO-A/B, and α2-adrenergic receptor of 24 μM, 2.8 μM, 0.5 μM, 5 μM, and 18 μM, respectively. Harmane hydrochloride inhibits the I1 imidazoline receptor (IC₅₀ = 30 nM) to reduce blood pressure and has antidepressant, anti-anxiety, anticonvulsant, and analgesic effects. Harmane hydrochloride inhibits dopamine biosynthesis by decreasing tyrosine hydroxylase (TH) activity and enhancing L-DOPA-induced cytotoxicity in PC12 cells. Additionally, Harmane hydrochloride can increase the mutagenic effect induced by 2-acetylaminofluorene (AAF) .

HY-101392R

Harmane (Standard)	Alkaloids other families Plants Source Classification	Reference Standards Imidazoline Receptor Monoamine Oxidase Adrenergic Receptor
Harmane (Standard) is the analytical standard of Harmane. This product is intended for research and analytical applications. Harmane, a β-Carboline alkaloid (BCA), is a potent neurotoxin that causes severe action tremors and psychiatric manifestations. Harmane shows 1000-fold selectivity for I1-Imidazoline receptor (IC₅₀=30 nM) over α2-adrenoceptor (IC₅₀=18 μM). Harmane is also a potent and selective inhibitor of monoamine oxidase (MAO) (IC₅₀s=0.5 and 5 μM for human MAO A/B, respectively). Harmane exhibits comutagenic effect .

Species:	Human (3) Rat (1) Mouse (2) Cynomolgus (1) Pig (1)
Tag:	His (6) Tag Free (1) GST (1) Fc (1)
Source:	HEK293 (2) E. coli (6)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P77911

	BCA-1/CXCL13 Protein, Mouse (HEK293, His) 1 Publications Verification ANGIE; ANGIE2; BCA-1; BCA1; BLC; BLR1L; SCYB13	Mouse	HEK293
	CXCL13, known as BCA-1 (B cell-attracting chemokine 1) or BLC (B-lymphocyte chemoattractant), is an efficacious attractant selective for B lymphocytes through binding to the BLR1/CXCR5 receptor. CXCL13 is a homeostatic chemokine, and is constitutively secreted by stromal cells in B-cell areas of secondary lymphoid tissues (follicles), such as spleen, lymph nodes, tonsils, and Peyer's patches. BCA-1/CXCL13 Protein, Mouse (HEK293, His) is produced in HEK293 cells with a N-Terminal His-tag. It consists of 88 amino acids (I22-A109).

HY-P77912

	BCA-1/CXCL13 Protein, Mouse (HEK293, Fc) 1 Publications Verification ANGIE; ANGIE2; BCA-1; BCA1; BLC; BLR1L; SCYB13	Mouse	HEK293
	CXCL13, known as BCA-1 (B cell-attracting chemokine 1) or BLC (B-lymphocyte chemoattractant), is an efficacious attractant selective for B lymphocytes through binding to the BLR1/CXCR5 receptor. CXCL13 is a homeostatic chemokine, and is constitutively secreted by stromal cells in B-cell areas of secondary lymphoid tissues (follicles), such as spleen, lymph nodes, tonsils, and Peyer's patches. BCA-1/CXCL13 Protein, Mouse (HEK293, Fc) is produced in HEK293 cells with a N-Terminal Fc-tag. It consists of 88 amino acids (I22-A109).

HY-P704362

	BCA-1/CXCL13 Protein, Human (His) BCA-1/CXCL13; C-X-C motif chemokine 13; BCA1; BLC; SCYB13	Human	E. coli
	The BCA-1/CXCL13 protein selectively attracts B lymphocytes without affecting T lymphocytes, monocytes, or neutrophils. Unlike other chemokines, it does not induce calcium release from B lymphocytes. BCA-1/CXCL13 Protein, Human (His) is the recombinant human-derived BCA-1/CXCL13 protein, expressed by E. coli, with N-His labeled tag.

