14 Results for "

DKK3

" in MedChemExpress (MCE) Product Catalog:
Products (14)

14 Results for "DKK3" in MCE Product Catalog:

Cat. No.: HY-P990250

Target:  

Wnt

Research Areas:  

Inflammation/Immunology

Anti-Mouse DKK3 Antibody (DKK3-4.22) is an anti-mouse DKK3 IgG1 monoclonal antibody. Anti-Mouse DKK3 Antibody (DKK3-4.22) can improve kidney function and increases T cell infiltration. Anti-Mouse DKK3 Antibody (DKK3-4.22) can reduce skin inflammation by blocking the immunosuppressive function of DKK3. Anti-Mouse DKK3 Antibody (DKK3-4.22) can be used for researches on inflammation conditions such as unilateral ureteral obstruction (UUO) and experimental autoimmune encephalomyelitis (EAE) .
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Cat. No.: HY-W107409
CAS No.: 213473-00-8
Meridianin C is a marine natural product with anticancer activity. Meridianin C has significant inhibitory effects on four different human tongue cancer cells (YD-8, YD-10B, YD-38 and HSC-3). Meridianin C most strongly reduced the growth of YD-10B cells, the most aggressive and tumorigenic of the cell lines tested. Meridianin C also induced significant accumulation of large vesicles in YD-10B cells, validating its function through macrophagocytosis. Meridianin C reduces cellular levels of Dickkopf-related protein-3 (DKK-3), a known negative regulator of macrophagy. Meridianin C affects macrophagocytosis by downregulating DKK-3, thereby affecting cell proliferation .
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Cat. No.: HY-RS16965
Research Areas:  

Others

Dkk3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Dkk3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS03789
Research Areas:  

Others

DKK3 Human Pre-designed siRNA Set A contains three designed siRNAs for DKK3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS23408
Research Areas:  

Others

Dkk3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Dkk3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-179459
CAS No.: 1210357-06-4
Target:  

Wnt LDLR Amyloid-β

Research Areas:  

Neurological Disease

SJ-300 is a potent and selective, orally active and brain-penetrat DKK3-LRP1 interaction inhibitor. SJ-300 restores Aβ clearance in AD models. SJ 300 binds to mLRPIV with a Kd of 7.9 μM, inhibits the DKK3 mLRPIV complex with an IC50 of 3.2 μM, and does not disrupt the binding of Aβ to LRP1. SJ 300 rescues cognitive function and ameliorates neuropathology (Aβ plaque reduction ≈ 73.3 %) in vivo. SJ 300 can be employed for research in Alzheimer’s disease .
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Cat. No.: HY-P85123
Synonyms: DKK3; REIC; Dickkopf-related protein 3; Dickkopf-3; DKK-3; hDKK-3

Host:  

Mouse

Application:  

WB, FC, ELISA

Reactivity:  

Human, Monkey

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Cat. No.: HY-P82106
Synonyms: DKK3; REIC; Dickkopf-related protein 3; Dickkopf-3; DKK-3; hDKK-3

Host:  

Rabbit

Application:  

WB, ICC/IF, IP

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P7812
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DKK3; HDKK-3; Dickkopf Wnt Signaling Pathway Inhibitor 3; DKK-3; REIC; Dickkopf WNT Signaling Pathway Inhibitor 3; Dickkopf-Related Protein 3; Dickkopf (Xenopus Laevis) Homolog 3; CRRL; Dickkopf 3 Homolog (Xenopus Laevis); RIG; Dickkopf 3 Homolog; Cardiom
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P75287
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DKK3; HDKK-3; Dickkopf Wnt Signaling Pathway Inhibitor 3; DKK-3; REIC; Dickkopf WNT Signaling Pathway Inhibitor 3; Dickkopf-Related Protein 3; Dickkopf (Xenopus Laevis) Homolog 3; CRRL; Dickkopf 3 Homolog (Xenopus Laevis); RIG; Dickkopf 3 Homolog; Cardiom
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P78681
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DKK3; HDKK-3; Dickkopf Wnt Signaling Pathway Inhibitor 3; DKK-3; REIC; Dickkopf WNT Signaling Pathway Inhibitor 3; Dickkopf-Related Protein 3; Dickkopf (Xenopus Laevis) Homolog 3; CRRL; Dickkopf 3 Homolog (Xenopus Laevis); RIG; Dickkopf 3 Homolog; Cardiom
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P84857
Synonyms: RIG; REIC

Host:  

Mouse

Application:  

WB, IHC-P, FC, ELISA

Reactivity:  

Human, Mouse, Rat, Rabbit, Monkey

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Cat. No.: HY-P77640
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: DKK3; HDKK-3; Dickkopf Wnt Signaling Pathway Inhibitor 3; DKK-3; REIC; Dickkopf WNT Signaling Pathway Inhibitor 3; Dickkopf-Related Protein 3; Dickkopf (Xenopus Laevis) Homolog 3; CRRL; Dickkopf 3 Homolog (Xenopus Laevis); RIG; Dickkopf 3 Homolog; Cardiom
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P84857A
Synonyms: RIG; REIC

Host:  

Mouse

Application:  

WB, IHC-P, FC, ELISA

Reactivity:  

Human, Mouse, Rat, Rabbit, Monkey

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