Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
57 Results for "
CRF2
" in MedChemExpress (MCE) Product Catalog:
Products (57)
57 Results for "CRF2" in MCE Product Catalog:
4
Target:
Research Areas:
Antisauvagine-30 (aSvg-30) is a selective peptide antagonist of the CRF2 receptor, with an IC50 of 1.1 nM for mouse CRF2. Antisauvagine-30 modulates cAMP signaling, gastric emptying, food intake, fear conditioning, anxiety-like behavior, stress responses, corticosterone levels, c-Fos expression, and CRF expression. Antisauvagine-30 is used in studies of anxiety-related disorders [2] .
4
Target:
Research Areas:
Antisauvagine-30 TFA (aSvg-30 TFA) is a selective peptide antagonist of the CRF2 receptor, with an IC50 of 1.1 nM for mouse CRF2. Antisauvagine-30 TFA modulates cAMP signaling, gastric emptying, food intake, fear conditioning, anxiety-like behavior, stress responses, corticosterone levels, c-Fos expression, and CRF expression. Antisauvagine-30 TFA is used in studies of anxiety-related disorders [2] .
1
1 Cited Publications
Cat. No.: HY-P72599
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL10RB; CDW210B; Prev. D21S58; IL-10 Receptor Subunit Beta; Prev. D21S66; IL-10R Subunit Beta; Prev. CRFB4; IL-10R Subunit 2; IL-10R2; IL-10RB; CRF2-4; Cytokine Receptor Family II, Member 4; Interleukin-10 Receptor Subunit Beta; Cytokine Receptor Class-II
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P77969
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: IL22RA1; Interleukin 22 Receptor, Alpha 1; Prev. IL22R; IL-22R-Alpha-1; CRF2-9; IL-22RA1; Interleukin-22 Receptor Subunit Alpha-1; ZcytoR11; Cytokine Receptor Class-II Member 9; Interleukin 22 Receptor; Cytokine Receptor Family 2 Member 9; IL22R1; Interle
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P2847
CAS No.: 330648-32-3
Target:
Research Areas:
Cat. No.: HY-P1752
CAS No.: 351999-18-3
Synonyms: GSK561679
Target:
Research Areas:
Verucerfont is a corticotropin-releasing factor receptor 1 (CRF1) antagonist with IC50s of ~6.1, >1000 and >1000?nM for CRF1, CRF2, and CRF-BP, respectively.
Target:
Research Areas:
CP 154526 hydrochloride is a potent, brain-penetrant and selective corticotropin-releasing factor receptor 1 (CRF1) antagonist with a Ki of 2.7 nM. CP 154526 hydrochloride shows selective for CRF1 over CRF2 (Ki = >10 μM). CP 154526 hydrochloride has anxiolytic activities [2].
Cat. No.: HY-P1294
CAS No.: 90880-23-2
Target:
Research Areas:
Cat. No.: HY-P1106A
Target:
Research Areas:
Cat. No.: HY-P1294A
Target:
Research Areas:
Cat. No.: HY-P1752B
Cat. No.: HY-P1106
CAS No.: 434938-41-7
Target:
Research Areas:
Cat. No.: HY-P1296
CAS No.: 171543-83-2
Synonyms: Urocortin (Rattus norvegicus); Rat urocortin
Target:
Research Areas:
Cat. No.: HY-12130
CAS No.: 157286-86-7
Target:
Research Areas:
CP 154526 is a potent, brain-penetrant and selective corticotropin-releasing factor receptor 1 (CRF1) antagonist with a Ki of 2.7 nM. CP 154526 shows selective for CRF1 over CRF2 (Ki = >10 μM). CP 154526 has anxiolytic activities [2].
Cat. No.: HY-103378
CAS No.: 603151-83-3
Target:
Research Areas:
NBI 35965 methanesulfonate is a selective, orally active and brain-penetrant corticotropin-releasing factor receptor 1 (CRF1) antagonist with a Ki value of 4 nM and a pKi value of 8.5. NBI 35965 methanesulfonate does not inhibit CRF2. NBI 35965 methanesulfonate reduces CRF or stress-induced adrenocorticotropic hormone (ACTH) production in vivo with pIC50 values of 7.1 and 6.9, respectively. NBI 35965 methanesulfonate shows anxiolytic effects [2].
Cat. No.: HY-P1542
CAS No.: 83930-33-0
Synonyms: Catostomus urotensin I
Target:
Research Areas:
Cat. No.: HY-14128
CAS No.: 268545-87-5
Synonyms: SB-723620
Target:
Research Areas:
NBI-34041 (SB-723620) is a selective and orally active nonpeptide CRF1 receptor antagonist with an IC50 of 58.9 nM and a Ki of 4.0 nM for human CRF1 receptor. NBI-34041 has no inhibitory effect on the CRF2 receptor. NBI-34041 can be used for depression and anxiety disorders research.
Cat. No.: HY-P1542B
Synonyms: Catostomus urotensin I TFA
Target:
Research Areas:
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