HY-P700044AF

	*Animal-Free BCA-1/CXCL13 Protein, Human (His)* BCA-1/CXCL13; C-X-C motif chemokine 13; BCA1; BLC; SCYB13	Human	E. coli
	The BCA-1/CXCL13 protein selectively attracts B lymphocytes without affecting T lymphocytes, monocytes, or neutrophils. Unlike other chemokines, it does not induce calcium release from B lymphocytes. Animal-Free BCA-1/CXCL13 Protein, Human (His) is the recombinant human-derived animal-FreeBCA-1/CXCL13 protein, expressed by E. coli , with N-His labeled tag. This product is for cell culture use only.

HY-P76164

	BCA-1/CXCL13 Protein, Cynomolgus (His) C-X-C motif chemokine 13; BCA1; BLC; SCYB13	Cynomolgus	E. coli
	CXCL13, known as BCA-1 (B cell-attracting chemokine 1) or BLC (B-lymphocyte chemoattractant), is an efficacious attractant selective for B lymphocytes through binding to the BLR1/CXCR5 receptor. CXCL13 is a homeostatic chemokine, and is constitutively secreted by stromal cells in B-cell areas of secondary lymphoid tissues (follicles), such as spleen, lymph nodes, tonsils, and Peyer's patches. BCA-1/CXCL13 Protein, Cynomolgus (His) is produced in E. coli with a N-Terminal His-tag.

HY-P7131

	BCA-1/CXCL13 Protein, Human 3 Publications Verification rHuBCA-1/CXCL13; C-X-C motif chemokine 13; BCA1; BLC; SCYB13	Human	E. coli
	CXCL13, known as BCA-1 (B cell-attracting chemokine 1) or BLC (B-lymphocyte chemoattractant), is an efficacious attractant selective for B lymphocytes through binding to the BLR1/CXCR5 receptor. CXCL13 is a homeostatic chemokine, and is constitutively secreted by stromal cells in B-cell areas of secondary lymphoid tissues (follicles), such as spleen, lymph nodes, tonsils, and Peyer's patches. BCA-1/CXCL13 Protein, Human is produced in E. coli, and consists of 87 amino acids (V23-P109).

HY-P700547

	BCA-1/CXCL13 Protein, Rat (His-GST) rHuBCA-1/CXCL13; C-X-C motif chemokine 13; BCA1; BLC; SCYB13	Rat	E. coli
	The BCA-1/CXCL13 protein is a member of the intercrine α family and is critical for chemokines involved in intercellular communication and immune responses. As part of this family, BCA-1/CXCL13 may play a key role in regulating inflammatory processes and influencing cellular interactions. BCA-1/CXCL13 Protein, Rat (His-GST) is the recombinant rat-derived BCA-1/CXCL13 protein, expressed by E. coli , with N-GST, N-6*His labeled tag.

HY-P700234AF

	Animal-Free CXCL13 Protein, Pig (His) C-X-C motif chemokine 13; BCA1; BLC; SCYB13	Pig	E. coli
	The CXCL13 protein is a member of the intercrine α family and is critical for chemokines involved in intercellular communication and immune responses. In this family, CXCL13 may play a key role in regulating inflammatory processes and influencing cellular interactions. Animal-Free CXCL13 Protein, Pig (His) is the recombinant pig-derived animal-FreeCXCL13 protein, expressed by E. coli , with N-His labeled tag. This product is for cell culture use only.

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Cat. No.	Product Name	Chemical Structure

HY-101392S

Harmane-d1

Harmane-d is the deuterium labeled Harmane. Harmane, a β-Carboline alkaloid (BCA), is a potent neurotoxin that causes severe action tremors and psychiatric manifestations. Harmane shows 1000-fold selectivity for I1-Imidazoline receptor (IC₅₀=30 nM) over α2-adrenoceptor (IC₅₀=18 μM). Harmane is also a potent and selective inhibitor of monoamine oxidase (MAO) (IC₅₀s=0.5 and 5 μM for human MAO A/B, respectively) .

