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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
59 Results for "
CD22
" in MedChemExpress (MCE) Product Catalog:
Products (59)
59 Results for "CD22" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P99264
CAS No.: 1660159-36-3
Synonyms: Humanized Anti-CD22 Recombinant Antibody
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Mc-Val-Cit-PAB-Cl is a cleavable ADC linker. Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE with IC50s of 3.3 and 0.95 nM for BJAB and WSU cell lines in cytotoxicity assay).
Cat. No.: HY-P9959
CAS No.: 635715-01-4
Synonyms: CMC-544; PF-5208773; WAY-207294
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Inotuzumab ozogamicin (CMC-544) is an antibody-targeted chemotherapy agent composed of a humanized anti-CD22 antibody conjugated to Calicheamicin (HY-19609). Inotuzumab ozogamicin and G544 bind human CD22 with similar affinities (Kd ≈ 150 pM). Inotuzumab ozogamicin has demonstrated efficacy against CD22 + B-cell non-Hodgkin’s lymphoma. Inotuzumab ozogamicin can be used in the research of acute lymphoblastic leukemia .
Cat. No.: HY-P99289
CAS No.: 205923-57-5
Synonyms: Antibody hLL 2; AMG-412
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Cat. No.: HY-P990283
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MCC-DM1 is a agent-Linker Conjugates for ADC such as Anti-CD22-MCC-DM1. MCC-DM1 can be detected in rat and human plasma, feces, and other tissues .
Cat. No.: HY-171138
CAS No.: 1178887-17-6
Synonyms: SET0568
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Mal-VC-PAB-DMEA-PNU-159682 (SET0568) is an antibody-drug conjugate (ADC) drug-linker conjugate. Mal-VC-PAB-DMEA-PNU-159682 is generated by conjugating the potent anti-topoisomerase II inhibitor PNU-159682 (HY-16700) to the lysosomally cleavable dipeptide Mc-VC-PAB, and exhibits strong antitumor activity. Mal-VC-PAB-DMEA-PNU-159682 can be used to synthesize CD22-targeting ADCs, such as Anti-CD22-NMS249 (HY-164761). Mal-VC-PAB-DMEA-PNU-159682 is also applicable to the research of non-Hodgkin's lymphoma .
Cat. No.: HY-P99230
CAS No.: 1639820-81-7
Cat. No.: HY-P991550
CAS No.: 505393-48-6
Cat. No.: HY-P99034
CAS No.: 1622075-65-3
Cat. No.: HY-P99264A
CAS No.: 1660159-36-3
Synonyms: Humanized Anti-CD22 Recombinant Antibody (powder)
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Synonyms: anti-CD22-vc-MMAE; DCDT2980S
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Pinatuzumab vedotin, an antibody-drug conjugate (ADC), is a CD22 humanized monoclonal antibody Pinatuzumab (HY-P99230) conjugated to VcMMAE (HY-15575). Pinatuzumab vedotin has antitumor activities .
Cat. No.: HY-146081
CAS No.: 2493080-27-4
CD22 ligand-1 (compound 12) is a potent and selective CD22 ligand with KD of 0.335, 30.7 µM for hCD22 and MAG, respectively. CD22 ligand-1 has the potential for the research of B-cell related disease .
Cat. No.: HY-RS02210
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CD22 Human Pre-designed siRNA Set A contains three designed siRNAs for CD22 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P990781
CAS No.: 2415439-63-1
Synonyms: SM03
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Cat. No.: HY-P990759
CAS No.: 2795115-07-8
Synonyms: JNJ-75348780
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Cat. No.: HY-RS16690
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Cd22 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cd22 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23125
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Cd22 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cd22 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-164730
Synonyms: ADCT-602; hLL2-Cys-PBD
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Epratuzumab Tesirine (ADCT-602) is a novel CD22-targeted ADC. Epratuzumab Tesirine contains a PBD dimer and a payload SG3249 .
Cat. No.: HY-P990506
Synonyms: NCI m971
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
