CD81

By Targets:	Claudin (1) Fluorescent Dye (1) HBV (1) HCV (2) HIV (1) Liposome (1) Small Interfering RNA (siRNA) (3) Transmembrane Glycoprotein (1) TRP Channel (1)
By Research Areas:	Cancer (2) Cardiovascular Disease (1) Infection (2) Inflammation/Immunology (1)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Phospholipids (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

Targets Recommended: CD1 CD38 CD28 CD19 CD20 CD22 Transferrin Receptor CD3 P-selectin CD6 CD2 CD276/B7-H3 CD73 c-Kit LAG-3 L-Selectin CTLA-4 CD47 ALCAM/CD166 Neprilysin E-Selectin Scavenger Receptor Class B type I (SR-BI） FLT3 Tim3 CD44 Anaplastic lymphoma kinase (ALK) CD74 Human leukocyte immunoglobulin (Ig)-like receptors (LILR) P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P991200

OM-7D3-B3	HCV Claudin	Infection
OM-7D3-B3 is an antibody-based antiviral agent targeting the tight junction protein CLDN1 (K_d=4 nM). By binding to the first extracellular domain of CLDN1, OM-7D3-B3 disrupts the formation of the *CLDN1-CD81* co-receptor complex, thereby effectively inhibiting the entry of hepatitis C virus (HCV). OM-7D3-B3 not only prevents de novo and chronic HCV infections in humanized liver chimeric mice and uPA-SCID mice transplanted with human livers, but also exhibits favorable safety with no toxic effects observed. OM-7D3-B3 serves as a critical tool for research on HCV infection mechanisms and antiviral drug development .

HY-RS17125

Cd81 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Cd81 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cd81 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cd81 Mouse Pre-designed siRNA Set A Cd81 Mouse Pre-designed siRNA Set A

HY-142989

1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine	Liposome HIV HCV HBV	Infection Cancer
1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine is a polyunsaturated phospholipid that serves as a component of lipid monolayers and small unilamellar vesicles. 1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine can be used to prepare endoplasmic reticulum-targeted liposomes (PERLs), which are composed of 1,2-didocosahexaenoyl-sn-glycero-3-phosphoethanolamine, l-α-phosphatidylinositol and l-α-phosphatidylserine at a molar ratio of 1.5:1.5:1:1. PERLs reduce cholesterol levels in human peripheral blood mononuclear cells (PBMCs) and decrease HIV-1 particle secretion from HIV-1-infected PBMCs. Liposomes formed from 1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine exhibit cytotoxicity against leukemia cells. 1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine is applicable to studies related to hepatitis C virus infection, HIV infection, hepatitis B virus infection and leukemia .

HY-RS02270

CD81 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CD81 Human Pre-designed siRNA Set A contains three designed siRNAs for CD81 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CD81 Human Pre-designed siRNA Set A CD81 Human Pre-designed siRNA Set A

HY-RS23570

Cd81 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Cd81 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cd81 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cd81 Rat Pre-designed siRNA Set A Cd81 Rat Pre-designed siRNA Set A

HY-P991933

*Anti-CD81* Antibody**	Transmembrane Glycoprotein	Cancer
Anti-CD81 Antibody is an antibody against human *CD81*. Recommend Isotype Controls:?Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).

HY-N2940

Bisandrographolide A BAA	TRP Channel	Cardiovascular Disease Inflammation/Immunology
Bisandrographolide A (BAA) activates TRPV4 channel with an EC₅₀ of 790-950 nM. Bisandrographolide A can bind to CD81 and suppress its function. Bisandrographolide A is an anti-inflammatory, immunostimulant, and antihypertensive compound .

HY-D3320

APC-AF700	Fluorescent Dye	Others
APC-AF700 is a tandem fluorochrome conjugate for flow cytometry. APC-AF700 can be incorporated into 10-color and 12-color flow cytometry antibody panels (Ex/Em = 633/715 nm) .

Cat. No.	Product Name	Type

HY-D3320

APC-AF700	Fluorescent Dyes
APC-AF700 is a tandem fluorochrome conjugate for flow cytometry. APC-AF700 can be incorporated into 10-color and 12-color flow cytometry antibody panels (Ex/Em = 633/715 nm) .

