16 Results for "

Chrysin

" in MedChemExpress (MCE) Product Catalog:
Products (16)

16 Results for "Chrysin" in MCE Product Catalog:

16
16 Cited Publications
Cat. No.: HY-14589
CAS No.: 480-40-0
Purity:  99.85%
Synonyms: 5,7-Dihydroxyflavone
Chrysin is one of the most well known estrogen blockers.
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1 Cited Publications
Cat. No.: HY-N2376
CAS No.: 35775-49-6
Chrysin-7-O-glucuronide is a flavonoid found in Scutellaria baicalensis. Chrysin-7-O-glucuronide inhibits α-glucosidase and α-amylase with IC50 values of 612.13 and 980.73 μg/mL. Chrysin-7-O-glucuronide suppresses NF-κB signaling activity. Chrysin-7-O-glucuronide scavenges free radicals, acts as a tight junction protector, and mitigates intestinal mucosal barrier injury. Chrysin-7-O-glucuronide can be used for the research of type 2 diabetes and severe acute pancreatitis-induced intestinal mucosal barrier injury .
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Cat. No.: HY-160250
CAS No.: 2097024-37-6
Target:  

Fluorescent Dye UGT

Research Areas:  

Metabolic Disease

UGT1A1-IN-1 is a UGT1A1 inhibitor and fluorescent probe (Ex=370 nm, Em=520 nm), with an IC50 of 1.33 μM and a Ki of 5.02 μM. UGT1A1-IN-1 is selectively glucuronidated by UGT1A1 at the bilirubin homologous binding site, and its PET effect is blocked along with this reaction, triggering fluorescence changes. UGT1A1-IN-1 can serve as a substitute for bilirubin to detect UGT1A1 activity and perform high-throughput screening of UGT1A1 modulators .
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Cat. No.: HY-14589R
CAS No.: 480-40-0
Synonyms: 5,7-Dihydroxyflavone (Standard)
Chrysin (Standard) is the analytical standard of Chrysin. This product is intended for research and analytical applications. Chrysin is one of the most well known estrogen blockers.
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Cat. No.: HY-120294
CAS No.: 185145-34-0
Purity:  99.11%
Chrysin 6-C-glucoside 8-C-arabinoside can inhibit the CGRP releasing and the activation of TRPV1 channel. Chrysin 6-C-glucoside 8-C-arabinoside can be used for anti-migraine research .
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Cat. No.: HY-129131
CAS No.: 185145-33-9
Chrysin 6-C-arabinoside 8-C-glucoside is a α±-glucosidase inhibitors which are widely used in the study for type 2 diabetes .
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Cat. No.: HY-125849
CAS No.: 88640-89-5
Synonyms: Chrysin 7-O-β-gentiobioside
Chrysin 7-O-beta-gentiobioside (Chrysin 7-O-β-gentiobioside) is the glycosylation product of Chrysin .
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Cat. No.: HY-N2376R
CAS No.: 35775-49-6
Chrysin-7-O-glucuronide (Standard) is the analytical standard of Chrysin-7-O-glucuronide (Hy-N2376). This product is intended for research and analytical applications. Chrysin-7-O-glucuronide is a flavonoid found in Scutellaria baicalensis. Chrysin-7-O-glucuronide inhibits α-glucosidase and α-amylase with IC50 values of 612.13 and 980.73 μg/mL. Chrysin-7-O-glucuronide suppresses NF-κB signaling activity. Chrysin-7-O-glucuronide scavenges free radicals, acts as a tight junction protector, and mitigates intestinal mucosal barrier injury. Chrysin-7-O-glucuronide can be used for the research of type 2 diabetes and severe acute pancreatitis-induced intestinal mucosal barrier injury .
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Cat. No.: HY-N13388
CAS No.: 27939-38-4
Synonyms: UGT1A6
5-Hydroxytryptophol-O-glucuronide (UGT1A6) is an authentic glucuronide standard and probe metabolite. 5-Hydroxytryptophol-O-glucuronide is used to detect the activity of human UGT1A6 in in vitro systems including human liver microsomes and recombinant UGT1A6 .
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Cat. No.: HY-N8639
CAS No.: 160880-89-7
Chrysin 8-C-β-D-glucoside is a natural compound isolated from the herbs of Psidium guajava .
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Cat. No.: HY-167770
CAS No.: 863992-13-6
Target:  

Drug Metabolite

Research Areas:  

Metabolic Disease

Chrysin 7-sulfate is a conjugated metabolite of Chrysin (HY-14589). Chrysin 7-sulfate can strongly displace the Site I marker warfarin from human serum albumin. Chrysin 7-sulfate can effectively displace Ochratoxin A (OTA) (HY-N6788) from albumin both in vitro and in vivo .
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Cat. No.: HY-161757
Target:  

Drug Derivative

Research Areas:  

Inflammation/Immunology

Anti-inflammatory agent 86 is a Chrysin (HY-14589) derivative with anti-inflammatory effects. Anti-inflammatory agent 86 inhibits monocyte adhesion to colon epithelium induced by TNF-α, with an IC50 of 4.71 μM. Anti-inflammatory agent 86 has the potential for the inflammatory bowel disease (IBD) research .
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Cat. No.: HY-172175
Research Areas:  

Cancer

HYS-072 is an orally active derivative of chrysin (HY-14589) with antitumor activity. HYS-072 induces apoptosis and autophagy by inhibiting the PI3K/AKT/mTOR signaling pathway and suppresses tumor growth in vivo in xenograft models by modulating autophagy-related pathways. HYS-072 can be used in the research of triple-negative breast cancer .
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Cat. No.: HY-N13552
CAS No.: 35775-46-3
Chrysin7-O-neohesperidoside is a flavonoid product that can be isolated from Cyclanthera pedata Schrad. .
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Cat. No.: HY-144392
CAS No.: 84212-49-7
AChE/BuChE-IN-1 (Compound 1), a chrysin derivative, is a selective butyrylcholinesterase (BuChE) inhibitor with an IC50 of 0.48 μM. AChE/BuChE-IN-1 inhibits acetylcholinesterase (AChE) with an IC50 of 7.16 μM. AChE/BuChE-IN-1 shows strong scavenging ·OH activities with a IC50 of 0.1674 μM. AChE/BuChE-IN-1 inhibits reactive oxygen species (ROS), Aβ1-42 aggregation (self-, Cu2+-induced, AChE-induced). AChE/BuChE-IN-1 has high BBB permeability and bioavailability and low cell toxicity. AChE/BuChE-IN-1 has the potential for Alzheimer' disease (AD) research .
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Cat. No.: HY-N20679
CAS No.: 31025-53-3
Synonyms: Chrysin 7-β--D-glucoside
Aequinetin is a tyrosinase inhibitor, and docking results show that it forms hydrogen bonds and hydrophobic interactions with key protein residues of NF-κB p65, MAPK10 and ERK1 .
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