10 Results for "

GPR3

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "GPR3" in MCE Product Catalog:

21
21 Cited Publications
Cat. No.: HY-108496
CAS No.: 26993-30-6
Purity:  ≥99.0%
Synonyms: S1P
Sphingosine-1-phosphate (S1P) is an agonist of S1P1-5 receptors and a ligand of GPR3, GPR6 and GPR12. Sphingosine-1-phosphate is an intracellular second messenger and mobilizes Ca 2+ as an extracellular ligand for G protein-coupled receptors . Sphingosine-1-phosphate is an important lipid mediator generated from Sphingomyelin (HY-113498) or other membrane phospholipids . Sphingosine-1-phosphate stimulates the DNA synthesis, cell proliferation and migration .
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1
1 Cited Publications
Cat. No.: HY-12664
CAS No.: 1637300-25-4
Purity:  98.01%
Target:  

Orphan GPCR

Research Areas:  

Others

AF64394 is a GPR3 inverse agonist, with a pIC50 of 7.3.
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Cat. No.: HY-155318A
CAS No.: 1983120-51-9
Purity:  99.90%
Target:  

Orphan GPCR

Research Areas:  

Endocrinology

GPR3 agonist-2(compound 32) is a potent full agonist of G protein-coupled receptor 3, with the IC50of 260 nM .
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Cat. No.: HY-108496S
CAS No.: 2260670-15-1
Purity:  99.00%
Synonyms: S1P-d7
Sphingosine-1-phosphate-d7 is the deuterium labeled Sphingosine-1-phosphate. Sphingosine-1-phosphate (S1P) is an agonist of S1P1-5 receptors and a ligand of GPR3, GPR6 and GPR12.?Sphingosine-1-phosphate is an intracellular second messenger and mobilizes Ca2+ as an extracellular ligand for G protein-coupled receptors . Sphingosine-1-phosphate is an important lipid mediator generated from Sphingomyelin (HY-113498) or other membrane phospholipids .
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Cat. No.: HY-RS05700
Research Areas:  

Others

GPR3 Human Pre-designed siRNA Set A contains three designed siRNAs for GPR3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS17955
Research Areas:  

Others

Gpr3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Gpr3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS24426
Research Areas:  

Others

Gpr3 Rat Pre-designed siRNA Set A contains three designed siRNAs for Gpr3 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-183657A
Research Areas:  

Neurological Disease

GPR3 inverse agonist-1 TFA is a selective and competitive GPR3 inverse agonist with an EC50 of 5 μM. GPR3 inverse agonist-1 TFA inhibits GPR3-dependent Gs activity, stabilizes a specific receptor conformation, and reduces cAMP levels. GPR3 inverse agonist-1 TFA can be used for the research of Alzheimer's disease .
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Cat. No.: HY-157013
UR-MB-355, a GPR3 ligand, binds to GPR3 and closely related receptors, GPR6 and GPR12, with similar submicromolar affinities .
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Cat. No.: HY-182011
CAS No.: 3029155-57-2
Target:  

GPR6

Research Areas:  

Neurological Disease

GPR6 inverse agonist 2 (Compound 575) is a selective GPR6 inverse agonist, with IC50 values of < 0.1 μM and 1~30 μM against GPR6 and GPR3, respectively. GPR6 inverse agonist 2 exhibits preliminary cardiac safety, with an IC50 of 21.71 μM for hERG. GPR6 inverse agonist 2 can be used in the research of movement disorders such as Parkinson's disease .
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