Cat. No.	Product Name	Type

HY-142989

1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine	Biochemical Assay Reagents
1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine is a polyunsaturated phospholipid that serves as a component of lipid monolayers and small unilamellar vesicles. 1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine can be used to prepare endoplasmic reticulum-targeted liposomes (PERLs), which are composed of 1,2-didocosahexaenoyl-sn-glycero-3-phosphoethanolamine, l-α-phosphatidylinositol and l-α-phosphatidylserine at a molar ratio of 1.5:1.5:1:1. PERLs reduce cholesterol levels in human peripheral blood mononuclear cells (PBMCs) and decrease HIV-1 particle secretion from HIV-1-infected PBMCs. Liposomes formed from 1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine exhibit cytotoxicity against leukemia cells. 1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine is applicable to studies related to hepatitis C virus infection, HIV infection, hepatitis B virus infection and leukemia .

1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine

Biochemical Assay Reagents

1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine is a polyunsaturated phospholipid that serves as a component of lipid monolayers and small unilamellar vesicles. 1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine can be used to prepare endoplasmic reticulum-targeted liposomes (PERLs), which are composed of 1,2-didocosahexaenoyl-sn-glycero-3-phosphoethanolamine, l-α-phosphatidylinositol and l-α-phosphatidylserine at a molar ratio of 1.5:1.5:1:1. PERLs reduce cholesterol levels in human peripheral blood mononuclear cells (PBMCs) and decrease HIV-1 particle secretion from HIV-1-infected PBMCs. Liposomes formed from 1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine exhibit cytotoxicity against leukemia cells. 1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine is applicable to studies related to hepatitis C virus infection, HIV infection, hepatitis B virus infection and leukemia .

Cat. No.	Product Name	Target	Research Area

HY-P3983

*[Cys(Bzl)84] CD (81-92)*	Peptides	Others
[Cys(Bzl)84] CD (81-92) is an acidic peptide. [Cys(Bzl)84] CD (81-92) can be sequencing by negative ion postsource decay (PSD) spectra .

Cat. No.	Product Name

HY-K1068

*Exosome Protein Detection Kit (CD81)*
MCE Exosome Protein Detection Kit (CD81) can specifically detect the exosome marker protein CD81.

Cat. No.	Product Name	Target	Research Area	Image

HY-P991200

OM-7D3-B3	HCV Claudin	Infection
OM-7D3-B3 is an antibody-based antiviral agent targeting the tight junction protein CLDN1 (K_d=4 nM). By binding to the first extracellular domain of CLDN1, OM-7D3-B3 disrupts the formation of the *CLDN1-CD81* co-receptor complex, thereby effectively inhibiting the entry of hepatitis C virus (HCV). OM-7D3-B3 not only prevents de novo and chronic HCV infections in humanized liver chimeric mice and uPA-SCID mice transplanted with human livers, but also exhibits favorable safety with no toxic effects observed. OM-7D3-B3 serves as a critical tool for research on HCV infection mechanisms and antiviral drug development .

HY-P991933

*Anti-CD81* Antibody**	Transmembrane Glycoprotein	Cancer
Anti-CD81 Antibody is an antibody against human *CD81*. Recommend Isotype Controls:?Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N2940

Bisandrographolide A BAA	Structural Classification Acanthaceae Simsia foetida (Cav.) S.F.Blake Terpenoids Diterpenoids Plants Source Classification	TRP Channel
Bisandrographolide A (BAA) activates TRPV4 channel with an EC₅₀ of 790-950 nM. Bisandrographolide A can bind to CD81 and suppress its function. Bisandrographolide A is an anti-inflammatory, immunostimulant, and antihypertensive compound .

Species:	Human (4) Rhesus Macaque/Cynomolgus (1) Mouse (2) Rat (2)
Tag:	SUMO (1) His (4) Tag Free (2) Fc (3)
Source:	HEK293 (8) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P704495

	CD81 Protein-VLP, Human (HEK293) CD81 antigen; CD81 molecule; CD81; CVID6; TAPA1; TAPA-1; TSPAN28	Human	HEK293
	CD81 Protein-VLP, Human (HEK293) is recommended for animal immunization, ELISA. It is not recommended for receptor-ligand interaction detection and SPR/BLI assay since there are other irrelevant membrane proteins of the host on the VLP envelope, and the receptor-ligand interaction will have strong background interference. High requirements for chips and experimental protocols are needed for SPR/BLI assays. If VLP control is required, it is recommended HY-P705433.

