85 Results for "

G-{d-Arg}-GDSP

" in MedChemExpress (MCE) Product Catalog:
Products (85)

85 Results for "G-{d-Arg}-GDSP" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P7061A
Research Areas:  

Infection Endocrinology

ALX 40-4C Trifluoroacetate is a small peptide inhibitor of the chemokine receptor CXCR4, inhibits SDF-1 from binding CXCR4 with a Ki of 1 μM, and suppresses the replication of X4 strains of HIV-1; ALX 40-4C Trifluoroacetate also acts as an antagonist of the APJ receptor, with an IC50 of 2.9 μM.
loading...
    loading...
Cat. No.: HY-P3582
CAS No.: 96497-82-4
Target:  

GnRH Receptor

Research Areas:  

Endocrinology

sGnRH-A is a salmon gonadotropin-releasing hormone (GnRH) analogue. sGnRH-A stimulates growth hormone secretion. sGnRH-A also can be used as an inducer of ovulation by artificial insemination .
loading...
    loading...
Cat. No.: HY-P10861A
Target:  

Tau Protein

Research Areas:  

Neurological Disease

RI-AG03 acetate is a proteolytically stable tau aggregation inhibitor that crosses the blood-brain barrier and exhibits oral efficacy. RI-AG03 acetate inhibits tau aggregation and promotes the formation of alternative amorphous aggregates that are non-amyloidogenic. RI-AG03 acetate mediates cellular uptake through direct membrane penetration and macropinocytosis, and its conjugation with cell-penetrating peptide sequences (CPPs) enhances the binding of cells to liposomes. RI-AG03 acetate suppresses aggregation-dependent neurodegenerative and behavioral phenotypes, and extends the lifespan of Drosophila models of tauopathy. RI-AG03 acetate can be used for research on tau-related diseases such as Alzheimer's disease .
loading...
    loading...
Cat. No.: HY-P4474
CAS No.: 17011-78-8
Target:  

Peptides

Research Areas:  

Others

Pz-Pro-Leu-Gly-Pro-d-Arg is a synthetic polypeptide substrate. Pz-Pro-Leu-Gly-Pro-d-Arg can be used to detect the collagenase-like activity of enzymes from various sources, such as Bacillus sp. AH-101 .
loading...
    loading...
Cat. No.: HY-P5506
CAS No.: 144555-23-7
Target:  

Complement System

Research Areas:  

Others

C5a Receptor agonist, W5Cha (Peptide 1) is a selective complement C5a receptor (C5aR) agonist (EC50=0.2 μM), a hexapeptide derived from the C-terminus of C5a with specific amino acid modifications. C5a Receptor agonist, W5Cha is able to interact with the Arg-206 site of the C5a receptor through its C-terminal arginine, thereby activating the receptor .
loading...
    loading...
Cat. No.: HY-P3530
CAS No.: 111844-21-4
Target:  

Integrin

Research Areas:  

Others

G-{d-Arg}-GDSP is an RGD peptide analogue that binds to the adhesion receptor of integrins and inhibits cellular fibronectin attachment as well as osteoclast resorption .
loading...
    loading...
Cat. No.: HY-P10644A
Target:  

Peptides

Research Areas:  

Cancer

CPP9 TFA is a small, amphipathic, cyclic cell penetrating peptide (CPP). CPPs bind directly to the plasma membrane phospholipids and enter mammalian cells via endocytosis, followed by efficient release from the endosome. CPP9 TFA can be used for intracellular delivery of therapeutic agents and chemical probes .
loading...
    loading...
Cat. No.: HY-P1194
CAS No.: 91224-37-2
Target:  

Neurokinin Receptor

Research Areas:  

Inflammation/Immunology

Spantide I, a substance P analog, is a selective NK1 receptor antagonist, with Ki values of 230 nM and 8150 nM for NK1 and NK2 receptor, respectively. Spantide I provides an approach to reduce type 1 and enhance the type 2 cytokine IL-10 in the infected cornea, leading to a significant reduction in corneal perforation .
loading...
    loading...
Cat. No.: HY-P10861
Target:  

Tau Protein

Research Areas:  

Neurological Disease

RI-AG03 is a proteolytically stable tau aggregation inhibitor that crosses the blood-brain barrier and exhibits oral efficacy. RI-AG03 inhibits tau aggregation and promotes the formation of alternative amorphous aggregates that are non-amyloidogenic. RI-AG03 mediates cellular uptake through direct membrane penetration and macropinocytosis, and its conjugation with cell-penetrating peptide sequences (CPPs) enhances the binding of cells to liposomes. RI-AG03 suppresses aggregation-dependent neurodegenerative and behavioral phenotypes, and extends the lifespan of Drosophila models of tauopathy. RI-AG03 can be used for research on tau-related diseases such as Alzheimer's disease .
loading...
    loading...
Cat. No.: HY-P10649
CAS No.: 1831064-62-0
Target:  

