41 Results for "

GP1

" in MedChemExpress (MCE) Product Catalog:
Products (41)

41 Results for "GP1" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P0323A
Synonyms: LCMV GP(33-41) C-peptide TFA
Target:  

Arenavirus

Research Areas:  

Infection

GP(33-41) TFA, a 9-aa-long peptide, is the optimal sequence of the GP1 epitope of lymphocytic choriomeningitis virus. GP(33-41) TFA can upregulate H-2D b molecules at the RMA-S (Db Kb) cell surface with a SC50 of 344 nM [1].
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P99832
CAS No.: 1792982-57-0
Synonyms: c13C6-FR1

Target:  

Filovirus

Research Areas:  

Infection

Cosfroviximab (c13C6-FR1) is a mouse/human chimeric monoclonal antibody against Ebola virus glycoprotein (EBOV-GP) .
loading...
    loading...
Cat. No.: HY-W009141
CAS No.: 542-44-9
Synonyms: Glyceryl palmitate
Category:  

Plants

1-Monopalmitin (Glyceryl palmitate) is an activator of the PI3K/Akt pathway and an inhibitor of P-glycoprotein (P-gp). 1-Monopalmitin can induce G2/M arrest and caspase-dependent apoptosis in cancer cells, while inhibiting IAPs protein expression. 1-Monopalmitin can increase drug accumulation by inhibiting P-gp activity in intestinal Caco-2 cells. 1-Monopalmitin has the ability to induce protective autophagy and apoptosis of lung cancer cells (IC50=50-58 μg/mL), with low toxicity to normal cells [1] .
loading...
    loading...
Cat. No.: HY-110050
CAS No.: 511532-96-0
Purity:  99.66%
GP1a is a potent agonist of cannabinoid receptor 2 (CB2). Gp1a is beneficial to skin wound healing. GP1a inhibits inflammation and fibrogenesis while promoting re-epithelialization [1].
loading...
    loading...
Cat. No.: HY-W035709
CAS No.: 485-65-4
Synonyms: Dihydrocinchonine
Hydrocinchonine (Dihydrocinchonine) is a multidrug resistance (MDR)-reversal agent. Hydrocinchonine directly inhibits the function and expression of P-gp, which is the mechanism by which it reverses MDR. Hydrocinchonine exerts synergistic apoptotic effect with Paclitaxel (HY-B0015) in MES-SA/DX5 cells. Hydrocinchonine can be used for the study of gynecological malignant tumors (such as uterine sarcoma) with drug resistance caused by excessive expression of P-gp .
loading...
    loading...
Cat. No.: HY-177580
CAS No.: 1423134-36-4
Target:  

Integrin

Research Areas:  

Cardiovascular Disease

GP1 precursor has high affinity to GPIIb/IIIa receptors of activated platelets. GP1 precursor can be radiolabeled with [ 18F] and used as a PET Tracer for visualizing active platelet aggregation at the molecular level. GP1 precursor can be used for the detection of Thrombi [1].
loading...
    loading...
Cat. No.: HY-P0323
CAS No.: 161928-86-5
Synonyms: LCMV GP(33-41) C-peptide
Target:  

Arenavirus

Research Areas:  

Infection

GP(33-41), a 9-aa-long peptide, is the optimal sequence of the GP1 epitope of lymphocytic choriomeningitis virus, and can upregulate H-2D b molecules at the RMA-S (Db Kb) cell surface with a SC50 of 344 nM [1].
loading...
    loading...
Cat. No.: HY-RS05607
Research Areas:  

Others

GP1BA Human Pre-designed siRNA Set A contains three designed siRNAs for GP1BA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-149277
CAS No.: 1807320-40-6
Target:  

P-glycoprotein

Research Areas:  

Cancer

FM04 is a potent P-glycoprotein (P-gp) inhibitor (EC50=83 nM). FM04 inhibits P-gp in 2 mechanism: (1)FM04 binds to Q1193, followed by interacting with the functionally critical residues H1195 and T1226; or (2)FM04 binds to I1115 (a functionally critical residue itself), disrupting the R262-Q1081-Q1118 interaction pocket and uncoupling ICL2-NBD2 interaction and thereby inhibiting P-gp .
loading...
    loading...
Cat. No.: HY-W035709R
CAS No.: 485-65-4
Synonyms: Dihydrocinchonine (Standard)
Hydrocinchonine (Dihydrocinchonine) (Standard) is the analytical standard of Hydrocinchonine (HY-W035709). This product is used for research and analytical purposes.Hydrocinchonine is a multidrug resistance (MDR)-reversal agent. Hydrocinchonine directly inhibits the function and expression of P-gp, which is the mechanism by which it reverses MDR. Hydrocinchonine exerts synergistic apoptotic effect with Paclitaxel (HY-B0015) in MES-SA/DX5 cells. Hydrocinchonine can be used for the study of gynecological malignant tumors (such as uterine sarcoma) with drug resistance caused by excessive expression of P-gp .
loading...
    loading...
Cat. No.: HY-Z15823
CAS No.: 38321-02-7
Synonyms: Dexverapamil
(R)-Verapamil (Dexverapamil) is an optically enantiomer of the oral-active Verapamil (HY-14275). (R)-Verapamil has a relatively low affinity for L-type calcium channels (Cav1.2) (IC50 > 300 μM), and its IC50 for sodium channels (sodium channel) is 3.19 μM. (R)-Verapamil exhibits SSTR2 agonistic activity, with an EC50 of 1.3 μM. (R)-Verapamil significantly downregulates the expression of TXNIP protein in diabetic mouse models and significantly inhibits β-cell apoptosis (apoptosis), effectively controlling blood sugar. (R)-Verapamil can be used as a PET tracer for the function of P-glycoprotein (P-gp) .
loading...
    loading...
Cat. No.: HY-RS05608
Research Areas:  

Others

GP1BB Human Pre-designed siRNA Set A contains three designed siRNAs for GP1BB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-RS20029
Research Areas:  

Others

Gp1ba Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gp1ba gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-RS05908
Research Areas:  

Others

GTPBP1 Human Pre-designed siRNA Set A contains three designed siRNAs for GTPBP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-P75715
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) GP1 / Glycoprotein Protein (His)
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-150756
CAS No.: 3032283-85-2
Target:  

Filovirus

Research Areas:  

Infection

EBOV-GP-IN-1 (Compound 28) is a potent Ebola entry inhibitor with an IC50 of 0.05 μM against Ebola virus envelope glycoprotein (EBOV-GP) .
loading...
    loading...
Cat. No.: HY-P75717
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Ebola virus EBOV (subtype Sudan, strain Gulu) GP1 / Glycoprotein Protein (His)
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P75718
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Ebola virus EBOV (subtype Sudan, strain Gulu) GP1 / Glycoprotein Protein (His)
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P75721
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) GP1 / Glycoprotein Protein (His)
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P76884
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Ebola virus EBOV (Subtype Sudan, strain Gulu) Glycoprotein / GP1 (mucin domain deleted) Protein (His)
Species:  
Source:  
loading...
    loading...