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Results for "

Chrysin

" in MedChemExpress (MCE) Product Catalog:

16

Inhibitors & Agonists

11

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-14589
    Chrysin
    10+ Cited Publications

    5,7-Dihydroxyflavone

    		 Estrogen Receptor/ERR Cancer
    Chrysin is one of the most well known estrogen blockers.
    Chrysin
  • HY-N2376
    Chrysin-7-O-glucuronide
    1 Publications Verification

    		 Glycosidase Amylases NF-κB Metabolic Disease Inflammation/Immunology
    Chrysin-7-O-glucuronide is a flavonoid found in Scutellaria baicalensis. Chrysin-7-O-glucuronide inhibits α-glucosidase and α-amylase with IC50 values of 612.13 and 980.73 μg/mL. Chrysin-7-O-glucuronide suppresses NF-κB signaling activity. Chrysin-7-O-glucuronide scavenges free radicals, acts as a tight junction protector, and mitigates intestinal mucosal barrier injury. Chrysin-7-O-glucuronide can be used for the research of type 2 diabetes and severe acute pancreatitis-induced intestinal mucosal barrier injury .
    Chrysin-7-O-glucuronide
  • HY-160250
    UGT1A1-IN-1

    		Fluorescent Dye UGT Metabolic Disease
    UGT1A1-IN-1 is a UGT1A1 inhibitor and fluorescent probe (Ex=370 nm, Em=520 nm), with an IC50 of 1.33 μM and a Ki of 5.02 μM. UGT1A1-IN-1 is selectively glucuronidated by UGT1A1 at the bilirubin homologous binding site, and its PET effect is blocked along with this reaction, triggering fluorescence changes. UGT1A1-IN-1 can serve as a substitute for bilirubin to detect UGT1A1 activity and perform high-throughput screening of UGT1A1 modulators .
    UGT1A1-IN-1
  • HY-14589R
    Chrysin (Standard)

    5,7-Dihydroxyflavone (Standard)

    		 Reference Standards Estrogen Receptor/ERR Cancer
    Chrysin (Standard) is the analytical standard of Chrysin. This product is intended for research and analytical applications. Chrysin is one of the most well known estrogen blockers.
    Chrysin (Standard)
  • HY-120294
    Chrysin 6-C-glucoside 8-C-arabinoside

    		CGRP Receptor TRP Channel Neurological Disease
    Chrysin 6-C-glucoside 8-C-arabinoside can inhibit the CGRP releasing and the activation of TRPV1 channel. Chrysin 6-C-glucoside 8-C-arabinoside can be used for anti-migraine research .
    Chrysin 6-C-glucoside 8-C-arabinoside
  • HY-129131
    Chrysin 6-C-arabinoside 8-C-glucoside

    		Glycosidase Metabolic Disease
    Chrysin 6-C-arabinoside 8-C-glucoside is a α±-glucosidase inhibitors which are widely used in the study for type 2 diabetes .
    Chrysin 6-C-arabinoside 8-C-glucoside
  • HY-125849
    Chrysin 7-O-beta-gentiobioside

    Chrysin 7-O-β-gentiobioside

    		 Drug Derivative Cancer
    Chrysin 7-O-beta-gentiobioside (Chrysin 7-O-β-gentiobioside) is the glycosylation product of Chrysin .
    Chrysin 7-O-beta-gentiobioside
  • HY-N2376R
    Chrysin-7-O-glucuronide (Standard)

    		Reference Standards Glycosidase Amylases NF-κB Metabolic Disease Inflammation/Immunology
    Chrysin-7-O-glucuronide (Standard) is the analytical standard of Chrysin-7-O-glucuronide (Hy-N2376). This product is intended for research and analytical applications. Chrysin-7-O-glucuronide is a flavonoid found in Scutellaria baicalensis. Chrysin-7-O-glucuronide inhibits α-glucosidase and α-amylase with IC50 values of 612.13 and 980.73 μg/mL. Chrysin-7-O-glucuronide suppresses NF-κB signaling activity. Chrysin-7-O-glucuronide scavenges free radicals, acts as a tight junction protector, and mitigates intestinal mucosal barrier injury. Chrysin-7-O-glucuronide can be used for the research of type 2 diabetes and severe acute pancreatitis-induced intestinal mucosal barrier injury .
    Chrysin-7-O-glucuronide (Standard)
  • HY-N13388
    5-Hydroxytryptophol-O-glucuronide

