173 Results for "

Diethyl

" in MedChemExpress (MCE) Product Catalog:
Products (173)

173 Results for "Diethyl" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-Y0836
CAS No.: 123-25-1
Synonyms: Diethyl Butanedioate
Diethyl succinate (Diethyl Butanedioate) can be utilized at physiological pH, allowing it to penetrate biological membranes and integrate into the cells of tissue cultures, where it is metabolized via the tricarboxylic acid cycle. Diethyl succinate modulates the polarization and activation of microglial cells by reducing mitochondrial fission and the levels of reactive oxygen species (ROS), thereby exerting an inflammatory protective effect in primary microglial cells. Furthermore, Diethyl succinate is non-toxic and can be used in flavorings and seasonings .
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4
4 Cited Publications
Cat. No.: HY-103068
CAS No.: 1821370-70-0
Purity:  99.90%
Target:  

MMP

Research Areas:  

Cancer

Diethyl-pythiDC is an inhibitor of collagen prolyl 4-hydroxylases (CP4Hs).
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2
2 Cited Publications
Cat. No.: HY-Y0284
CAS No.: 84-66-2
Diethyl phthalate is an orally active plasticizer and detergent base. Diethyl phthalate increases the activities of ACP, ALP, SDH, and ALT in liver, muscle, or both tissues. Diethyl phthalate induces dose-dependent mortality and sluggish behavior in freshwater fish. Diethyl phthalate may induce male reproductive toxicity. Diethyl phthalate is added to plastic polymers to help maintain their flexibility .
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1
1 Cited Publications
Cat. No.: HY-Y1147
CAS No.: 141-05-9
Synonyms: Maleic acid Diethyl ester
Diethyl maleate (DEM) is an orally available, effective glutathione (GSH) depletor that crosses the blood-brain barrier. Diethyl maleate covalently binds irreversibly to GSH via glutathione S-transferase with an in vitro IC50 of 0.1-0.5 mM. Diethyl maleate selectively depletes GSH in liver, lung, and brain tissues, exacerbating oxidative stress and enhancing hyperbaric oxygen toxicity. Diethyl maleate promotes precursor amino acid uptake and in turn promotes GSH synthesis by upregulating the activity of the cystine-glutamate transporter XO -. Diethyl maleate can be used to study redox homeostasis and GSH protection mechanisms in oxidative stress-related diseases such as hyperbaric oxygen injury and metabolic diseases[1][2][3].
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1
1 Cited Publications
Cat. No.: HY-107740
CAS No.: 977-96-8
Purity:  99.85%
Synonyms: 1,1'-Diethyl-2,2'-cyanine iodide; Decynium 22; Diethylcyanine iodide; Eastman 7851
Pseudoisocyanine iodide (1,1'-Diethyl-2,2'-cyanine iodide) is an inhibitor of organic cation transporters (OCT1, OCT2, OCT3) and plasma membrane monoamine transporter (PMAT). Pseudoisocyanine iodide has antidepressant activity .
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1
1 Cited Publications
Cat. No.: HY-W010056
CAS No.: 623-91-6
Diethyl fumarate is a Nrf2 inducer. Diethyl fumarate induces non-immunological contact urticaria, causing erythema, edema, and dose-dependent skin responses characterized by rapid onset, peak response, and subsequent resolution. The hybrid of Diethyl fumarate and Curcumin (HY-N0005) exerts neuroprotective effects. Diethyl fumarate can be used in the research of Parkinson's disease and non-immunological contact urticaria .
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1
1 Cited Publications
Cat. No.: HY-44178
CAS No.: 133-08-4
Diethyl butylmalonate is a competitive inhibitor of succinate dehydrogenase. Diethyl butylmalonate exerts anti-inflammatory effects by inhibiting ROS production. Diethyl butylmalonate also has neuroprotective activity. In addition, Diethyl butylmalonate shows toxicity to T. pyriformis, with its log(IGC50 -1) being 0.557. Diethyl butylmalonate can be used in the research of diseases such as Alzheimer's disease .
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Cat. No.: HY-D0846
CAS No.: 1609-47-8
Diethyl pyrocarbonate is a potent, orally active, non-specific chemical inhibitor of RNase. Diethyl pyrocarbonate has been useful in vitro as an agent relatively specific for binding to imidazole of histidine. Diethyl pyrocarbonate inhibits central chemosensitivity in rabbits. Diethyl pyrocarbonate can modify Ser, Thr, His and Tyr residues. Diethyl pyrocarbonate can be used for modeling .
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Cat. No.: HY-B0978
CAS No.: 134-62-3
Synonyms: DEET; N,N-Diethyl-m-toluamide
Diethyltoluamide (DEET) is the most common active ingredient in insect repellents. It is intended to provide protection against mosquitoes, ticks, fleas, chiggers, leeches, and many other biting insects. Diethyltoluamide is toxic to hepatocytes and can lead to many physiological, pharmacological, and behavioral abnormalities, particularly motor deficits and learning and memory dysfunction .
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Cat. No.: HY-Y0190
CAS No.: 87-91-2
Synonyms: Diethyl tartrate
(2R,3R)-Diethyl 2,3-dihydroxysuccinate (Diethyl tartrate) is utilized in food industry as a flavoring agent and acidity regulator and for this purpose is also used in wines .
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Cat. No.: HY-101417
CAS No.: 598-02-7
Purity:  ≥98.0%
Synonyms: Diethyl phosphoric acid
Diethylphosphate (Diethyl phosphoric acid) is an orally active organophosphorus pesticides metabolite. Diethylphosphate can interfere with thyroid hormone-related mechanisms and affect intestinal microbes in rats .
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Cat. No.: HY-112106A
CAS No.: 220439-24-7
Purity:  99.87%
Synonyms: DA-6 citrate; 2-Diethylaminoethyl hexanoate citrate
Research Areas:  

