333 Results for "

FX St. Louis II

" in MedChemExpress (MCE) Product Catalog:
Products (333)

333 Results for "FX St. Louis II" in MCE Product Catalog:

75
75 Publications Verification
Art. -Nr.: HY-50937
CAS. Nr.: 894787-30-5
Target:  

MyD88

Forschungsgebiete:  

Inflammation/Immunology

ST 2825 is a specific MyD88 dimerization inhibitor. ST2825 interferes with recruitment of IRAK1 and IRAK4 by MyD88, causing inhibition of IL-1β-mediated activation of NF-κB transcriptional activity .
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14
14 Cited Publications
Art. -Nr.: HY-14808
CAS. Nr.: 496868-77-0
Reinheit:  99.18%
Synonyms: ST1926
Target:  

Apoptosis

Forschungsgebiete:  

Cancer

Adarotene is an effective apoptosis inducer, which surprisingly produces DNA damage and exhibites a potent antiproliferative activity on a large panel of human tumor cells.
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4
4 Cited Publications
Art. -Nr.: HY-101279
CAS. Nr.: 133406-29-8
Reinheit:  99.11%
Target:  

Adenylate Cyclase

Forschungsgebiete:  

Neurological Disease

ST034307 is a potent and selective adenylyl cyclase 1 (AC1) inhibitor, with IC50 of 2.3 μM.
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4
4 Cited Publications
Art. -Nr.: HY-101441
CAS. Nr.: 489416-12-8
Reinheit:  99.93%
Target:  

Arenavirus

Forschungsgebiete:  

Infection

ST-193 is a potent broad-spectrum arenavirus inhibitor; inhibits Guanarito, Junin, Lassa and Machupo virus with IC50 values of 0.44, 0.62, 1.4 and 3.1 nM, respectively.
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4
4 Cited Publications
Art. -Nr.: HY-101441A
CAS. Nr.: 2320274-72-2
Reinheit:  98.76%
Target:  

Arenavirus

Forschungsgebiete:  

Infection

ST-193 hydrochloride is a potent broad-spectrum arenavirus inhibitor; inhibits Guanarito, Junin, Lassa and Machupo virus with IC50 values of 0.44, 0.62, 1.4 and 3.1 nM, respectively.
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4
4 Cited Publications
Art. -Nr.: HY-112415
CAS. Nr.: 881179-02-8
Reinheit:  ≥98.0%
Target:  

Sialyltransferase

Forschungsgebiete:  

Metabolic Disease

Lith-O-Asp is a sialytransferase (ST) inhibitor, with IC50s of 12-37 μM.
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3
3 Cited Publications
Art. -Nr.: HY-14805
CAS. Nr.: 869572-92-9
Reinheit:  99.88%
Synonyms: ST-246
Forschungsgebiete:  

Infection

Tecovirimat (ST-246) is an orally bioavailable and selective compound against orthopoxviruses including vaccinia, monkeypox, camelpox, cowpox, ectromelia (mousepox), smallpox and variola viruses. Tecovirimat is evaluated against vaccinia, cowpox virus, ectromelia virus with EC50 values of 0.01 μM, 0.48 μM and 0.05 μM, respectively. Tecovirimat targets the orthopoxvirus protein VP37 which is necessary for membrane envelopment of intracellular mature virus particles to form enveloped virus. Tecovirimat exerts antiviral activity on the target of the cowpox virus V061 gene, which is homologous to vaccinia virus F13L, encoding a major envelope protein (p37) required for production of extracellular virus .
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3
3 Cited Publications
Art. -Nr.: HY-14805A
CAS. Nr.: 1162664-19-8
Reinheit:  99.97%
Synonyms: ST-246 monohydrate
Forschungsgebiete:  

Infection

Tecovirimat (ST-246) monohydrate is the monohydrate form of Tecovirimat (HY-14805). Tecovirimat monohydrate is an orally bioavailable and selective compound against orthopoxviruses [including vaccinia, monkeypox, camelpox, cowpox, ectromelia (mousepox), smallpox and variola viruses]. Tecovirimat monohydrate is evaluated against vaccinia, cowpox virus, ectromelia virus with EC50 values of 0.01 μM, 0.48 μM and 0.05 μM, respectively. Tecovirimat monohydrate targets the orthopoxvirus protein VP37 which is necessary for membrane envelopment of intracellular mature virus particles to form enveloped virus. Tecovirimat monohydrate exerts antiviral activity on the target of the cowpox virus V061 gene, which is homologous to vaccinia virus F13L, encoding a major envelope protein (p37) required for production of extracellular virus. Tecovirimat monohydrate could be used in the study for orthopoxvirus-induced diseases .
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3
3 Cited Publications
Art. -Nr.: HY-P99444
CAS. Nr.: 2173054-79-8
Synonyms: MSTT 1041A; RG 6149
Astegolimab (MSTT 1041A; RG 6149) is a human IgG2 monoclonal antibody. Astegolimab blocks IL-33 signaling by targeting the IL-33 receptor ST2. Astegolimab reduces p53 expression, mitigates IL33-upregulated SASP factors such as IL1α, IL6 and MCP1. Astegolimab mitigates IL33-increased p-p65/p65 ratio. Astegolimab blocks CM-induced neutrophil extracellular trap (NET) formation. Astegolimab is used in chronic obstructive pulmonary disease (COPD) and myocardial research .
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2
2 Cited Publications
Art. -Nr.: HY-P77003
Reinheit:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL24; IL-4-Induced Secreted Protein; Prev. ST16; Mob-5; Interleukin-24; MDA7; IL10B; Melanoma Differentiation Association Protein 7; IL-24; Suppression Of Tumorigenicity 16 Protein; C49A; Melanocyte-Associated Mda-7; FISP; MDA-7; Suppression Of Tumorigeni
Species:  
Human
Source:  
HEK293
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2
2 Cited Publications
Art. -Nr.: HY-P7260
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL20; Chemokine (C-C Motif) Ligand 20; Prev. SCYA20; C-C Motif Chemokine 20; LARC; CC Chemokine LARC; MIP-3a; MIP-3-Alpha; ST38; Exodus-1; CKb4; MIP3A; Small Inducible Cytokine Subfamily A (Cys-Cys), Member 20; Beta Chemokine Exodus-1; Liver And Activati
Species:  
Human
Source:  
CHO
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2
2 Cited Publications
Art. -Nr.: HY-P7263
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL20; Chemokine (C-C Motif) Ligand 20; Prev. SCYA20; C-C Motif Chemokine 20; LARC; CC Chemokine LARC; MIP-3a; MIP-3-Alpha; ST38; Exodus-1; CKb4; MIP3A; Small Inducible Cytokine Subfamily A (Cys-Cys), Member 20; Beta Chemokine Exodus-1; Liver And Activati
Species:  
Mouse
Source:  
E. coli
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1
1 Cited Publications
Art. -Nr.: HY-13071
CAS. Nr.: 7759-35-5
Reinheit:  99.83%
Synonyms: ST-1435; Elcometrine
Target:  