HY-101392S1

Harmane-d2

Harmane-d₂ is the deuterium labeled Harmane. Harmane, a β-Carboline alkaloid (BCA), is a potent neurotoxin that causes severe action tremors and psychiatric manifestations. Harmane shows 1000-fold selectivity for I1-Imidazoline receptor (IC₅₀=30 nM) over α2-adrenoceptor (IC₅₀=18 μM). Harmane is also a potent and selective inhibitor of monoamine oxidase (MAO) (IC₅₀s=0.5 and 5 μM for human MAO A/B, respectively) .

Host:	Mouse (2) Rabbit (1)
Reactivity:	Human (3)
Application:	IHC-P (3) ICC/IF (1) WB (1)
Isotype:	IgG (1) IgG1 (2)
Conjugation:	Non-conjugated (3)
Clonality:	Monoclonal (2) Recombinant (1)
Modification:	Unmodified (2)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P88968

	AKIP1 Antibody (YA8652) BCA3; C11orf17	IHC-P	Human
	AKIP1 Antibody (YA8652) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to AKIP1.

HY-P88968A

	AKIP1 Antibody (YA8652)(PBS only) BCA3; C11orf17	IHC-P	Human
	AKIP1 Antibody (YA8652) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to AKIP1.

HY-P87311

	CXCL13 Antibody (YA6994) ANGIE antibody; ANGIE2 antibody; B cell attracting chemokine 1 antibody; B cell-attracting chemokine 1 antibody; B lymphocyte chemoattractant antibody; B-cell chemoattractant antibody; B-cell-attracting chemokine 1 antibody; B-cell-homing chemokine (ligand for Burkitt's lymphoma receptor-1) antibody; BCA-1 antibody; BCA1 antibody	WB, ICC/IF, IHC-P	Human
	CXCL13 Antibody (YA6994) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CXCL13.

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Cat. No.	Product Name		Classification

HY-W440823A

DSPE-PEG1000-Amine ammonium DSPE-PEG1000-NH2 ammonium		Pegylated Lipids
DSPE-PEG1000-Amine (DSPE-PEG1000-NH2) ammonium is a 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol conjugate with a terminal amino group. DSPE-PEG1000-Amine ammonium can functionalize the surface of PLGA-lecithin-PEG core-shell nanoparticles to introduce positive surface charges. The amino group of DSPE-PEG1000-Amine ammonium can be converted into an aromatic aldehyde to react with the acetone-protected aromatic hydrazide on the surface of bovine carbonic anhydrase (BCA) molecules .

HY-155908

DSPE-PEG10000-Amine ammonium DSPE-PEG10000-NH2 ammonium		Pegylated Lipids
DSPE-PEG10000-Amine ammonium is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG10000-Amine ammonium can be converted into aromatic aldehydes by reacting with acetone-protected aromatic hydrazines on the surface of bovine carbonic anhydrase (BCA) molecules. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

HY-155907

DSPE-PEG5000-Amine ammonium DSPE-PEG5000-NH2 ammonium		Pegylated Lipids
DSPE-PEG5000-Amine ammonium is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. DSPE-PEG5000-Amine ammonium amino group can be converted to aromatic aldehydes that react with acetone-protected aromatic hydrazides on the surface of the bovine carbonic anhydrase (BCA) molecule. Liposomes produce liposome-Bah-BCA conjugates by forming diaryl hydrazone (BAH) with target enzyme molecules. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

HY-RS17759

Bcas2 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Bcas2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Bcas2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS24226

Bcas2 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Bcas2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Bcas2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS01400

BCAS2 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
BCAS2 Human Pre-designed siRNA Set A contains three designed siRNAs for BCAS2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS01399

BCAS1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
BCAS1 Human Pre-designed siRNA Set A contains three designed siRNAs for BCAS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS01401

BCAS3 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
BCAS3 Human Pre-designed siRNA Set A contains three designed siRNAs for BCAS3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS21300

Blnk Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Blnk Mouse Pre-designed siRNA Set A contains three designed siRNAs for Blnk gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS01522

BLNK Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
BLNK Human Pre-designed siRNA Set A contains three designed siRNAs for BLNK gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS28929

Bcas1 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Bcas1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Bcas1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS22405

Bcas1 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Bcas1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Bcas1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
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Fluorescent Dye

Biochemical Assay Reagents

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Recombinant Proteins

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