28 Results for "

GLP-2

" in MedChemExpress (MCE) Product Catalog:
Products (28)

28 Results for "GLP-2" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P2625
CAS No.: 275801-62-2
Target:  

GCGR

Research Areas:  

Metabolic Disease

GLP-2(3-33), generated naturally by dipeptidylpeptidase IV (DPPIV), acts as a partial agonist on GLP-2 receptor (EC50=5.8 nM) [2].
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2
2 Cited Publications
Cat. No.: HY-P1624
CAS No.: 197922-42-2
Synonyms: ALX-0600
Teduglutide (ALX-0600) is an analog of human glucagon like peptide-2 (GLP-2). Teduglutide can activate the expression of nuclear receptor subfamily 4 group a member 1 (NR4a1)/nur77 and intestinal FXR signaling in human hepatic stellate cells, thereby improving liver inflammation and fibrosis in mice with sclerosing cholangitis. Teduglutide can alleviate intestinal dysfunction in mice, improve lung injury, alleviate obesity related neuroinflammation and cell apoptosis [2] .
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2
2 Cited Publications
Cat. No.: HY-P70239
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuPro-glucagon/GCG, His ; Glucagon; Glicentin; Glicentin-Related Polypeptide; GRPP; Oxyntomodulin; OXM; OXY; Glucagon; Glucagon-Like Peptide 1; GLP-1; Incretin Hormone; Glucagon-like Peptide 1; GLP-1; Glucagon-Like Peptide 2; GLP-2; GCG
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P2221
CAS No.: 914009-86-2
Synonyms: ZP1848
Target:  

GCGR

Research Areas:  

Inflammation/Immunology

Glepaglutide (ZP1848), a long-acting GLP-2 analogue, is a potent GLP-2R agonist. Glepaglutide reduces faecal output and increases intestinal absorption. Glepaglutide alleviates small intestinal inflammation. Glepaglutide can be used in the research of inflammatory bowel disease (IBD) and Crohn’s disease [2] .
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1
1 Cited Publications
Cat. No.: HY-P2221B
Synonyms: ZP1848 acetate
Target:  

GCGR

Research Areas:  

Inflammation/Immunology

Glepaglutide (ZP1848) acetate, a long-acting GLP-2 analogue, is a potent GLP-2R agonist. Glepaglutide acetate reduces faecal output and increases intestinal absorption. Glepaglutide acetate alleviates small intestinal inflammation. Glepaglutide acetate can be used in the research of inflammatory bowel disease (IBD) and Crohn’s disease [2] .
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1
1 Cited Publications
Cat. No.: HY-P3291
CAS No.: 2296814-85-0
Synonyms: ZP7570
Target:  

GCGR

Research Areas:  

Metabolic Disease

Dapiglutide (ZP7570) is a long-acting glucagon-like peptide-1 receptor 1R (GLP-1R)/Glucagon-like peptide-2 receptor (GLP-2R) dual agonist. Dapiglutide alleviates intestinal dysfunction in a mouse short bowel model and has anti-obesity effects [2] .
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Cat. No.: HY-P1024
CAS No.: 223460-79-5
Synonyms: GLP-2 (human); Glucagon-like peptide 2 (human)
Target:  

GCGR

Research Areas:  

Metabolic Disease

GLP-2(1-33) (human) is an enteroendocrine hormone which can bind to the GLP-2 receptor and stimulate the growth of intestinal epithelium.
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Cat. No.: HY-P1714
CAS No.: 1295353-98-8
Synonyms: FE 203799
Target:  

GLP Receptor

Research Areas:  

Metabolic Disease

Apraglutide (FE 203799), a synthetic 33-amino-acid peptide and a long-acting GLP-2 analogue, enhances adaptation and linear intestinal growth in a neonatal piglet model of short bowel syndrome with total resection of the ileum .
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Cat. No.: HY-P3498
CAS No.: 914009-84-0
Synonyms: ZP1846
Target:  

GCGR

Research Areas:  

Others

Elsiglutide (ZP1846) is a GLP-2 analogue, an orally active and selective GLP-2 receptor agonist, increases cell proliferation and reduces apoptosis in the intestine. Elsiglutide improves Lapatinib (HY-50898)-induced diarrhoea in rat model [2].
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Cat. No.: HY-P4839
CAS No.: 99120-49-7
Target:  

Peptides

Research Areas:  

Metabolic Disease

GLP-2 (1-34) (human) is a polypeptide released from the intestine within minutes after food intake. GLP-2 (1-34) (human) can be used for the research of bone remodeling processes .
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Cat. No.: HY-P1714A
Synonyms: FE 203799 TFA
Target:  