HY-P75379

	CD81 Protein, Rat (HEK293) CD81 antigen; CD81; CVID6; TAPA-1; TSPAN28	Rat	HEK293
	CD81, a versatile protein, participates in complement-opsonized particle ingestion, inhibits osteoclast formation, and regulates compartmentalized enzymatic activities. In T cells, CD81 controls intracellular dNTP levels by localizing and degrading SAMHD1. Moreover, it influences cell adhesion and motility, notably in macrophages. CD81 Protein, Rat (HEK293) is the recombinant rat-derived CD81 protein, expressed by HEK293 , with tag free.

HY-P74264

	CD81 Protein, Human (HEK293, His) 2 Publications Verification CD81 antigen; CD81; CVID6; TAPA-1; TSPAN28	Human	HEK293
	The CD19 receptor is critical for B cell activation, driving the trafficking and assembly of CD19-CR2 and BCR complexes, thereby lowering the antigenic threshold for B cell clonal expansion. In T cells, CD19 contributes to CD3 localization and influences polarization. CD81 Protein, Human (HEK293, His) is the recombinant human-derived CD81 protein, expressed by HEK293 , with N-His labeled tag.

HY-P74262

	CD81 Protein, Mouse (HEK293, His) CD81 antigen; CD81; CVID6; TAPA-1; TSPAN28	Mouse	HEK293
	The CD81 protein has important effects on cellular processes and is involved in CD19 receptor trafficking on activated B cells. This facilitates CD19-CR2 and B cell receptor complex assembly, lowering the antigen dose threshold for B cell clonal expansion. CD81 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD81 protein, expressed by HEK293 , with N-His labeled tag.

HY-P74263

	CD81 Protein, Mouse (HEK293, Fc) CD81 antigen; CD81; CVID6; TAPA-1; TSPAN28	Mouse	HEK293
	The CD81 protein has important effects on cellular processes and is involved in CD19 receptor trafficking on activated B cells. This facilitates CD19-CR2 and B cell receptor complex assembly, lowering the antigen dose threshold for B cell clonal expansion. CD81 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CD81 protein, expressed by HEK293 , with N-mFc labeled tag.

HY-P75378

	CD81 Protein, Rat (HEK293, Fc) CD81 antigen; CD81; CVID6; TAPA-1; TSPAN28	Rat	HEK293
	CD81, a versatile protein, participates in complement-opsonized particle ingestion, inhibits osteoclast formation, and regulates compartmentalized enzymatic activities. In T cells, CD81 controls intracellular dNTP levels by localizing and degrading SAMHD1. Moreover, it influences cell adhesion and motility, notably in macrophages. CD81 Protein, Rat (HEK293, Fc) is the recombinant rat-derived CD81 protein, expressed by HEK293 , with N-mFc labeled tag.

HY-P76244

	CD81 Protein, Cynomolgus/Rhesus Macaque (HEK293, His) CD81 antigen; CD81; CVID6; TAPA-1; TSPAN28	Rhesus Macaque/Cynomolgus	HEK293
	The CD81 protein is a member of the growth hormone/prolactin family and regulates a variety of physiological processes. Prolactin is mainly associated with mammary gland development and lactation, has pleiotropic effects, and affects immune responses, metabolism, and behavior. CD81 Protein, Cynomolgus/Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived CD81 protein, expressed by HEK293 , with N-His labeled tag.

HY-P72706

	CD81 Protein, Human (HEK293, Fc) CD81 antigen; CD81 molecule; CD81; CVID6; TAPA1; TAPA-1; TSPAN28	Human	HEK293
	The CD19 receptor is critical for B cell activation, driving the trafficking and assembly of CD19-CR2 and BCR complexes, thereby lowering the antigenic threshold for B cell clonal expansion. In T cells, CD19 contributes to CD3 localization and influences polarization. CD81 Protein, Human (HEK293, Fc) is the recombinant human-derived CD81 protein, expressed by HEK293 , with N-hFc labeled tag.

