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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
91 Results for "
CGI
" in MedChemExpress (MCE) Product Catalog:
Products (91)
91 Results for "CGI" in MCE Product Catalog:
9
9 Cited Publications
Research Areas:
CGI-1746 is a potent and highly selective inhibitor of the Btk with IC50 of 1.9 nM.
Cat. No.: HY-18016
CAS No.: 845269-74-1
Target:
Research Areas:
CGI 560 is an inhibitor for Bruton's tyrosine kinase (BTK) with an IC50 of 400 nM.
Cat. No.: HY-10845
CAS No.: 127692-13-1
CGI-17341 is a 5-nitroimidazole antibacterial agent that has the activity of inhibiting sensitive and multidrug-resistant strains of Mycobacterium tuberculosis in vitro and prolonging the survival time of mice infected with Mycobacterium tuberculosis in vivo in a dose-dependent manner.
Synonyms: Ro 13-6438; Ro 13-6438/006
Research Areas:
Quazinone is a selective inhibitor of cGMP-inhibited-phosphodiesterase (cGI-PDE, PDE3). Quazinone inhibits the phosphorylation of p42/p44 MAP kinase. Quazinone possesses antimitogenic effect .
Cat. No.: HY-165568
CAS No.: 76470-87-6
Target:
Research Areas:
OPC 3911 is a highly selective inhibitor of cGMP-inhibited cAMP phosphodiesterase (cGI-PDE/PDE3) and a vasodilator, with an IC50 of 0.042 μM against rat cGI-PDE. OPC 3911 upregulates the expression of Osteopontin. OPC 3911 mediates vasodilation of arterial smooth muscle, induces vasodilatory responses in isolated rat arteriovenous tissues, and exhibits additive vasodilatory effects with Isoprenaline (HY-108353) and Forskolin (HY-15371). OPC 3911 can be used in studies related to congestive heart failure and insulin resistance .
Cat. No.: HY-P84887A
Synonyms: CIA; CGI-98; HSPC146
Cat. No.: HY-P81363A
Synonyms: NCIE2; CGI-58; ABHD5; 1-acylglycerol-3-phosphate O-acyltransferase ABHD5; Abhydrolase domain-containing protein 5; Lipid droplet-binding protein CGI-58
Cat. No.: HY-P82817
Synonyms: CGI149; NEDF; VPS24; CGI-149; CHMP3; Charged multivesicular body protein 3; Chromatin-modifying protein 3; Neuroendocrine differentiation factor; Vacuolar protein sorting-associated protein 24; hVps24
Cat. No.: HY-P75961
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PDE3A; CGMP-Inhibited CAMP Phosphodiesterase; Phosphodiesterase 3A; Phosphodiesterase 3A, CGMP-Inhibited; CGI-PDE; CGI-PDE A; CGMP-Inhibited 3',5'-Cyclic Phosphodiesterase 3A; CAMP Phosphodiesterase, Myocardial CGMP-Inhibited; CGMP-Inhibited 3',5'-Cyclic
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P702199
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ADIPOR1; Progestin And AdipoQ Receptor Family Member I; Adiponectin Receptor 1; Adiponectin Receptor Protein 1; PAQR1; TESBP1A; ACDCR1; CGI-45; Progestin And AdipoQ Receptor Family Member 1; CGI45
Species:
Human
Source:
E. coli Cell-free
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