Others

Diethyl aminoethyl hexanoate citrate is a compound that is widely used as a plant growth regulator.
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Cat. No.: HY-118594
CAS No.: 632-93-9
Purity:  99.79%
Target:  

Ferrochelatase

Research Areas:  

Metabolic Disease

Diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate is an orally active porphyrin inducer and ferrochelatase inhibitor. Diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate can induce small bile duct obstruction in mice, resulting in blocked bile excretion and causing cholestasis. Long-term use of Diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate can cause damage to bile duct epithelial cells, inflammatory responses, and liver fibrosis. Diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate can be used to simulate the pathological features of cholestatic liver diseases such as sclerosing cholangitis (PSC) .
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Cat. No.: HY-136376
CAS No.: 135590-91-9
Purity:  99.45%
Research Areas:  

Others

Mefenpyr-diethyl is a pyrazoline-type herbicide safener that functions to enhance lipid biosynthesis. Mefenpyr-diethyl effectively prevents herbicide-induced phytotoxic damage caused by herbicides such as fenoxaprop-p-ethyl (HY-B2013) and mesosulfuron-methyl (HY-126987) by protecting cereal crops including wheat. Mefenpyr-diethyl significantly increases lipid content in wheat either when applied alone or in combination with the herbicide fenoxaprop-p-ethyl. The mechanism of action of Mefenpyr-diethyl does not involve the induction of glutathione S-transferase (GST) activity in wheat .
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Cat. No.: HY-Y0836S
CAS No.: 1628796-56-4
Synonyms: 1,4-Diethyl butanedioate-1,2,3,4-13C4
Diethyl succinate- 13C4 is the 13C labeled Diethyl succinate . Diethyl succinate (Diethyl Butanedioate) is used at physiological pH and crosses biological membranes, incorporates into cells in tissue culture and is metabolized by the TCA cycle. Diethyl succinate is known to be non-toxic and used in fragrances and flavoring .
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Cat. No.: HY-76459
CAS No.: 2537-48-6
Diethyl (cyanomethyl)phosphonate is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Diethyl (cyanomethyl)phosphonate is also an important intermediate and can be used in the synthesis of other active compounds .
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Cat. No.: HY-Y1361
CAS No.: 13811-71-7
Synonyms: D-(-)-Tartaric acid Diethyl ester
Diethyl D-(-)-tartrate (D-(-)-Tartaric acid diethyl ester) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Diethyl D(-)-tartrate can also react with fatty carbonyl compounds to form bis(sodium carboxylate) types of surfactants, which have good water solubility, strong ability to lower surface tension, and can be easily decomposed under acidic conditions .
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Cat. No.: HY-I1162
CAS No.: 1068-90-2
Synonyms: Diethyl 2-acetamidomalonate
Diethyl 2-acetamidomalonate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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Cat. No.: HY-29262
CAS No.: 7209-00-9
Target:  

Drug Intermediate

Research Areas:  

Others

Diethyl 2-bromoglutarate is a drug intermediate for synthesis of various active compounds.
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Cat. No.: HY-116893
CAS No.: 1762-46-5
Purity:  98.79%
Research Areas:  

Cancer

Diethyl bipy55'DC is an inhibitor of collagen proline 4-hydroxylases (CP4Hs) with antifibrotic and anti-metastatic activities. Diethyl bipy55'DC can inhibit CP4H activity in cultured cells at concentrations that do not cause iron deficiency .
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