Progesterone Receptor

Forschungsgebiete:  

Endocrinology

Nestoron (ST-1435) is a 19-norprogesterone derivative with high affinity and selectivity for progesterone receptors. Nestoron is a highly selective and potent progestogen that can be used as a hormonal contraceptive .
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1
1 Cited Publications
Art. -Nr.: HY-103110
CAS. Nr.: 1210-81-7
Reinheit:  99.70%
Forschungsgebiete:  

Neurological Disease

ST1936 is a selective, nanomolar affinity 5-HT6 receptor agonist with Ki values of 13 nM, 168 nM and 245 nM for human 5-HT6, 5-HT7 and 5-HT2B receptors, respectively. ST1936 also shows moderate affinity (Ki of 300 nM) for human and rat α2 adrenergic receptor .
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1
1 Cited Publications
Art. -Nr.: HY-E70057
CAS. Nr.: 67339-00-8
Synonyms: ST8Sia VI; GD3 synthase
Target:  

Endogenous Metabolite

Forschungsgebiete:  

Metabolic Disease

alpha-2,8-Sialyltransferase (CstII) (ST8Sia VI) is a member of alpha2,8-sialyltransferase (ST8Sia) family, is often used in biochemical studies. alpha-2,8-Sialyltransferase (CstII) catalyzes elongation of the α2,8-linked oligo/polysialic acid chain on the Sia residue transferred .
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1
1 Cited Publications
Art. -Nr.: HY-P76370
Reinheit:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL6ST; Interleukin Receptor Beta Chain; Interleukin 6 Cytokine Family Signal Transducer; Membrane Glycoprotein Gp130; Interleukin-6 Receptor Subunit Beta; IL6ST Nirs Variant 5; Membrane Glycoprotein 130; IL6ST Nirs Variant 2; IL-6RB; IL6ST Nirs Variant 3
Species:  
Mouse
Source:  
HEK293
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1
1 Cited Publications
Art. -Nr.: HY-P76094
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ST6GAL1; ST6GalI; Prev. SIAT1; Sialyltransferase 1 (Beta-Galactoside Alpha-2,6-Sialyltransferase); Beta-Galactoside Alpha-2,6-Sialyltransferase 1; Sialyltransferase 1 (Beta-Galactoside Alpha-2,6-Sialytransferase); CDw75; Beta-Galactoside Alpha-(2,6)-Sialy
Species:  
Mouse
Source:  
HEK293
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1
1 Cited Publications
Art. -Nr.: HY-P70615
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1RL1; ST2V; Interleukin 1 Receptor Like 1; Homolog Of Mouse Growth Stimulation-Expressed; DER4; Suppressor Of Tumorigenicity 2; ST2; Interleukin 1 Receptor-Like 1 Isoform 2; T1; Interleukin 1 Receptor-Like 1 Isoform 1; Interleukin-1 Receptor-Like 1; Int
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Art. -Nr.: HY-P74876
Reinheit:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HTRA2; Serine Protease 25; Prev. PRSS25; Protease, Serine, 25; OMI; Epididymis Secretory Sperm Binding Protein; High Temperature Requirement Protein A2; Mitochondrial Serine Protease; Serine Protease HTRA2, Mitochondrial; HtrA-Like Serine Protease; Omi St
Species:  
Human
Source:  
E. coli
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1
1 Cited Publications
Art. -Nr.: HY-P700200AF
Reinheit:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL24; IL-4-Induced Secreted Protein; Prev. ST16; Mob-5; Interleukin-24; MDA7; IL10B; Melanoma Differentiation Association Protein 7; IL-24; Suppression Of Tumorigenicity 16 Protein; C49A; Melanocyte-Associated Mda-7; FISP; MDA-7; Suppression Of Tumorigeni
Species:  
Mouse
Source:  
E. coli
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