HY-P72126

	CD81 Protein, Human (His-SUMO) 26 kDa cell surface protein TAPA 1; 26 kDa cell surface protein TAPA-1; 26 kDa cell surface protein TAPA1; CD 81; CD81; CD81 antigen target of antiproliferative 1; ; CD81 antigen; CD81 molecule; CD81_HUMAN; CVID6; S5.7; TAPA 1; TAPA1; Target of the antiproliferative 1; Tetraspanin 28; Tetraspanin-28; Tetraspanin28; Tspan 28; Tspan-28; Tspan28	Human	E. coli
	The CD19 receptor is critical for B cell activation, driving the trafficking and assembly of CD19-CR2 and BCR complexes, thereby lowering the antigenic threshold for B cell clonal expansion. In T cells, CD19 contributes to CD3 localization and influences polarization. CD81 Protein, Human (His-SUMO) is the recombinant human-derived CD81 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.

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Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
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Storage & Stability
Shipping
Free Sample	Yes No
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Host:	Mouse (3) Rabbit (3)
Reactivity:	Human (5) mouse (1) rat (1) Rat (3) Mouse (3)
Application:	IHC-P (5) ICC/IF (4) IF-Tissue (1) IP (1) IHC-F (2) WB (6) FC (3) ELISA (3)
Isotype:	IgG,Kappa (1) IgG (3) IgG1 (2)
Conjugation:	Non-conjugated (6)
Clonality:	Monoclonal (3) Recombinant (2)
Modification:	Unmodified (4)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P80608

	CD81 Antibody (YA525) 1 Publications Verification CD81; TAPA1; TSPAN28; CD81 antigen; 26 kDa cell surface protein TAPA-1; Target of the antiproliferative antibody 1; Tetraspanin-28; Tspan-28; CD81	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse
	CD81 Antibody (YA525) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD81.

HY-P87769

	CD81 Antibody (YA7454)	WB, IHC-P, ICC/IF, ELISA	Human, Mouse, Rat
	CD81 Antibody (YA7454) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to CD81.

HY-P810215

	CD81 Antibody (YA9559)	WB, ICC/IF, IF-Tissue, FC, IP	mouse, rat
	CD81 Antibody (YA9559) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to CD81.

HY-P80608A

	CD81 Antibody (YA525)(PBS only) CD81; TAPA1; TSPAN28; CD81 antigen; 26 kDa cell surface protein TAPA-1; Target of the antiproliferative antibody 1; Tetraspanin-28; Tspan-28; CD81	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse
	CD81 Antibody (YA525) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD81.

HY-P84416

	CD81 Antibody (YA4113) S5.7; CVID6; TAPA1; TSPAN28	WB, IHC-P, FC, ELISA	Human, Rat
	CD81 Antibody (YA4113) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD81.

HY-P84416A

	CD81 Antibody (YA4113)(PBS only) S5.7; CVID6; TAPA1; TSPAN28	WB, IHC-P, FC, ELISA	Human, Rat
	CD81 Antibody (YA4113) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD81.

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Products	In-stock - + Add to Cart
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Cat. No.	Product Name		Classification

HY-RS17125

Cd81 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Cd81 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cd81 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-142989

1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine		Phospholipids
1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine is a polyunsaturated phospholipid that serves as a component of lipid monolayers and small unilamellar vesicles. 1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine can be used to prepare endoplasmic reticulum-targeted liposomes (PERLs), which are composed of 1,2-didocosahexaenoyl-sn-glycero-3-phosphoethanolamine, l-α-phosphatidylinositol and l-α-phosphatidylserine at a molar ratio of 1.5:1.5:1:1. PERLs reduce cholesterol levels in human peripheral blood mononuclear cells (PBMCs) and decrease HIV-1 particle secretion from HIV-1-infected PBMCs. Liposomes formed from 1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine exhibit cytotoxicity against leukemia cells. 1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine is applicable to studies related to hepatitis C virus infection, HIV infection, hepatitis B virus infection and leukemia .

HY-RS02270

CD81 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
CD81 Human Pre-designed siRNA Set A contains three designed siRNAs for CD81 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS23570

Cd81 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Cd81 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cd81 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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CD81

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