41 Results for "

EDA

" in MedChemExpress (MCE) Product Catalog:
Products (41)

41 Results for "EDA" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P75262
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Tumor necrosis factor receptor superfamily member EDAR; EDA-A1 receptor; EDAR
Species:  
Source:  
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Cat. No.: HY-126688
CAS No.: 2259318-53-9
Purity:  93.43%
Research Areas:  

Cancer

Mal-C2-Gly3-EDA-PNU-159682, a agent-linker conjugate for ADC, consists a cleavable ADC linker Mal-C2-Gly3-EDA and a potent ADC cytotoxin PNU-159682.
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Cat. No.: HY-N2587
CAS No.: 548-76-5
Irigenin is a is a lead compound, and mediates its anti-metastatic effect by specifically and selectively blocking α9β1 and α4β1 integrins binding sites on C-C loop of Extra Domain A (EDA). Irigenin shows anti-cancer properties. It sensitizes TRAIL-induced apoptosis via enhancing pro-apoptotic molecules in gastric cancer cells .
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Cat. No.: HY-130893
CAS No.: 111790-37-5
Purity:  97.49%
Target:  

PROTAC Linkers

Research Areas:  

Cancer

Biotin-EDA is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
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Cat. No.: HY-D1603
CAS No.: 209541-26-4
BODIPY FL-EDA is a widely used fluorescent dye for quantitative analysis of nucleotides. BODIPY FL-EDA is an aliphatic amine analog that can react with aldehydes and ketones. BODIPY FL-EDA can be used to detect both modified and unmodified deoxynucleotides and to determine DNA damage and genomic DNA methylation through capillary electrophoresis with laser-induced fluorescence (CE-LIF). Additionally, it can be used for quantifying intracellular ATP levels. The excitation wavelength is 500 nm, and the emission wavelength is 510 nm .
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Cat. No.: HY-145078
CAS No.: 1957223-28-7
Research Areas:  

Cancer

PNU-EDA-Gly5 is an oligo-glycine linker-payload for ADC synthesis, composed of a DNA topoisomerase I inhibitor PNU-159682 and a linker EDA-Gly5 .
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Cat. No.: HY-147097A
CAS No.: 87156-01-2
Purity:  ≥95.0%
Target:  

Bacterial

Research Areas:  

Infection

EDA-DA is a N-terminally tagged dipeptide probe, can be used to label Peptidoglycan (PG) of bacteria. EDA-DA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups .
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Cat. No.: HY-171489
CAS No.: 2028299-61-6
Research Areas:  

Cancer

Mal-VC-PAB-EDA-N-Ac-Calicheamicin is a Drug-Linker Conjugate for ADC with potent antitumor activity. Mal-VC-PAB-EDA-N-Ac-Calicheamicin consists of ADC toxin Calicheamicin (HY-19609) and a linker. Mal-VC-PAB-EDA-N-Ac-Calicheamicin can be used for synthesis of ADC, PF-06647263 (HY-111965) .
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Cat. No.: HY-151829
CAS No.: 2616562-74-2
Target:  

ADC Linkers

Research Areas:  

Others

Fmoc-L-Asn(EDA-N3)-OH is a click chemistry reagent containing an azide group. This building block is reported in literature for the modification of Amanitin via Click Chemistry. Alpha-Amanitin is the deadliest member of the amatoxin peptide family produced by the death-cap mushroom A. phalloides. It is an orally available, rigid, bicyclic octapeptide and one of the most lethal known natural products (LD50 = 50-100 μg/kg) acting as highly selective allosteric inhibitor of the RNA polymerase II . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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Cat. No.: HY-D1395
Research Areas:  

Others

RH-EDA is a rhodamine-based turn-on fluorescent probe for detecting hydroxyl radicals in living systems.
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Cat. No.: HY-151842
CAS No.: 432507-62-5
Target:  

ADC Linkers

Research Areas:  

Others

Fmoc-EDA-N3 is a click chemistry reagent containing an azide group . Fmoc-EDA-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Cat. No.: HY-126673
CAS No.: 2741725-04-0
Target:  

ADC Linkers

Research Areas:  

Cancer

Mal-C2-Gly3-EDA is a cleavable ADC linker containing a Maleimide group. Mal-C2-Gly3-EDA is used for making antibody-drug conjugate.
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Cat. No.: HY-147097
CAS No.: 87156-00-1
Target:  

Bacterial

Research Areas:  

Infection

EDA-DA, a N-terminally tagged dipeptide probe, can be used to label Peptidoglycan (PG) of bacteria. Peptidoglycan (PG), an essential structure in the cell walls of the vast majority of bacteria, is critical for division and maintaining cell shape and hydrostatic pressure . EDA-DA is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Cat. No.: HY-125810
CAS No.: 306305-07-7
4'-Ethynyl-2'-deoxyadenosine (4'-E-dA), a nucleoside reverse transcriptase (RT) inhibitor, is an antiretroviral agent which is potent against drug-resistant HIV variants, with an EC50 of 98 nM in MT-4 cells for anti-HIV-1 activity . 4'-Ethynyl-2'-deoxyadenosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Cat. No.: HY-114346A
CAS No.: 220524-70-9
ODIPY FL EDA free base is an amine-based, green fluorescent probe. The R-NH2 of ODIPY FL EDA free base can be coupled with aldehydes or ketones to form reversible Schiff base products. Convert to stable amine derivatives using reducing agents such as sodium borohydride or sodium cyanoborohydride. ODIPY FL EDA free base can be used to detect modified or normal deoxynucleotides and demonstrate DNA damage and genomic DNA methylation.
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Cat. No.: HY-RS04151
Research Areas:  

Others

EDA Human Pre-designed siRNA Set A contains three designed siRNAs for EDA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS23392
Research Areas:  

Others

Eda Rat Pre-designed siRNA Set A contains three designed siRNAs for Eda gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-130893A
CAS No.: 1217450-40-2
Biotin-EDA TFA is a nucleophilic biotinylation reagent used for the conjugation of various substrates and identification and quantification using biotin-conjugated fluorescent labels .
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Cat. No.: HY-RS04152
Research Areas:  

Others

EDA2R Human Pre-designed siRNA Set A contains three designed siRNAs for EDA2R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS24750
Research Areas:  

Others

Eda2r Rat Pre-designed siRNA Set A contains three designed siRNAs for Eda2r gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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