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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
Celastrol
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "Celastrol" in MCE Product Catalog:
66
66 Cited Publications
Synonyms: Tripterine; Tripterin
8
Category:
Triterpenes Terpenoids Celastraceae Plants Tripterygium wilfordii Hook. f. Disease Research Fields Cancer
Target:
Cat. No.: HY-13067R
CAS No.: 34157-83-0
Synonyms: Tripterine (Standard); Tripterin (Standard)
Synonyms: Celastrol-Biotin
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Biotin-Cel (Celastrol-Biotin) is a biotin-labeled Celastrol (HY-13067). Celastrol exhibits antitumor, anti-inflammatory, and anti-obesity activities. Biotin-Cel can be used in biotin-affinity pulldown assay to identify the molecular target of Celastrol in hepatocellular carcinoma cells .
Cat. No.: HY-13067G
CAS No.: 34157-83-0
Synonyms: Tripterine (GMP); Tripterin (GMP)
Cat. No.: HY-174412
CAS No.: 2027514-32-3
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LC-PDin06 is a selective PRDX1 inhibitor with an IC50 of 0.042 μM. LC-PDin06, a Celastrol (HY-13067) derivative, shows potent antiproliferative activity against colorectal cancer cells by significantly increasing ROS levels .
Cat. No.: HY-174347
CAS No.: 2758818-41-4
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Research Areas:
Hsp90-Cdc37-IN-4, a Celastrol (HY-13067) derivative, inhibits the Hsp90-Cdc37 protein-protein interaction (PPI). Hsp90-Cdc37-IN-4 selectively inhibits casein kinase 2 (CK2), reducing phosphorylation of its substrate Cdc37 at Serine 13. Hsp90-Cdc37-IN-4 induces G0/G1 cell cycle arrest and triggers apoptosis via the mitochondrial pathway. Hsp90-Cdc37-IN-4 demonstrates potent anti-breast cancer activity .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