    UGT1A6

    		 Biochemical Assay Reagents Others
    5-Hydroxytryptophol-O-glucuronide is an authentic glucuronide standard and probe metabolite. 5-Hydroxytryptophol-O-glucuronide is used to detect the activity of human UGT1A6 in in vitro systems including human liver microsomes and recombinant UGT1A6 .
    5-Hydroxytryptophol-O-glucuronide
  • HY-N8684
    Chrysin 6-C-glucoside

    		Others Cancer
    Chrysin 6-C-glucoside (compound 14) is an active product that can be extrated from Psidium guajava. Chrysin 6-C-glucoside has anti-tumor effect .
    Chrysin 6-C-glucoside
  • HY-N8639
    Chrysin 8-C-β-D-glucoside

    		Others Others
    Chrysin 8-C-β-D-glucoside is a natural compound isolated from the herbs of Psidium guajava .
    Chrysin 8-C-β-D-glucoside
  • HY-167770
    Chrysin 7-sulfate

    		Drug Metabolite Metabolic Disease
    Chrysin 7-sulfate is a conjugated metabolite of Chrysin (HY-14589). Chrysin 7-sulfate can strongly displace the Site I marker warfarin from human serum albumin. Chrysin 7-sulfate can effectively displace Ochratoxin A (OTA) (HY-N6788) from albumin both in vitro and in vivo .
    Chrysin 7-sulfate
  • HY-161757
    Anti-inflammatory agent 86

    		Drug Derivative Inflammation/Immunology
    Anti-inflammatory agent 86 is a Chrysin (HY-14589) derivative with anti-inflammatory effects. Anti-inflammatory agent 86 inhibits monocyte adhesion to colon epithelium induced by TNF-α, with an IC50 of 4.71 μM. Anti-inflammatory agent 86 has the potential for the inflammatory bowel disease (IBD) research .
    Anti-inflammatory agent 86
  • HY-172175
    HYS-072

    		mTOR Akt PI3K Apoptosis Autophagy Cancer
    HYS-072 is an orally active derivative of chrysin (HY-14589) with antitumor activity. HYS-072 induces apoptosis and autophagy by inhibiting the PI3K/AKT/mTOR signaling pathway and suppresses tumor growth in vivo in xenograft models by modulating autophagy-related pathways. HYS-072 can be used in the research of triple-negative breast cancer .
    HYS-072
  • HY-N13552
    Chrysin7-O-neohesperidoside

    		Others Others
    Chrysin7-O-neohesperidoside is a flavonoid product that can be isolated from Cyclanthera pedata Schrad. .
    Chrysin7-O-neohesperidoside
  • HY-144392
    AChE/BuChE-IN-1

    		Cholinesterase (ChE) Neurological Disease
    AChE/BuChE-IN-1 (Compound 1), a chrysin derivative, is a selective butyrylcholinesterase (BuChE) inhibitor with an IC50 of 0.48 μM. AChE/BuChE-IN-1 inhibits acetylcholinesterase (AChE) with an IC50 of 7.16 μM. AChE/BuChE-IN-1 shows strong scavenging ·OH activities with a IC50 of 0.1674 μM. AChE/BuChE-IN-1 inhibits reactive oxygen species (ROS), Aβ1-42 aggregation (self-, Cu2+-induced, AChE-induced). AChE/BuChE-IN-1 has high BBB permeability and bioavailability and low cell toxicity. AChE/BuChE-IN-1 has the potential for Alzheimer' disease (AD) research .
    AChE/BuChE-IN-1

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