35 Results for "

CD16a

" in MedChemExpress (MCE) Product Catalog:
Products (35)

35 Results for "CD16a" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P70705
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Low Affinity Immunoglobulin Gamma Fc Region Receptor III-A; CD16a Antigen; Fc-Gamma RIII-Alpha; Fc-Gamma RIII; Fc-gamma RIIIa; FcRIII; FcRIIIa; FcR-10; IgG Fc Receptor III-2; CD16a; FCGR3A; CD16a; FCG3; FCGR3; IGFR3
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Cat. No.: HY-P990710
CAS No.: 2738880-26-5
Synonyms: AFM13

Target:  

TNF Receptor

Research Areas:  

Cancer

Acimtamig (AFM13) is a CD30/CD16A bispecific innate cell engager. Acimtamig binds to the CD16A expressed on natural killer (NK) cells and binds to CD30 on CD30-expressing tumor cells, thereby selectively cross-linking tumor and NK cells. Acimtamig can be used for the study of eripheral T-cell lymphoma (PTCL) .
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Cat. No.: HY-P991223

Research Areas:  

Cancer

NC762 is a humanized IgG1κ monoclonal antibody that targets human B7-H4 (B7 homolog 4). NC762 has enhanced binding to CD16a (FcγRIIIa) after being Fc engineered with three point mutations (S239D/A330L/I332E; DLE) and demonstrate increased antibody-dependent cellular cytotoxicity (ADCC) activity. NC762 inhibits tumor growth in vivo through binding to tumor-expressing B7-H4. NC762 can be studies in research on cancer such as advanced or metastatic solid tumors .
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Cat. No.: HY-P991665
Synonyms: OBT357NF; OBT357

Research Areas:  

Cancer

MEN1112 (OBT357NF; OBT357) is a defucosylated humanized monoclonal antibody targeting Bst1/CD157, with an EC50 of 0.4 nM. MEN1112 binds to Bst1/CD157 on acute myeloid leukemia cells, triggers slow antigen internalization, induces antibody-dependent cell-mediated cytotoxicity, and mediates the lysis of acute myeloid leukemia cells and blasts. MEN1112 is applicable for research related to acute myeloid leukemia .
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Cat. No.: HY-P991998

Target:  

Fc Receptor (FcR)

Research Areas:  

Inflammation/Immunology Cancer

Anti-Human/Monkey CD16a Antibody (3G8) is a monoclonal antibody targeting CD16a. Anti-Human/Monkey CD16a Antibody (3G8) blocks FcγRIII/CD16a, upregulates the metabolic activity of CD16+ cells, downregulates CD87, a poor prognostic marker, and inhibits the engraftment and growth of leukemia cells in acute myeloid leukemia, and rapidly increases platelet counts in immune thrombocytopenia. Anti-Human/Monkey CD16a Antibody (3G8) is applicable to research related to tumor immunology .
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Cat. No.: HY-P990905
CAS No.: 2871775-98-1
Synonyms: SAR-443579

Target:  

Interleukin Related

Research Areas:  

Cancer

Bexatamig (SAR-443579) is a trifunctional natural killer cell engager targeting IL-3R α/CD123, NKp46/NCR1/CD335 and Fc gamma RIIIA/CD16a. Bexatamig forms a cytolytic synapse between natural killer cells and CD123-positive tumor cells. By activating natural killer cells to induce tumor cell death, Bexatamig effectively reduces the burden of CD123-positive acute myeloid leukemia (AML) blasts. Bexatamig has been granted FDA Fast Track designation, and is primarily investigated for relapsed or refractory acute myeloid leukemia, B-cell acute lymphoblastic leukemia, and high-risk myelodysplastic syndromes .
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Cat. No.: HY-P991997

Target:  

Fc Receptor (FcR)

Research Areas:  

Others

Anti-CD16a Antibody (3G8) is a pan-CD16-specific antibody. Anti-CD16a Antibody (3G8) binds to an epitope overlapping with CD16a’s Fc binding site, inhibiting CD16a-IgG Fc region interactions.Anti-CD16a Antibody (3G8) recognizes CD16a, CD16b, and CD16b-NA1 and NA2 allelotypes expressed by neutrophils .
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Cat. No.: HY-P7806
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rCynFc-gamma receptor 3A/CD16a, His; Low Affinity Immunoglobulin Gamma Fc Region Receptor III-A; CD16a Antigen; Fc-Gamma RIII-Alpha; Fc-Gamma RIII; Fc-gamma RIIIa; FcRIII; FcRIIIa; FcR-10; IgG Fc Receptor III-2; CD16a; FCGR3A; CD16a; FCG3; FCGR3; IGFR3
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Cat. No.: HY-P78676
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FCGR3A; CD16a; FCG3; FCGR3; IGFR3
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Cat. No.: HY-P78677
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FCGR3A; CD16a; FCG3; FCGR3; IGFR3
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Cat. No.: HY-P78678
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FCGR3A; CD16a; FCG3; FCGR3; IGFR3
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Cat. No.: HY-P75207
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Low affinity immunoglobulin gamma Fc region receptor III-A; FcRIIIa; FcR-10; CD16a; FCGR3A; IGFR3
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Cat. No.: HY-P75621A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Low affinity immunoglobulin gamma Fc region receptor III-A; FcRIIIa; FcR-10; CD16a; FCGR3A; IGFR3
Species:  
Rat
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Cat. No.: HY-P75621
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Low affinity immunoglobulin gamma Fc region receptor III-A; FcRIIIa; FcR-10; CD16a; FCGR3A; IGFR3
Species:  
Rat
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Cat. No.: HY-P75210
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Low affinity immunoglobulin gamma Fc region receptor III-A; FcRIIIa; FcR-10; CD16a; FCGR3A; IGFR3
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Cat. No.: HY-P78879
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Low affinity immunoglobulin gamma Fc region receptor III-A; FcRIIIa; FcR-10; CD16a; FCGR3A; IGFR3
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Cat. No.: HY-P72885
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Low affinity immunoglobulin gamma Fc region receptor III-A; FcRIIIa; FcR-10; CD16a; FCGR3A; IGFR3
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Cat. No.: HY-P75209
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Low affinity immunoglobulin gamma Fc region receptor III-A; FcRIIIa; FcR-10; CD16a; FCGR3A; IGFR3
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Cat. No.: HY-P77553
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Low affinity immunoglobulin gamma Fc region receptor III-A; FcRIIIa; FcR-10; CD16a; FCGR3A; IGFR3
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Cat. No.: HY-P77663
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: IgG Fc receptor III; Fc-gamma RIII; FcRIII; FCGR3; CD16; CD16a; FCG3; FcgRIII; FCR-10; FCRIIIA; IGFR3; IMD20
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