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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
FdUMP
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "FdUMP" in MCE Product Catalog:
2
Target:
Research Areas:
Fosifloxuridine nafalbenamide (NUC-3373), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor. Fosifloxuridine nafalbenamide has anticancer activity. Fosifloxuridine nafalbenamide has the potential to evoke a host immune response and enhance immunoresearch .
Synonyms: 2’-Deoxy-5-Fluorouridine 5’-phosphate triethylammonium
Research Areas:
FdUMP triethylammonium is the intracellular active form of 5-fluorouracil (5-FU). 5-FU is converted to FdUMP after being transported into the cell by various enzymes. FdUMP forms a ternary complex with thymidylate synthase and its cofactor 5,10-methylene tetrahydrofolate, inhibiting the activity of thymidylate synthase, which in turn leads to the suppression of DNA synthesis.
Cat. No.: HY-107084
CAS No.: 86976-77-4
Target:
Research Areas:
TT-62 is an orally active derivative of FdUMP, which is the active metabolite of 5-Fluorouracil (HY-90006). TT-62 can be used for the research of cancer .
Cat. No.: HY-109115R
CAS No.: 1332837-31-6
Synonyms: NUC-3373 (Standard)
Research Areas:
Fosifloxuridine nafalbenamide (Standard) is the analytical standard of Fosifloxuridine nafalbenamide (HY-109115). This product is intended for research and analytical applications. Fosifloxuridine nafalbenamide (NUC-3373), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor. Fosifloxuridine nafalbenamide has anticancer activity. Fosifloxuridine nafalbenamide has the potential to evoke a host immune response and enhance immunoresearch .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