GLP Receptor

Research Areas:  

Metabolic Disease

Apraglutide TFA (FE 203799 TFA), a synthetic 33-amino-acid peptide and a long-acting GLP-2 analogue, enhances adaptation and linear intestinal growth in a neonatal piglet model of short bowel syndrome with total resection of the ileum .
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Cat. No.: HY-P1624S1
Synonyms: ALX-0600-Leu(13C6,15N) sodium
Teduglutide-Leu( 13C6, 15N) (ALX-0600-Leu( 13C6, 15N)) sodium is the 13C- and 15N-labeled Teduglutide (HY-P1624). Teduglutide (ALX-0600) is an analog of human glucagon like peptide-2 (GLP-2). Teduglutide can activate the expression of nuclear receptor subfamily 4 group a member 1 (NR4a1)/nur77 and intestinal FXR signaling in human hepatic stellate cells, thereby improving liver inflammation and fibrosis in mice with sclerosing cholangitis. Teduglutide can alleviate intestinal dysfunction in mice, improve lung injury, alleviate obesity related neuroinflammation and cell apoptosis [2] .
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Cat. No.: HY-P1624A
Synonyms: ALX-0600 TFA
Teduglutide TFA is a dipeptidyl peptidase IV resistant glucagon-like peptide 2 (GLP-2) analogue. Teduglutide TFA can activate the expression of nuclear receptor subfamily 4 group a member 1 (NR4a1)/nur77 and intestinal FXR signaling in human hepatic stellate cells, thereby improving liver inflammation and fibrosis in mice with sclerosing cholangitis. Teduglutide TFA can alleviate intestinal dysfunction in mice, improve lung injury, alleviate obesity related neuroinflammation and cell apoptosis [2] .
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Cat. No.: HY-P2625S
Research Areas:  

Metabolic Disease

GLP-2(3-33) (Leu- 13C6, 15N) is 13C and 15N labeled GLP-2(3-33) (HY-P2625). GLP-2(3-33), generated naturally by dipeptidylpeptidase IV (DPPIV), acts as a partial agonist on GLP-2 receptor (EC50=5.8 nM).
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Cat. No.: HY-P2625S1
Research Areas:  

Metabolic Disease

GLP-2(3-33) (Leu- 13C6, 15N) TFA is 13C and 15N labeled GLP-2(3-33) (HY-P2625). GLP-2(3-33), generated naturally by dipeptidylpeptidase IV (DPPIV), acts as a partial agonist on GLP-2 receptor (EC50=5.8 nM).
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Cat. No.: HY-173479
CAS No.: 3108380-54-4
Target:  

GLP Receptor

GLP-1R agonist 30 is a selective and orally active GLP-1R agonist with an EC50 of 0.048 nM. GLP-1R has excellent selectivity, with EC50 greater than 20 μM for GLP-2R, GIPR, and GCPR. GLP-1R agonist significantly increases cAMP-stimulating activity while markedly reducing hERG inhibitory activities. GLP-1R agonist has preferable absorption and excellent β-arrestin pathway selectivity. GLP-1R agonist effectively improves glucose tolerance and promoted insulin secretion in B-hGLP1R knock-in mice .
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Cat. No.: HY-P1142
CAS No.: 195262-56-7
Target:  

Apoptosis

Research Areas:  

Others

GLP-2(rat) is an intestinal growth factor. GLP-2(rat) stimulates cell proliferation and inhibits apoptosis. GLP-2(rat) enhances mucosal mass and function in residual small intestine after massive small bowel resection (MSBR) [2].
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Cat. No.: HY-116453
CAS No.: 1354812-99-9
RO5527239 is an orally active TGR5 agonist, that induces a stimulatory response from intestinal L cells and specificially secrets the endogenous hormone GLP-2 .
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Cat. No.: HY-P1142A
Target:  

Apoptosis

Research Areas:  

Others

GLP-2(rat) TFA is an intestinal growth factor. GLP-2(rat) TFA stimulates cell proliferation and inhibits apoptosis. GLP-2(rat) TFA enhances mucosal mass and function in residual small intestine after massive small bowel resection (MSBR) [2].
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Cat. No.: HY-P10842
Target:  

GLP Receptor Akt

d-GLP-2 E33A is an agonist for the glucagon-like peptide 2 receptor (GLP-2R) with an EC50 of 414 nM. d-GLP-2 E33A can activate GLP-2R and increase the phosphorylation of AKT, but has no stimulative effect on GLP-1R. d-GLP-2 E33A can be used in the study of diseases such as intestinal malabsorption and inflammatory bowel diseases .
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