59 Results for "

IGF-I

" in MedChemExpress (MCE) Product Catalog:
Products (59)

59 Results for "IGF-I" in MCE Product Catalog:

27
27 Publications Verification
Cat. No.: HY-P7018
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuIGF-1; IGF-IA; Somatamedin C; MGF; IGF-I
Species:  
Source:  
loading...
    loading...
12
12 Cited Publications
Cat. No.: HY-P7070
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rMuIGF-1; IGF-IA; Somatamedin C; MGF; IGF-I
Species:  
Source:  
loading...
    loading...
6
6 Cited Publications
Cat. No.: HY-16381
CAS No.: 396091-73-9
Synonyms: SOM230
Target:  

Somatostatin Receptor

Research Areas:  

Endocrinology Cancer

Pasireotide (SOM230), a long-acting cyclohexapeptide somatostatin analogue, can improve agonist activity at somatostatin receptors (subtypes sst1/2/3/4/5, pKi=8.2/9.0/9.1/<7.0/9.9, respectively). Pasireotide can suppress GH, IGF-I and ACTH secretion, indicating potential efficacy in acromegaly and Cushing's disease. Pasireotide also exhibits antisecretory, antiproliferative, and proapoptotic activity .
loading...
    loading...
6
6 Cited Publications
Cat. No.: HY-P70788
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Insulin-Like Growth Factor I; IGF-I; Mechano Growth Factor; MGF; Somatomedin-C; IGF1; IBP1
Species:  
Source:  
loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-P70698
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGF1; IGF-1; insulin-like growth factor 1; Insulin-like growth factor I; Somatomedin C; somatomedin-C
Species:  
Source:  
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-110135A
Purity:  99.42%
Target:  

IGF-1R

Research Areas:  

Neurological Disease

NBI-31772 hydrate is a potent inhibitor of interaction between insulin-like growth factor (IGF) and IGF-binding proteins (IGFBPs). NBI-31772 hydrate is also a nonpeptide ligand that releases bioactive IGF-I from the IGF-I/IGFBP-3 complex (Kis=1-24 nM for all six human subtypes). Anxiolytic and antidepressant-like effects .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-P7203
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rRtIGF-I; Somatomedin C; IGF1; Mechano growth factor
Species:  
Rat
Source:  
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-16381A
CAS No.: 396091-76-2
Synonyms: SOM230 acetate
Target:  

Somatostatin Receptor

Research Areas:  

Endocrinology Cancer

Pasireotide (SOM230) acetate, a long-acting cyclohexapeptide somatostatin analogue, can improve agonist activity at somatostatin receptors (subtypes sst1/2/3/4/5, pKi=8.2/9.0/9.1/<7.0/9.9, respectively). Pasireotide acetate can suppress GH, IGF-I and ACTH secretion, indicating potential efficacy in acromegaly and Cushing's disease. Pasireotide acetate also exhibits antisecretory, antiproliferative, and proapoptotic activity .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-13686
CAS No.: 196868-63-0
Purity:  99.85%
Target:  

IGF-1R Apoptosis

Research Areas:  

Cancer

PQ401 is a potent inhibitor of IGF-IR signaling. PQ401 inhibits IGF-I-stimulated IGF-IR autophosphorylation with an IC50 of 12.0 μM in a series of studies in MCF-7 cells. PQ401 is effective at inhibiting IGF-I-stimulated growth of MCF-7 cells (IC50, 6 μM). PQ401 is a potential agent for breast and other IGF-I-sensitive cancers. PQ401 induces caspase-mediated apoptosis .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P70783
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Long R3 IGF-I; Insulin-like growth factor I; MGF; Somatomedin-C; IBP1
Species:  
Source:  
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P78723
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IGF1R; IGFR; JTK13; CD221; MGC142170; MGC142172; MGC18216
Species:  
Source:  
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P700478
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Insulin-Like Growth Factor I; IGF-I; Mechano Growth Factor; MGF; Somatomedin-C; IGF1; IBP1
Species:  
Source:  
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P700093AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Somatamedin C; IGF-IA; Insulin-Like Growth Factor I; IGF-I; Mechano Growth Factor; MGF; Somatomedin-C; IGF1; IBP1
Species:  
Source:  
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P704374
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Somatamedin C; IGF-IA; Insulin-Like Growth Factor I; IGF-I; Mechano Growth Factor; MGF; Somatomedin-C; IGF1; IBP1
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-108905
CAS No.: 68562-41-4
Synonyms: Human IGF-I; FK 780
Target:  

IGF-1R

Research Areas:  

Metabolic Disease

Mecasermin (Human IGF-I; FK 780) is a recombinant human insulin-like growth factor I (IGF-I). Mecasermin has the potential for the study of the growth failure of growth hormone (GH) insensitivity caused by GH receptor defects or GH-inhibiting antibodies .
loading...
    loading...
Cat. No.: HY-P1777
CAS No.: 135861-49-3
Synonyms: Insulin-like Growth Factor I (24-41)
Target:  

IGF-1R

IGF-I (24-41) (Insulin-like Growth Factor I (24-41)) is amino acids 24 to 41 fragment of IGF-I. IGF-I, a 70 aa polypeptide hormone, is a trophic factor for both neurons and glial cells. IGF-I is partly responsible for systemic growth hormone (GH) activities. IGF-I has anabolic, antioxidant, anti-inflammatory and cytoprotective actions. IGF-I (24-41) regulates somatic growth and behavioral development .
loading...
    loading...
Cat. No.: HY-P3226
CAS No.: 147819-32-7
JB-1, an IGF-I analog, is a selective IGF-I receptor inhibitor that does not interact with IGF-II. JB-1 competes with IGF-I for binding to IGF-1R and blocks receptor autophosphorylation. JB-1 increases the level of sVEGFR-1. JB-1 normalizes retinal abnormalities, including reducing retinal neovascularization. JB-1 is applicable to studies related to oxygen-induced retinopathy .
loading...
    loading...
Cat. No.: HY-P3596A
Synonyms: Mouse growth hormone-releasing factor TFA
Target:  

GHSR

Research Areas:  

Endocrinology

GHRF, mouse TFA, a mouse growth hormone-releasing factor, is a peptide containing 44 amino acids. GHRF, mouse TFA stimulates the release and synthesis of growth hormone .
loading...
    loading...
Cat. No.: HY-P1777A
Synonyms: Insulin-like Growth Factor I (24-41) TFA
Target:  

IGF-1R

IGF-I (24-41) (Insulin-like Growth Factor I (24-41)) TFA is amino acids 24 to 41 fragment of IGF-I. IGF-I TFA, a 70 aa polypeptide hormone, is a trophic factor for both neurons and glial cells. IGF-I TFA is partly responsible for systemic growth hormone (GH) activities. IGF-I TFA has anabolic, antioxidant, anti-inflammatory and cytoprotective actions. IGF-I (24-41) TFA regulates somatic growth and behavioral development .
loading...
    loading...
Cat. No.: HY-P1773
CAS No.: 82177-09-1
Synonyms: Insulin-like Growth Factor I (30-41)
IGF-I (30-41) is amino acids 30 to 41 fragment of Insulin-like Growth Factor I (IGF-I). IGF-I is partly responsible for systemic GH activities although it possesses a wide number of own properties (anabolic, antioxidant, anti-inflammatory and cytoprotective actions) .
loading...
    loading...