Peptides

Research Areas:  

Cancer

CPP12 is a small, amphipathic, cyclic cell-penetrating peptide (CPP). CPP12 binds directly to plasma membrane phospholipids, enters mammalian cells via endocytosis, and then efficiently escapes from endosomes. CPP12 can be used for the intracellular delivery of drugs and chemical probes .
loading...
    loading...
Cat. No.: HY-P10649A
Target:  

Peptides

Research Areas:  

Cancer

CPP12 TFA is a small, amphipathic, cyclic cell-penetrating peptide (CPP). CPP12 TFA binds directly to plasma membrane phospholipids, enters mammalian cells via endocytosis, and then efficiently escapes from endosomes. CPP12 TFA can be used for the intracellular delivery of drugs and chemical probes .
loading...
    loading...
Cat. No.: HY-P4548
CAS No.: 136132-77-9
Synonyms: Boc-RVRR-AMC
Target:  

Furin

Research Areas:  

Others

Boc-Arg-Val-Arg-Arg-AMC hydrochloride (Boc-RVRR-AMC) is a synthetic fluorogenic substrate that is efficiently cleaved by furin .
loading...
    loading...
Cat. No.: HY-P3870
CAS No.: 118476-85-0
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

DALDA is a potent and highly selective μ-opioid receptor agonist with a Ki of 1.69 nM. DALDA shows antinociceptive and respiratory effects .
loading...
    loading...
Cat. No.: HY-P2498A
Target:  

Cathepsin

Research Areas:  

Cancer

Cathepsin D and E FRET Substrate acetate is a fluorogenic substrate for cathepsins D and E and not for B, H or L. The cleavage occurs at the Phe-Phe amide bond resul. Cathepsin D and E FRET Substrate is a valuable tool for routine assays and for mechanistic studies on cathepsins E and D .
loading...
    loading...
Cat. No.: HY-P3397A
Target:  

GHR

Research Areas:  

Cancer

JV-1-36 acetate is a growth hormone-releasing hormone (GHRH) antagonist. JV-1-36 acetate inhibits the production of reactive oxygen species in A549 lung cancer cells. JV-1-36 can be used to study the effect of GHRH antagonists in vitro .
loading...
    loading...
Cat. No.: HY-P4764
CAS No.: 819048-44-7
Target:  

Melanocortin Receptor

Research Areas:  

Cardiovascular Disease

Ac-DArg-c[Cys-Glu-His-DPhe-Arg-Trp-Cys]-NH 2 is a cyclic octapeptide with MC4R agonism. Ac-DArg-c[Cys-Glu-His-DPhe-Arg-Trp-Cys]-NH 2 significantly increases heart rate and blood pressure .
loading...
    loading...
Cat. No.: HY-103544
CAS No.: 96736-12-8
Purity:  98.48%
[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P, a Substance P derivative, is a biased agonist toward neuropeptide and chemokine receptors. [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P activates G12. [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P binds to IL-8 and GRP receptors. [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P inhibits ERK-2 activation, activates JNK activity. [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P stimulates an increase in neutrophil migration and Ca 2+ mobilization. [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P is also a bombesin antagonist, and inhibits the growth of small cell lung cancer
loading...
    loading...
Cat. No.: HY-P3870A
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

DALDA acetate is a potent and highly selective μ-opioid receptor agonist with a Ki of 1.69 nM. DALDA acetate shows antinociceptive and respiratory effects .
loading...
    loading...
Cat. No.: HY-P3869
CAS No.: 100304-60-7
Synonyms: [D-Arg2]Dermorphin-(1-4) amide
Target:  

Peptides

Research Areas:  

Neurological Disease

Lumekefamide ([D-Arg2]Dermorphin-(1-4) amide) is a N-terminal shorter peptide amide of [D-Arg2]dermorphin with the hypothermic effect. Lumekefamide shows analgesic activity and degradation in soluble mouse liver and brain extracts .
loading...
    loading...
Cat. No.: HY-P5753
CAS No.: 1873323-60-4
Target:  

Bacterial

Research Areas:  

Infection

JB-95, a β-hairpin macrocyclic peptide, exhibits potent antimicrobial activity against Escherichia coli. JB-95 can selectively disrupt the outer membrane but not the inner membrane of E. coli .
loading...
    loading...