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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
GDI2
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "GDI2" in MCE Product Catalog:
Cat. No.: HY-156244
Target:
Research Areas:
PROTAC GDI2 Degrader-1 is a GDI2 PROTAC degrader with a DC50 value of 1.48 μM and a Kd value of 23.9 μM. PROTAC GDI2 Degrader-1 triggers paraptosis in tumor cells via endoplasmic reticulum expansion and fusion, endoplasmic reticulum stress, unfolded protein response, and cytoplasmic vacuolization. PROTAC GDI2 Degrader-1 exhibits significant in vivo anti-tumor activity in pancreatic cancer xenograft models. PROTAC GDI2 Degrader-1 can be used for research related to pancreatic cancer .
Cat. No.: HY-RS05360
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Research Areas:
GDI2 Human Pre-designed siRNA Set A contains three designed siRNAs for GDI2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS20740
Target:
Research Areas:
Gdi2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gdi2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-156242
CAS No.: 1906915-49-8
Target:
Research Areas:
BQZ-485 is a a potent GDI2 inhibitor through the interaction with Tyr245. BQZ-485 disrupts the intrinsic GDI2-Rab1A interaction, thereby abolishing vesicular transport from the endoplasmic reticulum (ER) to the Golgi apparatus and initiating subsequent paraptosis events .
Cat. No.: HY-RS27252
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Research Areas:
Gdi2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Gdi2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P71737
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GDI-2; GDP dissociation inhibitor 2; Guanosine diphosphate dissociation inhibitor 2; Rab GDI beta; RABGDIB
Species:
Source:
Cat. No.: HY-175690
CAS No.: 61046-20-6
Target:
Research Areas:
CIA P1 ligand 6 is a CIAP1 ligand and can be used for the synthesis of PROTACs, such as PROTAC GDI2 Degrader-1 (HY-156244) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
